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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Preva 75 Tablet is used for the prevention of heart attack or stroke in people at high risk of heart disease. It contains Clopidogrel, which helps in preventing the formation of harmful blood clots (plaque) in your veins. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, it helps prevent blood clots if you have an increased risk of having severe chest pain (unstable angina or heart attack), stroke, or peripheral arterial disease (heart problem due to narrowed blood vessels). In some cases, you may experience side effects such as nosebleeds, heavier periods, bleeding gums, easy bruising, diarrhoea, stomach pain, indigestion, or heartburn. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

CLOPIDOGREL-75MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Preva 75 Tablet

Preva 75 Tablet is used for the prevention of heart attack or stroke in people at high risk of heart disease. A heart attack generally refers to the blocked flow of blood to the heart because of the blockage of arteries. A heart blockage is most often a build-up of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Preva 75 Tablet belongs to a class of medications called a blood thinner or an antiplatelet medication. Preva 75 Tablet plays a vital role in preventing the formation of harmful blood clots (plaque) in your veins. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Preva 75 Tablet helps prevent blood clots if you have an increased risk of having severe chest pain (unstable angina or heart attack), stroke, or peripheral arterial disease (heart problem due to narrowed blood vessels).

The recommended daily dose of Preva 75 Tablet is 75 mg once daily orally, with or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience nosebleeds, heavier periods, bleeding gums, easy bruising, diarrhoea, stomach pain, indigestion, or heartburn. If the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Stopping a sudden intake of Preva 75 Tablet may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke. Let your doctor know if you have any liver, kidney, or heart problems. Preva 75 Tablet should be taken cautiously in pregnant or breastfeeding women. It should be not given to people with a bleeding disorder (haemophilia), active pathological bleeding, like a peptic ulcer, or bleeding in the brain (intracranial haemorrhage). Do not take Preva 75 Tablet with aspirin or ibuprofen for pain relief while you are using Preva 75 Tablet . It may increase the chance of having stomach ulcers or severe gastric bleeding.

Uses of Preva 75 Tablet

Prevention of heart attack, Prevention of stroke, Prevention of heart-related chest pain (angina).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Preva 75 Tablet plays a vital role in preventing the formation of harmful blood clots in your blood vessels by making platelets (clotting agents) stick together. Thus, it helps to reduce the risk of heart attack, stroke, unstable angina (heart-related chest pain), and peripheral arterial disease (blocked or poor blood flow due to narrowed blood vessels) in heart disease patients and patients who have undergone recent heart surgery with a stent.

How Preva 75 Tablet Works

Preva 75 Tablet belongs to a class of medications called a blood thinner or an antiplatelet medication. Preva 75 Tablet plays a vital role in preventing the formation of harmful blood clots (plaque) in your veins. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Preva 75 Tablet helps prevent blood clots if you have an increased risk of having severe chest pain (unstable angina or heart attack), stroke, or peripheral arterial disease (heart problem due to narrowed blood vessels).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Preva 75 Tablet

  • Nosebleeds
  • Heavier periods
  • Bleeding gums
  • Easy bruising
  • Diarrhoea
  • Stomach pain
  • Indigestion  or heartburn

What if I have taken an overdose of Preva 75 Tablet

Do not take more than the prescribed dose of Preva 75 Tablet as it may cause overdose. The symptoms of overdose include unusual bleeding or bruising. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Indigestion medicines known as proton pump inhibitors like omeprazole should be used with caution while taking Preva 75 Tablet . Prolonged use of Preva 75 Tablet can cause bleeding problems (like nosebleeds, heavier periods, bleeding gums, and easy bruising). If you are going to have any surgery, discontinue taking Preva 75 Tablet 5 days before the surgery. Discontinuation of Preva 75 Tablet might increase the risk of heart attack, stroke, and other risks of cardiovascular events. So, do not stop taking Preva 75 Tablet suddenly. If you have had a recent stroke or heart attack, stop the intake of Preva 75 Tablet with painkillers like aspirin or ibuprofen, as it can increase your stomach or gastrointestinal bleeding. Purpura (blood leakage under the skin) has been observed with the use of Preva 75 Tablet , including in fatal cases.

