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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Sep 30, 2024 | 4:52 PM IST

Rasuric Injection is used to treat high levels of uric acid (a natural substance that builds up in the blood as tumors break down) in people with certain types of cancer who are being treated with chemotherapy medications. It works by breaking down uric acid so that the body can eliminate it. Rasuric Injection may cause nausea, vomiting, constipation, diarrhoea, abdominal pain, mouth sores, throat pain, headache, anxiety, joint pain and fever.

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Prescription drug

Whats That

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Prescription drug
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Manufacturer/Marketer

Aureate Healthcare

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Rasuric Injection

Rasuric Injection is a recombinant version of the enzyme urate oxidase used to reduce uric acid levels in patients with leukaemia, lymphoma, and solid tumor malignancies receiving anti-cancer therapy. Leukaemia, or blood cancer, is a cancer of blood cells or blood-forming tissues. Lymphoma is a cancer of the lymphatic system.

Rasuric Injection contains Rasburicase, which belongs to the class of recombinant urate-oxidase enzymes. It works by metabolising the recombinant urate oxidase enzyme and thus helps clear the uric acid levels.

Rasuric Injection may cause certain side effects such as vomiting, nausea, fever, constipation, diarrhoea, oedema, headache, abdominal pain, anxiety, and injection site reactions. Most of these side effects of Rasuric Injection do not require medical attention and gradually resolve over time. A trained healthcare professional will administer Rasuric Injection. Hence, do not self-administer.

If you are allergic to Rasuric Injection, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with Rasuric Injection. Rasuric Injection is contraindicated for pregnant women and breastfeeding women due to serious fetal harm. Hence, inform your doctor if you are pregnant or planning to become pregnant. Inform your doctor if you have/had kidney or liver disease.

Uses of Rasuric Injection

Helps remove excess uric acid levels in patients with leukaemia, lymphoma, and solid tumor malignancies.

Medicinal Benefits

Rasuric Injection contains Rasburicase, which belongs to the recombinant urate-oxidase class of drugs. It works directly by metabolising the recombinant urate oxidase enzyme. This converts into allantoin, which is more soluble in urine. It makes it easier for the kidneys to excrete uric acid from the body.

Directions for Use

Your oncology doctor will administer Rasuric Injection. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rasuric Injection

  • Vomiting
  • Nausea
  • Loss of appetite
  • Diarrhoea
  • Dizziness
  • Anxiety
  • Stomach pain
  • Headache
  • Peripheral edema
  • Injection site reactions
  • Pain at the site of injection

Drug Warnings

Inform your doctor if you develop any allergic reactions after receiving Rasuric Injection. Inform your doctor about your complete medical and medication history before starting treatment with Rasuric Injection. Rasuric Injection is contraindicated for pregnant women and breastfeeding women due to serious fetal harm. Hence, inform your doctor if you are pregnant or planning to become pregnant. Rasuric Injection may cause severe hypersensitivity reactions, anaphylactic reactions, methemoglobinemia, and hemolysis in some patients. Hence, inform your doctor if you have/had any pre-existing liver or kidney disease. Avoid alcohol consumption with Rasuric Injection as it may cause serious side effects. Avoid breastfeeding while receiving Rasuric Injection as it can cause harm to the baby. This medicine is contraindicated in patients with G6PD deficiency.

Drug Interactions

Drug-Drug Interactions: No interactions found.

Drug-Food Interactions: Rasuric Injection may interact with alcohol. Therefore, avoid alcohol consumption with Rasuric Injection as it may increase the risk of liver damage.

Drug-Disease Interactions: Inform your doctor if you have liver or kidney disease before starting treatment with Rasuric Injection.

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Rasuric Injection as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Quit smoking.

Special Advise

  • Regular blood tests are recommended while taking Rasuric Injection to monitor the number and type of cells in the blood.
  • Blood uric acid levels should be monitored, and be ready to utilize any supportive or pharmacologic interventions that may be required to address this condition.
  • The uric acid blood samples should be collected in pre-chilled tubes containing heparin and immediately immerse and maintain the sample in an ice water bath.

Disease/Condition Glossary

Lymphoma: Lymphoma is a cancer of the lymphatic system, which is the body’s disease-fighting system. It includes lymph nodes, spleen, bone marrow, and thymus.

Leukaemia: Also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

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Alcohol

Consult your doctor

It is unknown whether Rasuric Injection interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Rasuric Injection. You should not become pregnant while on treatment with Rasuric Injection.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. If you are breastfeeding, inform your doctor before receiving Rasuric Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Caution

Rasuric Injection is administered as a single dose in a hospital setting. however Rasuric Injection may cause dizziness; therefore, avoid driving vehicles or operating machinery until you return to normal.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Rasuric Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Rasuric Injection as it may lead to kidney failure. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

Please consult your doctor. Rasuric Injection can be used in children if prescribed.

Country of origin

India

Manufacturer/Marketer address

S-40, 2Nd Floor, Janta Market, Rajouri Garden, New Delhi - 110 027. India
Other Info - RAS0097

FAQs

Rasuric Injection is used to help remove excess uric acid levels in patients with leukaemia, lymphoma, and solid tumour malignancies.
Rasuric Injection contains Rasburicase, which works by metabolizing the recombinant urate oxidase enzyme and thus helps clear the uric acid levels.
Rasuric Injection is known to cause severe hypersensitivity reactions, hemolysis, and methemoglobinemia in some patients. Hence, inform your doctor about your complete medical and medication history before starting the treatment.

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Keep Refrigerated. Do not freeze.Prepaid payment required.