Prostium E 0.06% Gel belongs to a group of medicines called oestrogen hormones used to prevent and treat hot flashes in women experiencing menopause. It is also used to treat vaginal itching, dryness, and burning sensations in women experiencing menopause.

Prostium E 0.06% Gel contains ''estradiol'', which works by replacing the oestrogen, which is normally produced by the ovaries, thereby providing relief from menopausal symptoms.

In some cases, Prostium E 0.06% Gel may cause side effects such as headache, breast pain or tenderness, diarrhoea, gas and heartburn. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant, think you are pregnant, are planning for pregnancy or are breastfeeding. Avoid smoking or going near open flame until Prostium E 0.06% Gel has dried as it may catch fire. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Prostium E 0.06% Gel belongs to a group of medicines called oestrogen hormones used to prevent and treat hot flashes in women experiencing menopause. It is also used to treat vaginal itching, dryness, and burning in women experiencing menopause. Prostium E 0.06% Gel contains ''estradiol'', which works by replacing the oestrogen, which is usually produced by the ovaries, thereby provides relief from menopausal symptoms.

• Headache
• Breast tenderness or pain
• Diarrhoea
• Gas
• Heartburn

Do not use Prostium E 0.06% Gel if you are allergic to any of its components. Inform your doctor if you have/had a hysterectomy (surgery to remove the uterus), abnormal or unusual vaginal bleeding, heart attack, stroke, breast cancer, blood clots, high blood pressure, high cholesterol or fat, diabetes, heart disease, breast lumps, lupus (the body attacks its own tissues causing damage and swelling), asthma, migraine headache, seizures, uterine fibroids (growths in the uterus that are non-cancerous), endometriosis (growth of the womb lining outside the womb), yellowing of the skin and eyes, very high/low levels of calcium, gallbladder, pancreas, thyroid, liver or kidney problems, porphyria (a condition in which abnormal substances build up in the blood and cause problems with the skin or nervous system) or if you smoke.

Drug-Drug Interactions: Inform your doctor if you are taking anti-fungal (itraconazole, ketoconazole), anti-convulsant (carbamazepine, phenobarbital), antibiotic (clarithromycin, erythromycin, rifampin), statins (lovastatin), anti-retroviral (ritonavir), medicines for thyroid disease, and herbal supplement (St. John's wort).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have/had a heart attack, stroke, abnormal/unusual vaginal bleeding, breast cancer, or blood clots.

• ITRACONAZOLE
• KETOCONAZOLE
• CARBAMAZEPINE
• PHENOBARBITAL
• CLARITHROMYCIN
• ERYTHROMYCIN
• RIFAMPIN
• LOVASTATIN
• RITONAVIR
• ST JOHN'S WORT

• Include foods such as soybeans, flax seeds, and soy products in your diet.
• Maintain a healthy weight by exercising regularly. Also, avoid exercising too much. Do it moderately.
• Drink plenty of water to stay hydrated.
• Try to limit alcohol and caffeine.
• Choose personnel care items that are pH balanced.

• Do not let anyone touch the skin where you have applied Prostium E 0.06% Gel for one hour. In case of accidental contact, ask them to wash immediately with soap.
• Make sure that the skin where you will apply Prostium E 0.06% Gel is clean and completely dry.
• Regular breast examinations and mammogram tests are recommended.
• Avoid contact of Prostium E 0.06% Gel with eyes; wash with plenty of water if contact occurs. Consult your doctor if you experience eye irritation.
• Consult your doctor immediately if you experience any of these symptoms: sudden, severe vomiting; sudden, severe headache; dizziness or faintness; speech problems; sudden complete or partial loss of vision; weakness or numbness of an arm or a leg; double vision; crushing chest pain or chest heaviness; breast lumps or other breast changes; discharge from nipples; coughing up blood; difficulty thinking clearly, remembering, or learning new things; sudden shortness of breath; or pain, tenderness, or redness in one leg.

Menopausal symptoms: Menopause is a condition in which a woman hasn’t had periods for 12 consecutive months. It usually begins between the ages of 45-55 years. Symptoms include hot flashes, vaginal itching, irritation, dryness, and a burning sensation. They occur due to a drop in the levels of oestrogen that naturally happens after menopause.