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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pobix 500k Units Injection is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Pobix 500k Units Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Whats That

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Synonym :

POLYMYXIN B SULPHATE

Manufacturer/Marketer :

Concord Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Pobix 500k Units Injection

Pobix 500k Units Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms.

Pobix 500k Units Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

In some cases, Pobix 500k Units Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Pobix 500k Units Injection. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Pobix 500k Units Injection

Treatment of Bacterial infections

Directions for Use

Pobix 500k Units Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Pobix 500k Units Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. Pobix 500k Units Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

How Pobix 500k Units Injection Works

Pobix 500k Units Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pobix 500k Units Injection

  • Flushing
  • Diarrhoea
  • Dizziness
  • Pain at the injection site

What if I have taken an overdose of Pobix 500k Units Injection

As Pobix 500k Units Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not receive Pobix 500k Units Injection if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Seek medical attention if you experience symptoms of kidney problems (unable to pass urine, change in how much urine you pass), nerve problems (weakness, irritation, feeling sleepy, blurred eyesight, change in balance, numbness or tingling around the mouth or in the arms or legs, or trouble breathing), or Clostridium difficile associated diarrhoea/CDAD (stomach pain, cramps, very loose, watery, or bloody stool). Let the doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

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Polymyxin bNetilmicin
Severe
Polymyxin bHuman immunoglobulin
Severe

Drug-Drug Interactions

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Polymyxin bNetilmicin
Severe
How does the drug interact with Pobix 500k Units Injection:
Co-administration of Netilmicin with Pobix 500k Units Injection can increase the risk of side effects.

How to manage the interaction:
Co-administration of Netilmicin with Pobix 500k Units Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bHuman immunoglobulin
Severe
How does the drug interact with Pobix 500k Units Injection:
Taking Human immunoglobulin with Polymyxin- b, may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Pobix 500k Units Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Polymyxin bNeomycin
Severe
How does the drug interact with Pobix 500k Units Injection:
When Neomycin and Pobix 500k Units Injection are taken together, there is an increased possibility of severe side effects.

How to manage the interaction:
Taking Pobix 500k Units Injection with Neomycin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bAmikacin
Severe
How does the drug interact with Pobix 500k Units Injection:
Coadministration of Amikacin with Pobix 500k Units Injection may increase the risk of severe side effects.

How to manage the interaction:
Although taking Amikacin and Polymyxin- b together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience ringing in the ears, difficulty breathing, vomiting, irregular urination, swelling, muscle pain, dizziness, or palpitation. Do not stop using any medications without talking to a doctor.
Polymyxin bTobramycin
Severe
How does the drug interact with Pobix 500k Units Injection:
Taking Tobramycin with Pobix 500k Units Injection can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobramycin and Pobix 500k Units Injection, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Polymyxin bTenofovir disoproxil
Severe
How does the drug interact with Pobix 500k Units Injection:
Coadministration of Tenofovir disoproxil with Pobix 500k Units Injection can increase the risk of side effects.

How to manage the interaction:
Taking Tenofovir disoproxil with Pobix 500k Units Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
Polymyxin bKanamycin
Severe
How does the drug interact with Pobix 500k Units Injection:
Taking Kanamycin with Pobix 500k Units Injection can increase the risk and severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Pobix 500k Units Injection and Kanamycin, but it can be taken if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bCidofovir
Severe
How does the drug interact with Pobix 500k Units Injection:
Taking Cidofovir with Pobix 500k Units Injection sulfate can increase the risk of kidney problems.

How to manage the interaction:
Although taking Polymyxin-b and Cidofovir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, swelling, breathing difficulty, bone pain, muscle pain, dizziness, confusion, or irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
Polymyxin bStreptomycin
Severe
How does the drug interact with Pobix 500k Units Injection:
Using Pobix 500k Units Injection together with streptomycin can increase the risk or severity of developing hearing loss, breathing problems, and kidney problems.

How to manage the interaction:
Although taking Pobix 500k Units Injection and Streptomycin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medication without consulting a doctor.
Polymyxin bIodamide
Severe
How does the drug interact with Pobix 500k Units Injection:
Co-administration of Iodamide with Pobix 500k Units Injection may increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Pobix 500k Units Injection and Iodamide, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotic treatment and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Pobix 500k Units Injection Substitute

Substitutes safety advice
  • Poly-B 500000IU Injection 1's

    2446.70per tablet
  • POLY MX B 500000IU INJECTION

    2549.30per tablet
  • Unipol-B Injection 1'S

    by AYUR

    1790.10per tablet
  • Polytuff 500000units Injection

    by AYUR

    3339.90per tablet
  • PAXY B 500000IU INJECTION

    2784.20per tablet
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Pobix 500k Units Injection. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Pobix 500k Units Injection.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Pobix 500k Units Injection. Caution is advised while administering Pobix 500k Units Injection to lactating women.

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Driving

Consult your doctor

It is unknown if Pobix 500k Units Injection affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Pobix 500k Units Injection.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Pobix 500k Units Injection.

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Children

Safe if prescribed

Pobix 500k Units Injection may be safe for use in children if prescribed by the doctor.

FAQs

Pobix 500k Units Injection is used to treat Bacterial infections.
Pobix 500k Units Injection works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.
Diarrhoea might be a side effect of Pobix 500k Units Injection. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the condition persists or worsens.
Pobix 500k Units Injection may cause nerve problems. Consult the doctor if you experience weakness, irritation, change in balance, feeling sleepy, blurred eyesight, trouble breathing, numbness or tingling sensation in the arms and legs.
Pobix 500k Units Injection will be administered by a healthcare professional. Do not self-administer.
Yes, Pobix 500k Units Injection is safe when used only under the doctor’s supervision. However, it may cause pain at the injection site, flushing, dizziness, and diarrhoea while using it.
The common side effects of Pobix 500k Units Injection may include pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Survey No: 249, Brahmanapally(V), Hayathnagar(M),R.R.District, Hyderabad, Telangana, INDIA – 501511
Other Info - POB0001

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