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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Prelo LP Tablet is used to treat hypertension (high blood pressure). It contains Amlodipine and Lisinopril, which relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure. It also improves blood supply to the heart muscle to receive more oxygen and thus preventing chest pain. In some cases, it may cause side effects such as blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache, and swelling of the ankles or feet. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Johnson & Johnson Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Prelo LP Tablet

Prelo LP Tablet is used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against blood vessels' walls. This condition makes the heart work harder to pump blood into the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack, and kidney failure.

Prelo LP Tablet is a combination of medicine that consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine belongs to the class of 'calcium channel blockers and is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure. Amlodipine also improves blood supply to the heart muscle to receive more oxygen, thus preventing chest pain. Lisinopril belongs to the class of 'Angiotensin-Converting Enzyme (ACE) Inhibitors.' It relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure. Lisinopril also decreases the body’s production of certain substances that raise blood pressure.

Prelo LP Tablet is an orally administered drug in the form of a tablet and capsule. You can take Prelo LP Tablet with food or without food. Swallow it as a whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take Prelo LP Tablet based on your medical condition. In some cases, you may experience blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache, and swelling of the ankles or feet. Most of these side effects of Prelo LP Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please contact your doctor.

Do not stop taking Prelo LP Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Regular monitoring of blood pressure, electrolyte levels, and kidney function is advised while taking Prelo LP Tablet . Inform your doctor if you are suffering from kidney, liver or heart diseases. Please tell your doctor if you are taking other medicines or allergic to Prelo LP Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Let your doctor know if you use any prescription and non-prescription medications you are taking, including vitamins, before starting Prelo LP Tablet . If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Prelo LP Tablet can be prescribed accordingly.

Uses of Prelo LP Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Take the tablet with or without food or as directed by your physician. Swallow it with a glass of water. Do not crush, chew, or break it. Try to take it at a fixed time every day. Do not double the dose if missed.

Medicinal Benefits

Prelo LP Tablet treats hypertension (high blood pressure) and consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine is a 'calcium channel blocker' and treats high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure. It also treats chest pain by improving the blood supply to the heart muscle to receive more oxygen. Amlodipine also improves a person's tolerance to exercise and keeps the blood pressure at acceptable levels. Lisinopril is an 'Angiotensin-Converting Enzyme (ACE) Inhibitor.' It relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure.

How Prelo LP Tablet Works

Prelo LP Tablet is a combination of medicine that consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine belongs to the class of 'calcium channel blockers and is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure. Amlodipine also improves blood supply to the heart muscle to receive more oxygen, thus preventing chest pain. Lisinopril belongs to the class of 'Angiotensin-Converting Enzyme (ACE) Inhibitors.' It relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure. Lisinopril also decreases the body’s production of certain substances that raise blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Prelo LP Tablet

  • Confusion
  • Sweating
  • Tiredness
  • Dizziness
  • Headache
  • Blurred vision
  • Stomach upset
  • Swelling of the ankles or feet
  • Flushing (sense of warmth in the face, ears, neck and trunk)

What if I have taken an overdose of Prelo LP Tablet

Do not take more than the prescribed dose of Prelo LP Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Do not use Prelo LP Tablet if you are allergic to Prelo LP Tablet or its components.

  • Please inform your doctor if you are using any prescription and non-prescription medications, including vitamins, before starting Prelo LP Tablet .

  • Let your doctor know if you have any history of severe heart, kidney or liver diseases, high potassium levels (hyperkalaemia), bone marrow suppression, and aortic stenosis (heart valve problem). 

  • It is essential to inform your doctor if you are a breastfeeding mother before using Prelo LP Tablet since Amlodipine may pass into the breast milk.

  • Lisinopril is not recommended during pregnancy since it harms the unborn baby. Please ask your doctor if you plan to conceive or are pregnant before using Prelo LP Tablet .

  • Prelo LP Tablet can increase the chances of light-headedness so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
LisinoprilAliskiren
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Prelo LP Tablet 10's:
Using Prelo LP Tablet 10's together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Prelo LP Tablet 10's with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
LisinoprilAliskiren
Critical
How does the drug interact with Prelo LP Tablet 10's:
Combining Aliskiren with Prelo LP Tablet 10's can increase the potassium levels in the blood.

