Prolavir LR Tablet belongs to a class of drugs called antiretrovirals used in the treatment of HIV infection. Prolavir LR Tablet helps in decreasing the chance of developing AIDS (acquired immunodeficiency syndrome). Prolavir LR Tablet may be used in combination with other antiviral drugs. HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

Prolavir LR Tablet is a combination of two antiretroviral drugs, namely: Lopinavir and Ritonavir. Lopinavir works by inhibiting the working of a protease enzyme that is essential for the reproduction of HIV. Thereby, it prevents the production of the new virus. Ritonavir slows the breakdown of Lopinavir by the liver and increases the levels of Lopinavir in the blood and making it effective against the virus. Together, they help to control HIV infection.

Take Prolavir LR Tablet as prescribed by your doctor. You are advised to take Prolavir LR Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience nausea, vomiting, diarrhea, upper respiratory tract infection, indigestion, decreased appetite, headache, or dizziness. Most of these side effects of Prolavir LR Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Prolavir LR Tablet or any other medicines, please tell your doctor. Prolavir LR Tablet is not recommended for children below 2 years of age as the safety and effectiveness were not established. If you are pregnant, planning for pregnancy, or breastfeeding, please consult a doctor before taking Prolavir LR Tablet. You are recommended to avoid the consumption of alcohol with Prolavir LR Tablet as it may increase the risk of liver damage. Drive only if you are alert as Prolavir LR Tablet may cause dizziness.

Prolavir LR Tablet contains Lopinavir and Ritonavir used in the treatment of HIV infection. Prolavir LR Tablet may be used in combination with other antiviral drugs. Lopinavir inhibits the working of the protease enzyme that is essential for the reproduction of HIV. Thereby, it prevents the production of the new virus. Ritonavir slows the breakdown of Lopinavir by the liver and increases the levels of Lopinavir in the blood and making it effective against the virus. Together, they help to control HIV infection by slowing the spread of infection in the body. Taking Prolavir LR Tablet along with practicing safe sex and lifestyle changes may reduce the risk of getting or transmitting HIV to others.

• Nausea
• Vomiting
• Diarrhoea
• Upper respiratory tract infection
• Indigestion
• Decreased appetite
• Headache
• Dizziness

If you are allergic to Prolavir LR Tablet or any other medicines, please tell your doctor. Prolavir LR Tablet is not recommended for children below 2 years of age as the safety and effectiveness were not established. If you are pregnant or planning for pregnancy, please consult a doctor before taking Prolavir LR Tablet. HIV-infected women are recommended to avoid breastfeeding as the baby may be infected through breast milk. Please consult a doctor if you are breastfeeding before taking Prolavir LR Tablet. You are recommended to avoid consumption of alcohol with Prolavir LR Tablet as it may increase the risk of liver damage. Drive only if you are alert as Prolavir LR Tablet may cause dizziness. You are advised to take proper precautions if you are infected with HIV infection to prevent the spread of infection to others through sexual contact or body fluids. If you experience stomach pain, difficulty in breathing, vomiting, nausea and severe weakness in the muscles of arms and legs, please consult a doctor immediately as these might be symptoms of increased lactic acid levels.

Drug-Drug Interaction: Prolavir LR Tablet may interact with anti-allergic drugs (astemizole, terfenadine), antianxiety drugs (triazolam, midazolam), antipsychotics (quetiapine, pimozide), antidepressants (lurasidone), cholesterol-lowering medicines (simvastatin, lovastatin), antibiotics (fusidic acid), medicines used to treat erectile dysfunction (sildenafil, vardenafil, avanafil), antacid (cisapride), drugs used to treat abnormal heartbeat (dronedarone, amiodarone), medicines used to treat headaches (dihydroergotamine, methylergonovine, ergotamine, ergonovine).

Drug-Food Interaction: Prolavir LR Tablet may interact with St. John’s wort (herbal medicine used to treat depression). Therefore, avoid taking Prolavir LR Tablet with St. John’s wort.

Drug-Disease Interaction: Do not take Prolavir LR Tablet if you have severe liver problems. If you have diabetes, high cholesterol, bleeding disorder, hemophilia type A or B, low levels of potassium in blood, pancreas, liver or heart problems,  inform your doctor before taking Prolavir LR Tablet.

• ASTEMIZOLE
• TERFENADINE
• TRIAZOLAM
• MIDAZOLAM
• QUETIAPINE
• PIMOZIDE
• LURASIDONE
• SIMVASTATIN
• LOVASTATIN
• FUSIDIC ACID
• SILDENAFIL
• VARDENAFIL
• AVANAFIL
• CISAPRIDE
• DRONEDARONE
• AMIODARONE
• DIHYDROERGOTAMINE
• METHYLERGONOVINE
• ERGOTAMINE
• ERGONOVINE

• Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
• Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
• Avoid sharing used needles, other injections, or drug equipment.
• Get tested for other sexually transmitted infections such as gonorrhea or syphilis as they can make you prone to HIV infection.
• Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
• Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
• Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
• Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.

Certain tests are recommended while taking Prolavir LR Tablet to monitor the changes in levels of blood lipids and glucose.

HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. HIV spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs.