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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Hipril-A Tablet is used to treat hypertension (high blood pressure). It contains Amlodipine and Lisinopril, which relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure. It also improves blood supply to the heart muscle to receive more oxygen and thus preventing chest pain. In some cases, it may cause side effects such as blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache, and swelling of the ankles or feet. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Hipril-A Tablet

Hipril-A Tablet is used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against blood vessels' walls. This condition makes the heart work harder to pump blood into the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack, and kidney failure.

Hipril-A Tablet is a combination of medicine that consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine belongs to the class of 'calcium channel blockers and is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure. Amlodipine also improves blood supply to the heart muscle to receive more oxygen, thus preventing chest pain. Lisinopril belongs to the class of 'Angiotensin-Converting Enzyme (ACE) Inhibitors.' It relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure. Lisinopril also decreases the body’s production of certain substances that raise blood pressure.

Hipril-A Tablet is an orally administered drug in the form of a tablet and capsule. You can take Hipril-A Tablet with food or without food. Swallow it as a whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take Hipril-A Tablet based on your medical condition. In some cases, you may experience blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache, and swelling of the ankles or feet. Most of these side effects of Hipril-A Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please contact your doctor.

Do not stop taking Hipril-A Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Regular monitoring of blood pressure, electrolyte levels, and kidney function is advised while taking Hipril-A Tablet . Inform your doctor if you are suffering from kidney, liver or heart diseases. Please tell your doctor if you are taking other medicines or allergic to Hipril-A Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Let your doctor know if you use any prescription and non-prescription medications you are taking, including vitamins, before starting Hipril-A Tablet . If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Hipril-A Tablet can be prescribed accordingly.

Uses of Hipril-A Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Take the tablet with or without food or as directed by your physician. Swallow it with a glass of water. Do not crush, chew, or break it. Try to take it at a fixed time every day. Do not double the dose if missed.

Medicinal Benefits

Hipril-A Tablet treats hypertension (high blood pressure) and consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine is a 'calcium channel blocker' and treats high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure. It also treats chest pain by improving the blood supply to the heart muscle to receive more oxygen. Amlodipine also improves a person's tolerance to exercise and keeps the blood pressure at acceptable levels. Lisinopril is an 'Angiotensin-Converting Enzyme (ACE) Inhibitor.' It relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure.

How Hipril-A Tablet Works

Hipril-A Tablet is a combination of medicine that consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine belongs to the class of 'calcium channel blockers and is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure. Amlodipine also improves blood supply to the heart muscle to receive more oxygen, thus preventing chest pain. Lisinopril belongs to the class of 'Angiotensin-Converting Enzyme (ACE) Inhibitors.' It relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure. Lisinopril also decreases the body’s production of certain substances that raise blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Hipril-A Tablet

  • Confusion
  • Sweating
  • Tiredness
  • Dizziness
  • Headache
  • Blurred vision
  • Stomach upset
  • Swelling of the ankles or feet
  • Flushing (sense of warmth in the face, ears, neck and trunk)

What if I have taken an overdose of Hipril-A Tablet

Do not take more than the prescribed dose of Hipril-A Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Do not use Hipril-A Tablet if you are allergic to Hipril-A Tablet or its components.

  • Please inform your doctor if you are using any prescription and non-prescription medications, including vitamins, before starting Hipril-A Tablet .

  • Let your doctor know if you have any history of severe heart, kidney or liver diseases, high potassium levels (hyperkalaemia), bone marrow suppression, and aortic stenosis (heart valve problem). 

  • It is essential to inform your doctor if you are a breastfeeding mother before using Hipril-A Tablet since Amlodipine may pass into the breast milk.

  • Lisinopril is not recommended during pregnancy since it harms the unborn baby. Please ask your doctor if you plan to conceive or are pregnant before using Hipril-A Tablet .

  • Hipril-A Tablet can increase the chances of light-headedness so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
LisinoprilAliskiren
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Hipril-A Tablet 10's:
Using Hipril-A Tablet 10's together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Hipril-A Tablet 10's with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
LisinoprilAliskiren
Critical
How does the drug interact with Hipril-A Tablet 10's:
Combining Aliskiren with Hipril-A Tablet 10's can increase the potassium levels in the blood.