How to manage the interaction:
Although taking Aliskiren and Prelo LP Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms including weakness, tiredness, confusion, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
AmlodipineTizanidine
Severe
How does the drug interact with Prelo LP Tablet 10's:
Co-administration of Tizanidine and Prelo LP Tablet 10's can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Prelo LP Tablet 10's with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Prelo LP Tablet 10's:
Using Prelo LP Tablet 10's and primidone together may lower Prelo LP Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Prelo LP Tablet 10's with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Prelo LP Tablet 10's:
Coadministration of Prelo LP Tablet 10's and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Prelo LP Tablet 10's together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineMitotane
Severe
How does the drug interact with Prelo LP Tablet 10's:
Using Prelo LP Tablet 10's and mitotane together may drastically lower Prelo LP Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Prelo LP Tablet 10's with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Prelo LP Tablet 10's:
Coadministration of Prelo LP Tablet 10's and Idelalisib may raise Prelo LP Tablet 10's levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Prelo LP Tablet 10's with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipineDolasetron
Severe
How does the drug interact with Prelo LP Tablet 10's:
Using dolasetron together with Prelo LP Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Prelo LP Tablet 10's and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineRifampicin
Severe
How does the drug interact with Prelo LP Tablet 10's:
Coadministration of Prelo LP Tablet 10's and rifampicin together may lower Prelo LP Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Prelo LP Tablet 10's and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Prelo LP Tablet 10's:
Coadministration of Prelo LP Tablet 10's and Rifapentine may significantly reduce the blood levels of Prelo LP Tablet 10's, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Prelo LP Tablet 10's and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+LISINOPRIL-5MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+LISINOPRIL-5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Prelo LP Tablet 10's with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Prelo LP Tablet 10's.

Diet & Lifestyle Advise

  • Keep your weight under control with body mass index (BMI) between 19.5 and 24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm of Hg.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg daily or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, use only one serving for women and two servings for men.
  • Quit smoking to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.
  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.
  • Try including heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Prelo LP Tablet Substitute

Substitutes safety advice
  • Amlopres L Tablet 15's

    13.11per tablet
  • Amlovas-L Tablet 15's

    12.78per tablet
  • Amlace Tablet 10's

    9.90per tablet
  • Amlosafe-LS 5/5 Tablet 10's

    10.98per tablet
  • Amloz L Tablet 15's

    11.40per tablet
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Alcohol

Caution

Alcohol may lower your blood pressure. Limit or avoid consuming alcohol while on treatment with Prelo LP Tablet is advisable.

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Pregnancy

Unsafe

Lisinopril in Prelo LP Tablet is a pregnancy D category drug and is not recommended during pregnancy since it causes harmful effects on the developing foetus. However, it is advised to seek medical advice before using Prelo LP Tablet if you plan to conceive or pregnant.

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Breast Feeding

Caution

There are limited studies on how Prelo LP Tablet affects breastfed infants. However, Amlodipine in Prelo LP Tablet passes into the breast milk during breastfeeding. Please consult your doctor before using Prelo LP Tablet if you are a lactating mother.

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Driving

Caution

Prelo LP Tablet may cause side effects from lowering blood pressure, such as dizziness or tiredness. If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using Prelo LP Tablet . Your doctor may adjust the dose based on your condition.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using Prelo LP Tablet . Prelo LP Tablet is primarily eliminated by the kidney and can be accumulated in patients with renal impairment. Your doctor may adjust the dose based on your condition.

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Children

Unsafe

Prelo LP Tablet is not recommended for children as efficacy and safety have not been established.

FAQs

Prelo LP Tablet is primarily used to treat hypertension (high blood pressure).
Prelo LP Tablet treats hypertension (high blood pressure) and consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine is a 'calcium channel blocker' and treats high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure.
Prelo LP Tablet is recommended to use in dose and duration as advised by the doctor. Do not stop taking Prelo LP Tablet on your own, as it may lead to a sudden rise in blood pressure and increases the risk of heart attack and stroke.
Prelo LP Tablet may increase blood potassium levels in people with diabetes, poor kidney function, and patients using potassium-sparing diuretics or taking potassium supplements. Please consult your doctor before taking Prelo LP Tablet if you have diabetes.
Amlodipine in Prelo LP Tablet can cause ankle swelling upon long-term use. Please try to keep your feet in an elevated position when sitting for long hours. If the problem persists, please consult your doctor and do as advised.
Even though your blood pressure becomes normal after using Prelo LP Tablet , it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule.

Country of origin

India

Manufacturer/Marketer address

BLOCK NO 532 A & B P.O MANJUSAR,TAL-SAVLI VADODARA GJ 391775 IN
Other Info - PRE0307

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