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Written By , M Pharmacy
Reviewed By , M Pharmacy
Last Updated Jan 1, 2025 | 2:48 PM IST
Pzide 500 mg Tablet is used to treat and prevent tuberculosis. It contains Pyrazinamide which converts a special enzyme to an active form that inhibits the synthesis of fatty acids; this disrupts the cell membrane and disables energy production necessary for the survival of the TB bacteria. It may cause common side effects such as muscle/joint pain, nausea, vomiting and loss of appetite. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition :

PYRAZINAMIDE-500MG

Manufacturer/Marketer :

Cadila Healthcare Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Pzide 500 mg Tablet

Pzide 500 mg Tablet is used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine and bone marrow. Pzide 500 mg Tablet does not work against infections caused by the virus, such as the common cold and flu.

Pzide 500 mg Tablet contains 'Pyrazinamide'. Pyrazinamide is a chemically synthesised bacteriocidal antibiotic. It converts a special enzyme to an active form that inhibits the synthesis of fatty acids; this disrupts the cell membrane and disables energy production necessary for the survival of the TB bacteria.

Your doctor will decide the dose and duration based on the severity of your disease. Common side effects of Pzide 500 mg Tablet include muscle/joint pain, nausea, vomiting and loss of appetite. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting Pzide 500 mg Tablet . Please tell your doctor if you are allergic to Pzide 500 mg Tablet or its components. Inform your doctor beforehand if you have a history of liver or kidney diseases, diabetes, gout, high uric acid level in the blood, alcohol use and are undergoing dialysis. It is essential to let your doctor know if you are pregnant, planning to conceive or are a breastfeeding mother. Avoid consuming alcohol along with Pzide 500 mg Tablet as it might lead to liver problems.

Uses of Pzide 500 mg Tablet

Treatment of Tuberculosis (TB).

Medicinal Benefits

Pzide 500 mg Tablet contains 'Pyrazinamide', which is used to treat and prevent tuberculosis. Pyrazinamide is a chemically synthesised bacteriocidal antibiotic. It converts a special enzyme to an active form that inhibits the synthesis of fatty acids; this disrupts the cell membrane and disables energy production necessary to survive the TB bacteria. It is usually given in alone or combined with other antitubercular agents to treat tuberculosis.

Side Effects of Pzide 500 mg Tablet

  • Muscle/joint pain

  • Nausea

  • Vomiting

  • Loss of appetite

  • Hepatitis, liver dysfunction

Directions for Use

Swallow Pzide 500 mg Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Brief your medical history to the doctor if you have any liver or kidney diseases, diabetes, gout, high uric acid level in the blood, lactose intolerance, alcohol use and are undergoing dialysis treatment before starting Pzide 500 mg Tablet . Let your doctor know if you are undergoing any vaccinations with live bacterial vaccines (like typhoid vaccine) since Pzide 500 mg Tablet may affect vaccine's activity. Please consult your doctor know if you are pregnant, planning to conceive or are a breastfeeding mother before starting Pzide 500 mg Tablet . Avoid consuming alcohol along with Pzide 500 mg Tablet as it might lead to liver problems. Store Pzide 500 mg Tablet below 25°C away from direct sunlight.

Therapeutic Class

ANTI- TUBERCULOSIS

Drug-Drug Interactions

verifiedApollotooltip
PyrazinamideLomitapide
Severe
PyrazinamideKetoconazole
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.

  • Foods rich in vitamin C, such as kiwi, broccoli and bell pepper, help improve the immune system.

  • Avoid processed and fried foods.

  • Warm ginger tea or warm soup can help in providing relief from the cough.

  • Avoid foods and drinks, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer.

  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

How Pzide 500 mg Tablet Works

Pzide 500 mg Tablet contains 'Pyrazinamide'. Pyrazinamide is a chemically synthesised bacteriocidal antibiotic. It converts a special enzyme to an active form that inhibits the synthesis of fatty acids; this disrupts the cell membrane and disables energy production necessary for the survival of the TB bacteria.

What if I have taken an overdose of Pzide 500 mg Tablet

Do not take more than the prescribed dose of Pzide 500 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Pzide 500 mg Tablet . Alcohol intake, along with Pzide 500 mg Tablet , may cause increased liver damage. Please consult your doctor for more information.

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Pregnancy

Caution

Pzide 500 mg Tablet should be used with caution during pregnancy. Please consult your doctor before taking Pzide 500 mg Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Pzide 500 mg Tablet is not recommended for use during breastfeeding since it is excreted into the breast milk and may harm a nursing baby. Please consult your doctor if you are a breastfeeding mother.

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Driving

Caution

It is not known if Pzide 500 mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Caution

Pzide 500 mg Tablet is not recommended in patients with severe liver damage. Please consult your doctor since Pzide 500 mg Tablet should be used with caution in patients with liver impairment/liver disease. Regular monitoring of the liver with liver function tests is also advised.

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Kidney

Caution

Please consult your doctor since Pzide 500 mg Tablet should be used with caution in patients with kidney impairment/kidney disease. Your doctor may adjust the dosage in case of renal dysfunction.

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Children

Caution

Pzide 500 mg Tablet is recommended in children below 12 years of age only after doctor's advice.

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Other Info - PZI0002

Author Details

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FAQs

Pzide 500 mg Tablet is used to treat and prevent tuberculosis.
Pzide 500 mg Tablet contains 'Pyrazinamide.' It is bactericidal and works by stopping the growth of Mycobacterium tuberculosis, a bacteria that causes tuberculosis.
Pzide 500 mg Tablet is not recommended for use in the medical history of liver or kidney diseases, diabetes, gout, high uric acid level in the blood, alcohol use and undergoing dialysis treatment. Please let your doctor know if you have any other medical problems before starting Pzide 500 mg Tablet .
Pzide 500 mg Tablet can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor before you start Pzide 500 mg Tablet if you are undergoing any vaccinations.
It is advised to take Pzide 500 mg Tablet 30 minutes before food or 2 hours after food. Please consult your doctor for more information.
Pzide 500 mg Tablet gets converted in the body to Pyrazinoic acid that blocks the excretion of urates (salt form of uric acid) by the kidneys. Increased blood levels of uric acid (hyperuricemia) causes pain, swelling, redness and stiffness in joints (gout). Hence, Pzide 500 mg Tablet should be avoided if you have a history of gout.
Pzide 500 mg Tablet is an antibiotic that belongs to the group of anti-tuberculosis (TB) drugs. It is used for the treatment of tuberculosis which is an infectious disease that mainly affects lungs but can also impact other parts of the body.
Yes, Pzide 500 mg Tablet is bactericidal. It works by inhibiting the growth of Mycobacterium tuberculosis, the bacteria that is responsible for causing tuberculosis.
Pzide 500 mg Tablet causes hyperuricemia and gout by inhibiting the renal excretion of uric acid, which can lead to the precipitation or worsening of gout. It should be used with caution in individuals with hyperuricemia or a history of gout.
The side effects of Pzide 500 mg Tablet include nausea, vomiting, muscle/joint pain, nausea and loss of appetite. Consult the doctor if any of these symptoms persist or worsen.

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