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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Pirox 10 mg Capsule is used to relieve symptoms like pain, inflammation and joint stiffness associated with rheumatoid arthritis and osteoarthritis. It contains Piroxicam, which stops the production of prostaglandins (chemicals) that are produced at injury sites and cause pain and swelling. In some cases, you may experience certain common side effects, such as diarrhoea, dizziness, nausea, vomiting, and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

PIROXICAM-10MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Pirox 10 mg Capsule

Pirox 10 mg Capsule used to relieve symptoms like pain, inflammation and joint stiffness associated with rheumatoid arthritis and osteoarthritis. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage.

Pirox 10 mg Capsule contains 'Piroxicam' that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Take Pirox 10 mg Capsule as prescribed. In some cases, you may experience certain common side effects, such as diarrhoea, dizziness, nausea, vomiting, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.

Pirox 10 mg Capsule can increase your risk of a fatal heart attack or stroke. So, if you have had any recent heart bypass surgery, do not take Pirox 10 mg Capsule unless prescribed by the doctor. Pirox 10 mg Capsule increases the chances of stomach ulcers and bleeding. Consult your doctor before taking Pirox 10 mg Capsule if you are pregnant or breastfeeding. Pirox 10 mg Capsule may cause dizziness, so drive with caution. Pirox 10 mg Capsule is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Pirox 10 mg Capsule as it could lead to increased dizziness. It could also increase the risk of stomach bleeding.

Uses of Pirox 10 mg Capsule

Treatment of Osteoarthritis, Rheumatoid arthritis.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not chew, break, or crush the tablet/capsule.Dispersible tablet: Disperse the tablet in boiled and cooled water, stir well and consume immediately.

Medicinal Benefits

Pirox 10 mg Capsule belongs to the group of painkillers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Pirox 10 mg Capsule is used to relieve symptoms associated with osteoarthritis, and rheumatoid arthritis, such as stiffness, swelling, and joint pain. Pirox 10 mg Capsule works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

How Pirox 10 mg Capsule Works

Pirox 10 mg Capsule contains 'Piroxicam' that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pirox 10 mg Capsule

  • Diarrhoea
  • Dizziness
  • Nausea
  • Vomiting
  • Stomach pain

What if I have taken an overdose of Pirox 10 mg Capsule

Do not take more than the prescribed dose of Pirox 10 mg Capsule as it may cause overdose. The symptoms of overdose include drowsiness, lack of energy, vomiting, stomach upset, bloody/black/tarry stools, stomach pain, dificulty breathing, or coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Pirox 10 mg Capsule may increase the risk of serious heart-related problems, like heart attack and stroke. So, if you are a heart patient, let your doctor know before taking Pirox 10 mg Capsule . Besides this, Pirox 10 mg Capsule may also cause stomach and intestinal bleeding/ulcers, so let your doctor know if you have these problems. Do not take Pirox 10 mg Capsule if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG) as it can increase your risk of a heart attack or stroke. Consult your doctor before taking Pirox 10 mg Capsule if you are pregnant or breastfeeding. Pirox 10 mg Capsule may cause drowsiness and dizziness, so drive only if you are alert. Pirox 10 mg Capsule is not recommended for children as safety has not been established. Avoid consuming alcohol along with Pirox 10 mg Capsule as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Tell your doctor before taking Pirox 10 mg Capsule if you have asthma, water retention (oedema) or high blood pressure, stuff/runny nose, nasal polyps, liver or kidney problems.

Drug-Drug Interactions

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PiroxicamKetorolac tromethamine
Critical
PiroxicamCidofovir
Critical

Drug-Drug Interactions

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PiroxicamKetorolac tromethamine
Critical
How does the drug interact with Pirox 10 mg Capsule 10's:
Using ketorolac tromethamine together with Pirox 10 mg Capsule 10's may increase the risk of side effects.

How to manage the interaction:
Taking Pirox 10 mg Capsule 10's with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
PiroxicamCidofovir
Critical
How does the drug interact with Pirox 10 mg Capsule 10's:
Co-administration of Cidofovir with Pirox 10 mg Capsule 10's can increase the risk of kidney problems.

How to manage the interaction:
Taking Pirox 10 mg Capsule 10's with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamNabumetone
Severe
How does the drug interact with Pirox 10 mg Capsule 10's:
Coadministration of Nabumetone with Pirox 10 mg Capsule 10's can increase the risk of side effects inflammation(swelling with redness and pain), bleeding, ulceration, and perforation.

