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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Proxym-MR Tablet is used to treat osteoarthritis, rheumatoid arthritis, pain, and muscle spasms. It contains Etodolac and Thiocolchicoside, which helps reduce mild to moderate pain and inflammation at the injured or damaged site. Alos, it helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms. It may cause common side effects such as nausea, vomiting, heartburn, stomach pain, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Proxym-MR Tablet

Proxym-MR Tablet is used to treat osteoarthritis, rheumatoid arthritis, pain, and muscle spasms. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage.
 
Proxym-MR Tablet is a combination of two drugs: Etodolac (NSAID) and Thiocolchicoside (Muscle relaxant). Etodolac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms.
 
You are advised to take Proxym-MR Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Proxym-MR Tablet may cause common side effects such as nausea, vomiting, heartburn, stomach pain, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Proxym-MR Tablet may cause drowsiness and dizziness, so drive with caution. Proxym-MR Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Proxym-MR Tablet as it could lead to increased dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Proxym-MR Tablet

Treatment of Osteoarthritis, rheumatoid arthritis, pain and muscle spasms.

Directions for Use

Take Proxym-MR Tablet with food to avoid stomach upset. Swallow Proxym-MR Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Proxym-MR Tablet is a combination of two drugs: Etodolac (Non-Steroidal Anti-Inflammatory Drugs) and Thiocolchicoside (Muscle relaxant). Proxym-MR Tablet is used to treat osteoarthritis, rheumatoid arthritis, pain, and muscle spasms. Etodolac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, prostaglandins, which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms.

How Proxym-MR Tablet Works

Proxym-MR Tablet is a combination of two drugs: Etodolac (NSAID) and Thiocolchicoside (Muscle relaxant). Etodolac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Proxym-MR Tablet

  • Nausea
  • Vomiting
  • Heartburn
  • Stomach pain
  • Indigestion

What if I have taken an overdose of Proxym-MR Tablet

Do not take more than the prescribed dose of Proxym-MR Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Proxym-MR Tablet if you are allergic to any of its contents; if you have stomach ulcers, bleeding problems, clotting problems, inflammatory bowel disease, severe heart, liver or kidney problems, galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Inform your doctor if you have/had stomach bleeding or ulcers, heart failure, high blood pressure, diabetes, high cholesterol, kidney or liver impairment. Consult your doctor if you are pregnant or breastfeeding. Proxym-MR Tablet may cause drowsiness and dizziness, so drive only if you are alert. Proxym-MR Tablet is not recommended for children as safety has not been established. Stop taking Proxym-MR Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Proxym-MR Tablet unless prescribed.

Drug-Drug Interactions

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EtodolacMeloxicam
Critical
EtodolacKetorolac
Critical

Drug-Drug Interactions

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EtodolacMeloxicam
Critical
How does the drug interact with Proxym-MR Tablet 10's:
Co-administration of Proxym-MR Tablet 10's with Meloxicam can raise the adverse consequences in the digestive system, including inflammation, bleeding, ulceration, and, in rare cases, perforation(rupture).

How to manage the interaction:
Taking Meloxicam with Proxym-MR Tablet 10's is not recommended can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness consult a doctor. Do not discontinue any medications without consulting a doctor.
EtodolacKetorolac
Critical
How does the drug interact with Proxym-MR Tablet 10's:
Using ketorolac together with Proxym-MR Tablet 10's may increase the risk of side effects in the gastrointestinal tract (inflammation, bleeding and ulceration).

How to manage the interaction:
Taking Proxym-MR Tablet 10's with Ketorolac is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacValdecoxib
Severe
How does the drug interact with Proxym-MR Tablet 10's:
When valdecoxib is used with Proxym-MR Tablet 10's, there is an increased risk of significant gastrointestinal toxicity (inflammation, bleeding, ulceration, and perforation).

