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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Pulmosil Injection 12.5 ml belongs to the group of medicines called phosphodiesterase-5 (PDE-5) inhibitors. It is mainly used in the treatment of pulmonary arterial hypertension (high blood pressure in the lungs). This medicine contains sildenafil which helps increase the blood supply by relaxing the blood vessels. Common side effects include headache, indigestion, flushing, insomnia, and diarrhoea.
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Prescription drug

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Composition

SILDENAFIL-0.8MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Pulmosil Injection 12.5 ml

Pulmosil Injection 12.5 ml belongs to the group of medicines called phosphodiesterase-5 (PDE-5) inhibitors used to treat pulmonary arterial hypertension (high blood pressure in the lungs), to improve the ability to exercise and to slow down clinical worsening.
 
Pulmosil Injection 12.5 ml contains 'Sildenafil' that relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.
 
In some cases, Pulmosil Injection 12.5 ml may cause side effects such as headache, indigestion, flushing, insomnia, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Do not take Pulmosil Injection 12.5 ml if you are allergic to any of the components or if you are taking nitrate medicines or riociguat (a drug used to treat pulmonary hypertension). Pulmosil Injection 12.5 ml is not recommended for use in children. Consult your doctor if you experience hearing or visual impairment.

Uses of Pulmosil Injection 12.5 ml

Treatment of Pulmonary arterial hypertension (PAH)

Medicinal Benefits

Pulmosil Injection 12.5 ml belongs to the group of medicines called phosphodiesterase type-5 (PDE-5) inhibitors used to treat pulmonary arterial hypertension (high blood pressure in the lungs) to improve the ability to exercise and to slow down clinical worsening. Pulmosil Injection 12.5 ml relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension. 

Directions for Use

Pulmosil Injection 12.5 ml will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pulmosil Injection 12.5 ml

  • Headache
  • Indigestion
  • Flushing
  • Insomnia (sleep disorder)
  • Diarrhoea

Drug Warnings

Do not take Pulmosil Injection 12.5 ml if you are allergic to any of the components, if you are taking medicines called nitrates which are used to treat angina or chest pain or guanylate cyclase stimulator medicines (medicines used to treat heart failure and PAH). Inform your doctor if you have/had heart problems such as angina, heart attack, irregular heartbeat, or heart failure, blood circulation problems, low blood pressure, eye or ear problems, sickle cell anaemia (an abnormality of red blood cells), multiple myeloma (cancer of bone marrow) or leukaemia (cancer of blood cells), stomach ulcer, bleeding problems, problems with the shape of the penis or Peyronie's disease (a condition that causes painful erections).

Drug Interactions

Drug-Drug Interactions: Pulmosil Injection 12.5 ml may interact with nitrate medicines, guanylate cyclase stimulators (riociguat), protease inhibitors (ritonavir), alpha-blockers, anti-hypertensive medicines (amlodipine), and other PDE-5 inhibitors.

Drug-Food Interactions: Concomitant use of grapefruit and its juice with Pulmosil Injection 12.5 ml is not recommended.

Drug-Disease Interactions: Inform your doctor if you have/had heart problems, blood circulation problems, stomach ulcers, bleeding problems, penis deformity or Peyronie's disease (a condition that causes painful erections).

Drug-Drug Interactions Checker List

  • RIOCIGUAT
  • RITONAVIR
  • AMLODIPINE

Habit Forming

No

Diet & Lifestyle Advise

  • Lower your intake of salt. This helps in reducing the risk of developing oedema.
  • Include vegetables, fruits, whole grains, lean meats, poultry, fish, and fat-free/low-fat dairy products in your diet.
  • Avoid canned foods, processed foods, pickled, and frozen food. Instead, consume fresh foods.
  • Limit consumption of caffeine and alcohol as they can alter blood pressure.
  • Monitor fluid intake to prevent swelling/fluid retention.

Disease/Condition Glossary

Pulmonary arterial hypertension (PAH): High blood pressure affects the arteries in the lungs and heart leading to pulmonary arterial hypertension. It occurs due to narrowed or blocked blood vessels which increases the workload on the heart. Symptoms include chest pain, dizziness, fatigue, and swelling in the legs and ankles.

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Alcohol

Caution

It is not known if alcohol affects Pulmosil Injection 12.5 ml. Please consult your doctor.

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Pregnancy

Caution

Consult your doctor if you are pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if Pulmosil Injection 12.5 ml passes into breastmilk. Consult your doctor if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Pulmosil Injection 12.5 ml may cause dizziness; therefore, you are advised to drive and operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Pulmosil Injection 12.5 ml in patients with liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Pulmosil Injection 12.5 ml in patients with kidney disease.

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Children

Unsafe

Pulmosil Injection 12.5 ml is not recommended for children as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - PUL0093

Author Details

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FAQs

Pulmosil Injection 12.5 ml belongs to the group of medicines called phosphodiesterase-5 (PDE-5) inhibitors used to treat pulmonary arterial hypertension (high blood pressure in the lungs), to improve the ability to exercise and to slow down clinical worsening.
Pulmosil Injection 12.5 ml relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.
Diarrhoea might be a side effect of Pulmosil Injection 12.5 ml. Eat non-spicy food and drink fluids if you experience diarrhoea. Consult your doctor if the condition persists or worsens.
Do not to take Pulmosil Injection 12.5 ml with nitrates. Taking Pulmosil Injection 12.5 ml with medicines used to treat angina/chest pain such as nitrates/nitroglycerin may cause severe lowering of blood pressure. Consult your doctor if you have a history of heart attack/stroke.
Pulmosil Injection 12.5 ml has vasodilation properties which may cause low blood pressure (hypotension). Therefore, inform your doctor if you have resting hypotension, fluid depletion, autonomic dysfunction (dysfunction of the nerves), or severe left ventricular outflow obstruction.
When taken along with vitamin K antagonists, Pulmosil Injection 12.5 ml might increase the risk of bleeding. Consult your doctor if you are taking any vitamin K antagonists.

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