How to manage the interaction:
Co-administration of Pirox 10 mg Capsule 10's with Nabumetone can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamApixaban
Severe
How does the drug interact with Pirox 10 mg Capsule 10's:
Coadministration of Pirox 10 mg Capsule 10's and Apixaban may raise the risk of bleeding.

How to manage the interaction:
Combination of Pirox 10 mg Capsule 10's and Apixaban may cause an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
PiroxicamPerindopril
Severe
How does the drug interact with Pirox 10 mg Capsule 10's:
Using perindopril together with Pirox 10 mg Capsule 10's may reduce the effects of perindopril in lowering blood pressure, they may also increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Pirox 10 mg Capsule 10's with Perindopril can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, and irregular heart rhythm, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
PiroxicamAcalabrutinib
Severe
How does the drug interact with Pirox 10 mg Capsule 10's:
Using acalabrutinib together with Pirox 10 mg Capsule 10's may increase the risk of bleeding.

How to manage the interaction:
Although taking Pirox 10 mg Capsule 10's and Acalabrutinib together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamFenoprofen
Severe
How does the drug interact with Pirox 10 mg Capsule 10's:
Coadministration of Pirox 10 mg Capsule 10's with Fenoprofen can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Taking Pirox 10 mg Capsule 10's with Fenoprofen together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamDesirudin
Severe
How does the drug interact with Pirox 10 mg Capsule 10's:
Taking Pirox 10 mg Capsule 10's with Desirudin together can increase the risk of bleeding.

How to manage the interaction:
Taking Pirox 10 mg Capsule 10's with Desirudin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamDanaparoid
Severe
How does the drug interact with Pirox 10 mg Capsule 10's:
Coadministration of Pirox 10 mg Capsule 10's with Danaparoid can increase the risk of bleeding.

How to manage the interaction:
Although taking Pirox 10 mg Capsule 10's and Danaparoid together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamTinzaparin
Severe
How does the drug interact with Pirox 10 mg Capsule 10's:
Coadministration of Pirox 10 mg Capsule 10's with Tinzaparin can increase the risk of bleeding.

How to manage the interaction:
Taking Pirox 10 mg Capsule 10's with Tinzaparin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience headache, dizziness, weakness, unexpected bruising or bleeding, swelling, vomiting, blood in your stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.

  • Acupuncture, massage, and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Pirox 10 mg Capsule Substitute

Substitutes safety advice
  • Ugesic 10 mg Tablet 10's

    13.50per tablet
  • BREXIC INJECTION 2ML

    61.65per tablet
  • Greatin Tablet 28's

    by AYUR

    33.75per tablet
  • Alkem Piroxicam 10mg Tablet DT

    3.60per tablet
  • Plexus 10mg Injection

    25.20per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Pirox 10 mg Capsule . Alcohol intake, along Pirox 10 mg Capsule may cause increased dizziness. It may also cause an increase in the risk of stomach/intestine ulcers and bleeding.

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Pregnancy

Caution

Avoid taking Pirox 10 mg Capsule if you are pregnant unless prescribed by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe Pirox 10 mg Capsule only if the benefits outweigh the risks. Do not take Pirox 10 mg Capsule in the last 20 weeks of pregnancy as it may cause serious kidney and heart problems in the unborn baby and complications with the pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Pirox 10 mg Capsule . Please consult your doctor if you have any concerns.

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Driving

Caution

Pirox 10 mg Capsule may cause dizziness. Do not drive or operate heavy machinery if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed. Pirox 10 mg Capsule should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Pirox 10 mg Capsule should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pirox 10 mg Capsule is not recommended for children, as the efficacy and safety have not been established.

FAQs

Pirox 10 mg Capsule is used to relieve symptoms like pain, inflammation and joint stiffness associated with rheumatoid arthritis and osteoarthritis.
Pirox 10 mg Capsule works by blocking the effect of chemical messengers (prostaglandin), thereby reducing joint pain, stiffness, swelling, and inflammation.
Diarrhoea might be a side-effect of Pirox 10 mg Capsule . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Do not take Pirox 10 mg Capsule for longer durations or high doses as it may cause unpleasant side effects. Do not exceed the dose and duration prescribed by your doctor.
Pirox 10 mg Capsule may increase the risk of heart attack or stroke. Do not use Pirox 10 mg Capsule immediately before or after bypass surgery. Inform your doctor if you have heart problems.
Consult your doctor before taking Pirox 10 mg Capsule if you have diabetes as Pirox 10 mg Capsule might increase the blood sugar levels.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - PIR0013

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