How to manage the interaction:
Although taking Aliskiren and Hipril-A Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms including weakness, tiredness, confusion, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
AmlodipinePrimidone
Severe
How does the drug interact with Hipril-A Tablet 10's:
Using Hipril-A Tablet 10's and primidone together may lower Hipril-A Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Hipril-A Tablet 10's with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineDolasetron
Severe
How does the drug interact with Hipril-A Tablet 10's:
Using dolasetron together with Hipril-A Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Hipril-A Tablet 10's and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineRifapentine
Severe
How does the drug interact with Hipril-A Tablet 10's:
Coadministration of Hipril-A Tablet 10's and Rifapentine may significantly reduce the blood levels of Hipril-A Tablet 10's, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Hipril-A Tablet 10's and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipinePhenytoin
Severe
How does the drug interact with Hipril-A Tablet 10's:
Using Hipril-A Tablet 10's and phenytoin together may drastically lower Hipril-A Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Hipril-A Tablet 10's with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineEnzalutamide
Severe
How does the drug interact with Hipril-A Tablet 10's:
Using a combination of Hipril-A Tablet 10's and enzalutamide may drastically lower Hipril-A Tablet 10's blood levels, making the medicine less effective.

How to manage the interaction:
Taking Hipril-A Tablet 10's with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineCeritinib
Severe
How does the drug interact with Hipril-A Tablet 10's:
Coadministration of Ceritinib together with Hipril-A Tablet 10's can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Hipril-A Tablet 10's with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineRifampicin
Severe
How does the drug interact with Hipril-A Tablet 10's:
Coadministration of Hipril-A Tablet 10's and rifampicin together may lower Hipril-A Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Hipril-A Tablet 10's and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Hipril-A Tablet 10's:
Coadministration of Hipril-A Tablet 10's and Idelalisib may raise Hipril-A Tablet 10's levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Hipril-A Tablet 10's with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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AMLODIPINE-5MG+LISINOPRIL-5MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+LISINOPRIL-5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Hipril-A Tablet 10's with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Hipril-A Tablet 10's.

Diet & Lifestyle Advise

  • Keep your weight under control with body mass index (BMI) between 19.5 and 24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm of Hg.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg daily or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, use only one serving for women and two servings for men.
  • Quit smoking to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.
  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.
  • Try including heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Hipril-A Tablet Substitute

Substitutes safety advice
  • Amlopres L Tablet 15's

    13.11per tablet
  • Amlovas-L Tablet 15's

    12.78per tablet
  • Amlace Tablet 10's

    9.90per tablet
  • Amlosafe-LS 5/5 Tablet 10's

    10.98per tablet
  • Amloz L Tablet 15's

    11.40per tablet
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Alcohol

Caution

Alcohol may lower your blood pressure. Limit or avoid consuming alcohol while on treatment with Hipril-A Tablet is advisable.

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Pregnancy

Unsafe

Lisinopril in Hipril-A Tablet is a pregnancy D category drug and is not recommended during pregnancy since it causes harmful effects on the developing foetus. However, it is advised to seek medical advice before using Hipril-A Tablet if you plan to conceive or pregnant.

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Breast Feeding

Caution

There are limited studies on how Hipril-A Tablet affects breastfed infants. However, Amlodipine in Hipril-A Tablet passes into the breast milk during breastfeeding. Please consult your doctor before using Hipril-A Tablet if you are a lactating mother.

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Driving

Caution

Hipril-A Tablet may cause side effects from lowering blood pressure, such as dizziness or tiredness. If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using Hipril-A Tablet . Your doctor may adjust the dose based on your condition.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using Hipril-A Tablet . Hipril-A Tablet is primarily eliminated by the kidney and can be accumulated in patients with renal impairment. Your doctor may adjust the dose based on your condition.

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Children

Unsafe

Hipril-A Tablet is not recommended for children as efficacy and safety have not been established.

FAQs

Hipril-A Tablet is primarily used to treat hypertension (high blood pressure).
Hipril-A Tablet treats hypertension (high blood pressure) and consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine is a 'calcium channel blocker' and treats high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure.
Hipril-A Tablet is recommended to use in dose and duration as advised by the doctor. Do not stop taking Hipril-A Tablet on your own, as it may lead to a sudden rise in blood pressure and increases the risk of heart attack and stroke.
Hipril-A Tablet may increase blood potassium levels in people with diabetes, poor kidney function, and patients using potassium-sparing diuretics or taking potassium supplements. Please consult your doctor before taking Hipril-A Tablet if you have diabetes.
Amlodipine in Hipril-A Tablet can cause ankle swelling upon long-term use. Please try to keep your feet in an elevated position when sitting for long hours. If the problem persists, please consult your doctor and do as advised.
Even though your blood pressure becomes normal after using Hipril-A Tablet , it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule.

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - HIP0007

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