Drug-Drug Interactions

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ClopidogrelMifepristone
Critical
ClopidogrelSelexipag
Critical

Drug-Drug Interactions

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ClopidogrelMifepristone
Critical
How does the drug interact with Preva 75 Tablet 15's:
Taking Preva 75 Tablet 15's together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Preva 75 Tablet 15's with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
ClopidogrelSelexipag
Critical
How does the drug interact with Preva 75 Tablet 15's:
When Selexipag and Preva 75 Tablet 15's are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Preva 75 Tablet 15's with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
ClopidogrelArgatroban
Severe
How does the drug interact with Preva 75 Tablet 15's:
Taking Preva 75 Tablet 15's together with argatroban can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Preva 75 Tablet 15's and Apixaban, they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding, like feeling dizzy or lightheaded, red or black, sticky stools, or severe headaches. Do not discontinue any medications without consulting your doctor.
ClopidogrelFluconazole
Severe
How does the drug interact with Preva 75 Tablet 15's:
Co-administration of Preva 75 Tablet 15's with fluconazole can reduce the effectiveness of Preva 75 Tablet 15's.

How to manage the interaction:
Preva 75 Tablet 15's and Fluconazole may interact, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to your doctor.
ClopidogrelPanobinostat
Severe
How does the drug interact with Preva 75 Tablet 15's:
Taking Preva 75 Tablet 15's together with Panobinostat can increases the risk of bleeding.

How to manage the interaction:
Although taking Preva 75 Tablet 15's together with panobinostat can result in interaction, it can be taken if prescribed by a doctor. However, consult your doctor immediately if you experience dizziness, lightheadedness, redness or blackness, sticky stools, or severe headache. Do not discontinue any medication without consulting your doctor.
ClopidogrelProtamine
Severe
How does the drug interact with Preva 75 Tablet 15's:
Taking Protamine with Preva 75 Tablet 15's can increase the risk of bleeding.

How to manage the interaction:
Taking Protamine with Preva 75 Tablet 15's together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
ClopidogrelDabigatran etexilate
Severe
How does the drug interact with Preva 75 Tablet 15's:
Taking Preva 75 Tablet 15's with Dabigatran may increase the risk of bleeding.

How to manage the interaction:
Although there may be an interaction between Preva 75 Tablet 15's and Apixaban, they can be taken together if advised by your doctor. However, consult your doctor immediately if you experience any unusual bleeding, dizziness or lightheadedness, red or black, sticky stools, or headaches. Do not discontinue any medication without consulting your doctor.
ClopidogrelPrasugrel
Severe
How does the drug interact with Preva 75 Tablet 15's:
Taking Preva 75 Tablet 15's together with Prasugrel will have an additive effect and increase the risk of bleeding.

How to manage the interaction:
Although taking Preva 75 Tablet 15's together with Prasugrel may result in interaction, it can be taken if prescribed by a doctor. However, If you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, or having a severe headache, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
ClopidogrelCabozantinib
Severe
How does the drug interact with Preva 75 Tablet 15's:
Taking cabozantinib together with Preva 75 Tablet 15's may increase the risk of bleeding.

How to manage the interaction:
Taking Preva 75 Tablet 15's with Cabozantinib together can result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor immediately if you notice symptoms like bleeding, bruising, dizziness, or black stools. Do not stop using any medications without a doctor's advice.
ClopidogrelRabeprazole
Severe
How does the drug interact with Preva 75 Tablet 15's:
Taking Preva 75 Tablet 15's with Rabeprazole can reduce the effectiveness of Preva 75 Tablet 15's.

How to manage the interaction:
Taking Preva 75 Tablet 15's and Rabeprazole together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A low cholesterol diet and a regular exercise regime complement treatment with Preva 75 Tablet effectively.
  • Stick to a freshly prepared home-cooked meal and avoid processed, packed foods that contain hidden sugar and extra calories.
  • Replacing most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL cholesterol (bad cholesterol) quickly.
  • Foods like avocados, olive oil, fatty fish and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.
  • Quit smoking and avoid excessive intake of alcohol.

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Preva 75 Tablet Substitute

Substitutes safety advice
  • Abclopid 75 Tablet 15's

    7.43per tablet
  • Aquris Clopirel 75 Tablet 10's

    6.65per tablet
  • Clopilet 75 mg Tablet 15's

    6.69per tablet
  • Clopitab Tablet 15's

    6.69per tablet
  • Deplatt 75 mg Tablet 15's

    6.45per tablet
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Alcohol

Caution

You can drink alcohol with Preva 75 Tablet . But do not drink too much while taking this medicine. It can irritate your stomach.

