Cyldena 10 mg Injection 12.5 ml belongs to the group of medicines called phosphodiesterase-5 (PDE-5) inhibitors used to treat pulmonary arterial hypertension (high blood pressure in the lungs), to improve the ability to exercise and to slow down clinical worsening.
 
Cyldena 10 mg Injection 12.5 ml contains 'Sildenafil' that relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.
 
In some cases, Cyldena 10 mg Injection 12.5 ml may cause side effects such as headache, indigestion, flushing, insomnia, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Do not take Cyldena 10 mg Injection 12.5 ml if you are allergic to any of the components or if you are taking nitrate medicines or riociguat (a drug used to treat pulmonary hypertension). Cyldena 10 mg Injection 12.5 ml is not recommended for use in children. Consult your doctor if you experience hearing or visual impairment.

Cyldena 10 mg Injection 12.5 ml belongs to the group of medicines called phosphodiesterase type-5 (PDE-5) inhibitors used to treat pulmonary arterial hypertension (high blood pressure in the lungs) to improve the ability to exercise and to slow down clinical worsening. Cyldena 10 mg Injection 12.5 ml relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension. 

• Headache
• Indigestion
• Flushing
• Insomnia (sleep disorder)
• Diarrhoea

Do not take Cyldena 10 mg Injection 12.5 ml if you are allergic to any of the components, if you are taking medicines called nitrates which are used to treat angina or chest pain or guanylate cyclase stimulator medicines (medicines used to treat heart failure and PAH). Inform your doctor if you have/had heart problems such as angina, heart attack, irregular heartbeat, or heart failure, blood circulation problems, low blood pressure, eye or ear problems, sickle cell anaemia (an abnormality of red blood cells), multiple myeloma (cancer of bone marrow) or leukaemia (cancer of blood cells), stomach ulcer, bleeding problems, problems with the shape of the penis or Peyronie's disease (a condition that causes painful erections).

Drug-Drug Interactions: Cyldena 10 mg Injection 12.5 ml may interact with nitrate medicines, guanylate cyclase stimulators (riociguat), protease inhibitors (ritonavir), alpha-blockers, anti-hypertensive medicines (amlodipine), and other PDE-5 inhibitors.

Drug-Food Interactions: Concomitant use of grapefruit and its juice with Cyldena 10 mg Injection 12.5 ml is not recommended.

Drug-Disease Interactions: Inform your doctor if you have/had heart problems, blood circulation problems, stomach ulcers, bleeding problems, penis deformity or Peyronie's disease (a condition that causes painful erections).

• RIOCIGUAT
• RITONAVIR
• AMLODIPINE

• Lower your intake of salt. This helps in reducing the risk of developing oedema.
• Include vegetables, fruits, whole grains, lean meats, poultry, fish, and fat-free/low-fat dairy products in your diet.
• Avoid canned foods, processed foods, pickled, and frozen food. Instead, consume fresh foods.
• Limit consumption of caffeine and alcohol as they can alter blood pressure.
• Monitor fluid intake to prevent swelling/fluid retention.

Pulmonary arterial hypertension (PAH): High blood pressure affects the arteries in the lungs and heart leading to pulmonary arterial hypertension. It occurs due to narrowed or blocked blood vessels which increases the workload on the heart. Symptoms include chest pain, dizziness, fatigue, and swelling in the legs and ankles.