Pletoz 50 Tablet contains vasodilator (blood vessel widening) medication, Cilostazole, which is primarily used to treat pain in the legs due to insufficient blood flow (intermittent claudication). It also reduces cramping, numbness or weakness in the legs on walking in such patients. Intermittent claudication is a peripheral vascular disease in which you have cramp-like pain in your legs when you walk and is caused by an insufficient blood supply in your legs.

Pletoz 50 Tablet works by widening the blood vessels and reducing the blood clotting time, thereby decreasing stickiness in blood vessels. Hence, increasing the blood supply to the limbs. It can also increase the distance you can walk without pain since it improves your leg's blood circulation. It is recommended in patients whose pain has not improved even after lifestyle changes like quitting smoking and doing regular exercise.

Pletoz 50 Tablet should be taken regularly in dose and duration as advised by the doctor. It would be best to take it on an empty stomach and at a fixed time every day. Your doctor will advise you on the exact dosage and how often you must take Pletoz 50 Tablet based on your medical condition. In some cases, you may experience headaches, ankle swelling, diarrhoea, abnormal stools, vomiting, and nausea. Most of these side effects of Pletoz 50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Pletoz 50 Tablet should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side effects. Also, it is not suitable for some people. Inform your doctor before starting Pletoz 50 Tablet if you have any kidney or liver disease, plan to become pregnant, or are breastfeeding. Also, lifestyle changes should be continued with Pletoz 50 Tablet for best results. Do not take the Pletoz 50 Tablet if you ever had heart failure, chest pain, heart disease, and blood pressure. Before taking the Pletoz 50 Tablet , inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Pletoz 50 Tablet contains, Cilostazole, which is a vasodilator that works by widening the blood vessel and reducing the blood clotting time, thereby decreasing stickiness in blood vessels. Hence, increasing the blood supply to the limbs. It can also increase the distance you can walk without pain since it improves your legs' blood circulation. It is recommended in patients whose pain has not improved even after lifestyle changes like quitting smoking and doing regular exercise.

• Headaches

• Ankle swelling

• Diarrhoea

• Abnormal stools

• Vomiting

• Nausea

Pletoz 50 Tablet should not be given to the people allergic to Pletoz 50 Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Do not take Pletoz 50 Tablet with grapefruit juice or St John wort plant as it might affect the absorption of Pletoz 50 Tablet .  Tell your doctor that you are using Pletoz 50 Tablet before undergoing any dental or other surgery. Your doctor might stop this medicine before the surgery. It is best to take Pletoz 50 Tablet on an empty stomach and at a fixed time every day. Pletoz 50 Tablet should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side effects. Also, lifestyle changes should be continued with Pletoz 50 Tablet for best results and a speedy recovery.

Drug-Drug Interactions: Pletoz 50 Tablet interacts with some medicines, so it should be used with caution with blood thinners (rivaroxaban, aspirin), antibiotics (erythromycin, clarithromycin or rifampicin), anti-fungal  (ketoconazole), anti-hypertensive (diltiazem, lovastatin, simvastatin, atorvastatin),  anti-migraine (ergotamine, dihydroergotamine), sedatives or hypnotics (buspirone), certain antidepressants (fluoxetine and lithium), medicines to lower blood pressure (methyldopa), anti-Parkinson’s (levodopa, pramipexole, ropinirole), anti-epilepsy (phenobarbital, carbamazepine, phenytoin, rifampicin, primidone, oxcarbazepine, ethosuximide, valproate).

Drug-Food Interactions: Grapefruit juice intake and St. John’s wort (An herbal remedy for depression) should be avoided with Pletoz 50 Tablet as it may interact with Pletoz 50 Tablet to produce unpleasant side effects.

Drug-Disease Interactions: Pletoz 50 Tablet should be taken with caution in people with a bleeding problem, have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women.

• ERYTHROMYCIN
• CLARITHROMYCIN
• RIFAMPICIN
• DILTIAZEM
• SIMVASTATIN
• BUSPIRONE
• LEVODOPA
• VALPROATE

• Exercising regularly helps in improving overall health. Take a break between exercises if you feel uneasy. Finding the right exercise is the key.

• Rest well, and get plenty of sleep.

• Take proper care of your legs and feet.

• Wear shoes that fit you well.

• Check your feet daily for any cracks or sores.

• Try to stay warm. Avoid cold temperatures.

• Avoid smoking and alcohol consumption.

• Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

• Acupuncture can be helpful by stimulating pressure points.

• Using essential oils for massages can help increase circulation.

Intermittent claudication: Intermittent claudication, also known as vascular claudication, is a symptom in which muscle pain or mild exertion occurs during exercise. The pain is generally felt in the calf muscle. Symptoms include cramp, ache, fatigue, and numbness.