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Pregnancy

Caution

Preva 75 Tablet should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Caution

Preva 75 Tablet should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Safe if prescribed

Preva 75 Tablet has no or negligible influence on the ability to drive or use machines.

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Liver

Safe if prescribed

No dosage adjustment is necessary in patients with liver disease.

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Kidney

Caution

Preva 75 Tablet should be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may have to adjust the dose.

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Children

Unsafe

Preva 75 Tablet is not recommended for children. The safety and effectiveness of Preva 75 Tablet have not been established in children due to limited testing of this drug on children by competent authorities across the world.

FAQs

Preva 75 Tablet is used to prevent heart attack or stroke in people at high risk of heart disease.
Preva 75 Tablet belongs to a class of medications called a blood thinner or an antiplatelet medication. Preva 75 Tablet plays a vital role in preventing the formation of harmful blood clots (plaque) in your veins. It makes blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Preva 75 Tablet helps prevent blood clots if you have an increased risk of having severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).
Yes, Preva 75 Tablet causes blood to thin. It works by preventing platelets (a type of blood cell) from sticking together and forming clots.
Please consult your doctor if Preva 75 Tablet needs to be stopped before undergoing surgery. The doctor might ask you to stop taking Preva 75 Tablet a few days before surgery to avoid the increased risk of bleeding during the procedure.
Do not take aspirin for pain relief or ibuprofen while you are taking Preva 75 Tablet unless your doctor says it's OK. They raise the risk of unusual bleeding.
When a blood clot is treated, guidelines recommend that patients take blood thinners for the rest of their lives. If they do not, the chance of developing a second clot is 30 to 40 per cent in the next 10 years.
There might be a problem if you are taking herbal therapies with Preva 75 Tablet , especially those that affect the blood, like Ginkgo Biloba and St John's wort plant extract used as an antidepressant. Together, taking can increase your risk of bleeding. Tell your doctor if you are using any type of herbal supplements before taking Preva 75 Tablet .
Yes, taking Preva 75 Tablet can increase the risk of bleeding as it contains aspirin, which is a blood thinner. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid any bleeding.
Preva 75 Tablet should be swallowed as a whole with water; do not crush or chew it. Preva 75 Tablet can be taken at any time of the day, but taking it at the same time daily would be better.
Yes, Preva 75 Tablet is a blood thinner. It contains clopidogrel, an antiplatelet medicine that prevents the formation of harmful blood clots.
No, Preva 75 Tablet is not a steroid. It is an antiplatelet medicine.
Preva 75 Tablet might lower the blood pressure. Not everyone experiences this as it is a rare side effect. Consult the doctor if you experience dizziness, blurred vision or light-headedness.
Do not take Preva 75 Tablet if you are allergic to any of its components, have severe liver disease or have a medical condition that causes bleeding such as a stomach ulcer or bleeding within the brain.
You can drink alcohol with Preva 75 Tablet . But do not drink too much alcohol as it can cause stomach irritation.
Avoid taking omeprazole along with Preva 75 Tablet as omeprazole can reduce the levels of clopidogrel and affect its working. Consult the doctor before taking omeprazole with Preva 75 Tablet .
Stopping Preva 75 Tablet may increase the risk of heart attack or stroke. Therefore, do not discontinue Preva 75 Tablet without consulting your doctor.
Preva 75 Tablet starts working within 2 hours of taking it.
Preva 75 Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of treatment based on your condition.
Yes, you can eat food while taking Preva 75 Tablet as it helps lower stomach irritation.
Be cautious while using sharp objects as you may bleed more easily or for a longer time than usual while you are taking Preva 75 Tablet . Let the doctor know that you are taking Preva 75 Tablet if you are due to undergo any surgery or dental procedure.
If you miss a dose of Preva 75 Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Consult the doctor before taking other medicines while on treatment with Preva 75 Tablet . Let the doctor know if you are using anticoagulants, painkillers, antidepressants or indigestion medicines.
Side effects of Preva 75 Tablet include diarrhoea, stomach pain, indigestion, heartburn, headache, nausea, vomiting, constipation, and dizziness. Consult the doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - PRE0096

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