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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 23, 2024 | 4:49 PM IST
P-Zide 1000 Tablet is used to treat and prevent tuberculosis. It contains Pyrazinamide which converts a special enzyme to an active form that inhibits the synthesis of fatty acids; this disrupts the cell membrane and disables energy production necessary for the survival of the TB bacteria. It may cause common side effects such as muscle/joint pain, nausea, vomiting and loss of appetite. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

PYRAZINAMIDE-1000MG

Manufacturer/Marketer :

Cadila Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About P-Zide 1000 Tablet

P-Zide 1000 Tablet is used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine and bone marrow. P-Zide 1000 Tablet does not work against infections caused by the virus, such as the common cold and flu.

P-Zide 1000 Tablet contains 'Pyrazinamide'. Pyrazinamide is a chemically synthesised bacteriocidal antibiotic. It converts a special enzyme to an active form that inhibits the synthesis of fatty acids; this disrupts the cell membrane and disables energy production necessary for the survival of the TB bacteria.

Your doctor will decide the dose and duration based on the severity of your disease. Common side effects of P-Zide 1000 Tablet include muscle/joint pain, nausea, vomiting and loss of appetite. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting P-Zide 1000 Tablet . Please tell your doctor if you are allergic to P-Zide 1000 Tablet or its components. Inform your doctor beforehand if you have a history of liver or kidney diseases, diabetes, gout, high uric acid level in the blood, alcohol use and are undergoing dialysis. It is essential to let your doctor know if you are pregnant, planning to conceive or are a breastfeeding mother. Avoid consuming alcohol along with P-Zide 1000 Tablet as it might lead to liver problems.

Uses of P-Zide 1000 Tablet

Treatment of Tuberculosis (TB).

Medicinal Benefits

P-Zide 1000 Tablet contains 'Pyrazinamide', which is used to treat and prevent tuberculosis. Pyrazinamide is a chemically synthesised bacteriocidal antibiotic. It converts a special enzyme to an active form that inhibits the synthesis of fatty acids; this disrupts the cell membrane and disables energy production necessary to survive the TB bacteria. It is usually given in alone or combined with other antitubercular agents to treat tuberculosis.

Side Effects of P-Zide 1000 Tablet

  • Muscle/joint pain

  • Nausea

  • Vomiting

  • Loss of appetite

  • Hepatitis, liver dysfunction

Directions for Use

Swallow P-Zide 1000 Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Brief your medical history to the doctor if you have any liver or kidney diseases, diabetes, gout, high uric acid level in the blood, lactose intolerance, alcohol use and are undergoing dialysis treatment before starting P-Zide 1000 Tablet . Let your doctor know if you are undergoing any vaccinations with live bacterial vaccines (like typhoid vaccine) since P-Zide 1000 Tablet may affect vaccine's activity. Please consult your doctor know if you are pregnant, planning to conceive or are a breastfeeding mother before starting P-Zide 1000 Tablet . Avoid consuming alcohol along with P-Zide 1000 Tablet as it might lead to liver problems. Store P-Zide 1000 Tablet below 25°C away from direct sunlight.

Therapeutic Class

ANTI- TUBERCULOSIS

Drug-Drug Interactions

verifiedApollotooltip
PyrazinamideKetoconazole
Severe
PyrazinamideLeflunomide
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.

  • Foods rich in vitamin C, such as kiwi, broccoli and bell pepper, help improve the immune system.

  • Avoid processed and fried foods.

  • Warm ginger tea or warm soup can help in providing relief from the cough.

  • Avoid foods and drinks, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer.

  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

What if I have taken an overdose of P-Zide 1000 Tablet

Do not take more than the prescribed dose of P-Zide 1000 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Other Info - PZI0003

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