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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Pulmosil Injection 12.5 ml belongs to the group of medicines called phosphodiesterase-5 (PDE-5) inhibitors. It is mainly used in the treatment of pulmonary arterial hypertension (high blood pressure in the lungs). This medicine contains sildenafil which helps increase the blood supply by relaxing the blood vessels. Common side effects include headache, indigestion, flushing, insomnia, and diarrhoea.
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Whats That

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Composition :

SILDENAFIL-0.8MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Pulmosil Injection 12.5 ml

Pulmosil Injection 12.5 ml belongs to the group of medicines called phosphodiesterase-5 (PDE-5) inhibitors used to treat pulmonary arterial hypertension (high blood pressure in the lungs), to improve the ability to exercise and to slow down clinical worsening.
 
Pulmosil Injection 12.5 ml contains 'Sildenafil' that relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.
 
In some cases, Pulmosil Injection 12.5 ml may cause side effects such as headache, indigestion, flushing, insomnia, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Do not take Pulmosil Injection 12.5 ml if you are allergic to any of the components or if you are taking nitrate medicines or riociguat (a drug used to treat pulmonary hypertension). Pulmosil Injection 12.5 ml is not recommended for use in children. Consult your doctor if you experience hearing or visual impairment.

Uses of Pulmosil Injection 12.5 ml

Treatment of Pulmonary arterial hypertension (PAH)

Directions for Use

Pulmosil Injection 12.5 ml will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Pulmosil Injection 12.5 ml belongs to the group of medicines called phosphodiesterase type-5 (PDE-5) inhibitors used to treat pulmonary arterial hypertension (high blood pressure in the lungs) to improve the ability to exercise and to slow down clinical worsening. Pulmosil Injection 12.5 ml relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension. 

How Pulmosil Injection 12.5 ml Works

Pulmosil Injection 12.5 ml contains 'Sildenafil' that relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pulmosil Injection 12.5 ml

  • Headache
  • Indigestion
  • Flushing
  • Insomnia (sleep disorder)
  • Diarrhoea

What if I have taken an overdose of Pulmosil Injection 12.5 ml

Pulmosil Injection 12.5 ml is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. Immediately notify your physician if you experience any of the following symptoms: unusual fatigue or weakness, sweating, confusion, dizziness, faintness, or lightheadedness when getting up quickly from a sitting or lying position. Your doctor may initiate necessary treatment if an overdose is suspected.

Drug Warnings

Do not take Pulmosil Injection 12.5 ml if you are allergic to any of the components, if you are taking medicines called nitrates which are used to treat angina or chest pain or guanylate cyclase stimulator medicines (medicines used to treat heart failure and PAH). Inform your doctor if you have/had heart problems such as angina, heart attack, irregular heartbeat, or heart failure, blood circulation problems, low blood pressure, eye or ear problems, sickle cell anaemia (an abnormality of red blood cells), multiple myeloma (cancer of bone marrow) or leukaemia (cancer of blood cells), stomach ulcer, bleeding problems, problems with the shape of the penis or Peyronie's disease (a condition that causes painful erections).

Drug-Drug Interactions

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SildenafilRitonavir
Critical
SildenafilSaquinavir
Critical

Drug-Drug Interactions

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SildenafilRitonavir
Critical
How does the drug interact with Pulmosil Injection 12.5 ml:
Coadministration of Ritonavir and Pulmosil Injection 12.5 ml may significantly increase the blood levels of Pulmosil Injection 12.5 ml.

How to manage the interaction:
Taking Pulmosil Injection 12.5 ml with Ritonavir together is generally avoided as it can possibly result in an interaction, it can be taken only if your doctor has advised it. If you notice any of these symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact a doctor. Do not discontinue any medications without consulting a doctor.
SildenafilSaquinavir
Critical
How does the drug interact with Pulmosil Injection 12.5 ml:
Coadministration of Saquinavir and Pulmosil Injection 12.5 ml can increase the blood levels and side effects of Pulmosil Injection 12.5 ml.

How to manage the interaction:
Taking Saquinavir and Pulmosil Injection 12.5 ml together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilIndinavir
Critical
How does the drug interact with Pulmosil Injection 12.5 ml:
Coadministration of Indinavir and Pulmosil Injection 12.5 ml can increase the blood levels and side effects of Pulmosil Injection 12.5 ml.

How to manage the interaction:
Taking Indinavir and Pulmosil Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilRiociguat
Critical
How does the drug interact with Pulmosil Injection 12.5 ml:
Co-administration of Pulmosil Injection 12.5 ml with Riociguat may lower the blood pressure.