How to manage the interaction:
Although taking Proxym-MR Tablet 10's and Valdecoxib together can cause an interaction, it can be taken if a doctor has suggested it. If you're having any of these symptoms like stomach problems, inflammation, bleeding, or ulcers, it's important to let a doctor know right away. Do not discontinue any medications without consulting a doctor.
EtodolacTinzaparin
Severe
How does the drug interact with Proxym-MR Tablet 10's:
Use of tinzaparin with Proxym-MR Tablet 10's may raise the risk of bleeding problems.

How to manage the interaction:
There may be a possibility of interaction between Proxym-MR Tablet 10's and Tinzaparin, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, consult doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacEverolimus
Severe
How does the drug interact with Proxym-MR Tablet 10's:
Everolimus can cause kidney problems, and taking it with Proxym-MR Tablet 10's, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Proxym-MR Tablet 10's and Everolimus, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
EtodolacDabigatran etexilate
Severe
How does the drug interact with Proxym-MR Tablet 10's:
When Proxym-MR Tablet 10's is taken with Dabigatran etexilate may increase the risk or severity of bleeding and hemorrhage.

How to manage the interaction:
Taking Dabigatran etexilate with Proxym-MR Tablet 10's together can result in an interaction, but it can be taken if a doctor has advised it. However, if you happen to have any unusual bleeding or bruising, or other signs and symptoms of bleeding, such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
EtodolacSulindac
Severe
How does the drug interact with Proxym-MR Tablet 10's:
Taking Sulindac with Proxym-MR Tablet 10's may raise the risk of gastrointestinal adverse effects (inflammation, bleeding, ulceration, and, in rare cases, perforation).

How to manage the interaction:
Taking Proxym-MR Tablet 10's with Sulindac together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacIomeprol
Severe
How does the drug interact with Proxym-MR Tablet 10's:
Taking Proxym-MR Tablet 10's and Iomeprol can increase the risk of kidney damage.

How to manage the interaction:
Taking Proxym-MR Tablet 10's with Iomeprol together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor immediately. Drink lots of fluid after the procedure to stay hydrated and to flush the contrast agent out of your kidneys. Do not stop using any medications without talking to a doctor.
EtodolacAdefovir dipivoxil
Severe
How does the drug interact with Proxym-MR Tablet 10's:
Taking Adefovir dipivoxil with Proxym-MR Tablet 10's can increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Proxym-MR Tablet 10's with Adefovir dipivoxil can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
EtodolacHuman immunoglobulin
Severe
How does the drug interact with Proxym-MR Tablet 10's:
Taking Human immunoglobulin with Proxym-MR Tablet 10's, may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Proxym-MR Tablet 10's together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Proxym-MR Tablet Substitute

Substitutes safety advice
  • Setolac-MR Tablet 10's

    by AYUR

    28.80per tablet
  • Etodor-MR Tablet 10's

    29.70per tablet
  • Thaiclo E Tablet 10's

    37.95per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Proxym-MR Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding; your doctor will decide whether Proxym-MR Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Proxym-MR Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Proxym-MR Tablet is not recommended for children as the safety and effectiveness were not established.

FAQs

Proxym-MR Tablet is used to treat osteoarthritis, rheumatoid arthritis, pain, and muscle spasms.
Proxym-MR Tablet is a combination of two drugs: Etodolac and Thiocolchicoside. Etodolac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, 'prostaglandins'. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms.
Proxym-MR Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis and rheumatoid arthritis. Arthritis is tenderness and swelling in the joints.
Avoid taking Proxym-MR Tablet if you have stomach ulcers, bleeding problems, or heart problems. Talk to your doctor regarding your concerns; he/she may prescribe alternate medicine.
Diarrhoea might be a side-effect of Proxym-MR Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Proxym-MR Tablet contains etodolac, which might make the skin sensitive to sunlight and may result in sunburn. Avoid exposure to sunlight and artificial UV rays such as tanning beds and sunlamps while taking Proxym-MR Tablet . Whenever you step out of the home, try to apply sunscreen.
Proxym-MR Tablet may increase the risk of fatal heart attack or stroke. If you have any recent heart bypass surgery, do not use Proxym-MR Tablet . Talk to your doctor before taking Proxym-MR Tablet if you have heart problems.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - PRO0963

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