How to manage the interaction:
Taking Riociguat and Pulmosil Injection 12.5 ml together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SildenafilFosamprenavir
Critical
How does the drug interact with Pulmosil Injection 12.5 ml:
Coadministration of Fosamprenavir and Pulmosil Injection 12.5 ml can increase the blood levels and effects of Pulmosil Injection 12.5 ml.

How to manage the interaction:
Taking Fosamprenavir and Pulmosil Injection 12.5 ml together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilAmyl nitrite
Critical
How does the drug interact with Pulmosil Injection 12.5 ml:
Combining Amyl nitrite and Pulmosil Injection 12.5 ml can increase the risk or severity of lower blood pressure.

How to manage the interaction:
Taking Amyl nitrite and Pulmosil Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken only when advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilDarunavir
Critical
How does the drug interact with Pulmosil Injection 12.5 ml:
Combining Darunavir and Pulmosil Injection 12.5 ml can increase the blood levels and effects of Pulmosil Injection 12.5 ml.

How to manage the interaction:
Taking Darunavir and Pulmosil Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilAtazanavir
Critical
How does the drug interact with Pulmosil Injection 12.5 ml:
Combining Atazanavir and Pulmosil Injection 12.5 ml can increase the blood levels and side effects of Pulmosil Injection 12.5 ml.

How to manage the interaction:
Taking Atazanavir and Pulmosil Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilTelaprevir
Critical
How does the drug interact with Pulmosil Injection 12.5 ml:
Combining Telaprevir and Pulmosil Injection 12.5 ml can increase the blood levels and effects of Pulmosil Injection 12.5 ml.

How to manage the interaction:
Taking Telaprevir and Pulmosil Injection 12.5 ml together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilNitroprusside
Critical
How does the drug interact with Pulmosil Injection 12.5 ml:
Coadministration of Pulmosil Injection 12.5 ml with Nitroprusside can increase the risk of developing low blood pressure.

How to manage the interaction:
Taking Pulmosil Injection 12.5 ml with Nitroprusside together is generally avoided as it can lead to an interaction, it can be taken only if prescribed by your doctor. If you experience any side effects such as dizziness, lightheadedness, headache, or heart palpitations you should seek immediate medical attention. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Lower your intake of salt. This helps in reducing the risk of developing oedema.
  • Include vegetables, fruits, whole grains, lean meats, poultry, fish, and fat-free/low-fat dairy products in your diet.
  • Avoid canned foods, processed foods, pickled, and frozen food. Instead, consume fresh foods.
  • Limit consumption of caffeine and alcohol as they can alter blood pressure.
  • Monitor fluid intake to prevent swelling/fluid retention.

Habit Forming

No

Therapeutic Class

PDE5-INHIBITORS

Pulmosil Injection 12.5 ml Substitute

Substitutes safety advice
  • Assurans 0.8Mg Injection 10Mg/12.5Ml

    by AYUR

    179.67per tablet
  • Cyldena 10 mg Injection 12.5 ml

    180.00per tablet
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Alcohol

Caution

It is not known if alcohol affects Pulmosil Injection 12.5 ml. Please consult your doctor.

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Pregnancy

Caution

Consult your doctor if you are pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if Pulmosil Injection 12.5 ml passes into breastmilk. Consult your doctor if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Pulmosil Injection 12.5 ml may cause dizziness; therefore, you are advised to drive and operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Pulmosil Injection 12.5 ml in patients with liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Pulmosil Injection 12.5 ml in patients with kidney disease.

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Children

Unsafe

Pulmosil Injection 12.5 ml is not recommended for children as safety and effectiveness have not been established.

FAQs

Pulmosil Injection 12.5 ml belongs to the group of medicines called phosphodiesterase-5 (PDE-5) inhibitors used to treat pulmonary arterial hypertension (high blood pressure in the lungs), to improve the ability to exercise and to slow down clinical worsening.
Pulmosil Injection 12.5 ml relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.
Diarrhoea might be a side effect of Pulmosil Injection 12.5 ml. Eat non-spicy food and drink fluids if you experience diarrhoea. Consult your doctor if the condition persists or worsens.
Do not to take Pulmosil Injection 12.5 ml with nitrates. Taking Pulmosil Injection 12.5 ml with medicines used to treat angina/chest pain such as nitrates/nitroglycerin may cause severe lowering of blood pressure. Consult your doctor if you have a history of heart attack/stroke.
Pulmosil Injection 12.5 ml has vasodilation properties which may cause low blood pressure (hypotension). Therefore, inform your doctor if you have resting hypotension, fluid depletion, autonomic dysfunction (dysfunction of the nerves), or severe left ventricular outflow obstruction.
When taken along with vitamin K antagonists, Pulmosil Injection 12.5 ml might increase the risk of bleeding. Consult your doctor if you are taking any vitamin K antagonists.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - PUL0093

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