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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
BREXIC INJECTION 2ML contains piroxicam which is an NSAID (Non-Steroidal Anti-Inflammatory Drugs) medicine. It is mainly used to relieve pain, swelling, and stiffness caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis (inflammation of the joints). It is sometimes also used to reduce back pain. This medicine inhibits cyclo-oxygenase (COX) enzymes and this helps reduce pain.
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Composition :

PIROXICAM-10MG

Manufacturer/Marketer :

Wockhardt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About BREXIC INJECTION 2ML

BREXIC INJECTION 2ML belongs to the group of medications known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms like pain and inflammation associated with rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage.

BREXIC INJECTION 2ML contains 'Piroxicam' that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at the injury site and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

BREXIC INJECTION 2ML will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as injection site reactions, diarrhoea, dizziness, nausea, vomiting, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.

BREXIC INJECTION 2ML may increase the risk of heart attack and the chances of stomach ulcers and bleeding. If you have had any recent heart bypass surgery, do not take BREXIC INJECTION 2ML unless prescribed by the doctor. Consult your doctor before taking BREXIC INJECTION 2ML if you are pregnant or breastfeeding. BREXIC INJECTION 2ML may cause dizziness, so drive with caution. BREXIC INJECTION 2ML is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with BREXIC INJECTION 2ML as it could lead to increased drowsiness and dizziness. It could also increase the risk of stomach bleeding.

Uses of BREXIC INJECTION 2ML

Treatment of Musculoskeletal pain, Osteoarthritis and Rheumatoid arthritis

Directions for Use

BREXIC INJECTION 2ML will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

BREXIC INJECTION 2ML belongs to the group of pain killers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to treat musculoskeletal pain. It is also used to relieve symptoms associated with osteoarthritis, and rheumatoid arthritis, such as stiffness, swelling, and joint pain. BREXIC INJECTION 2ML works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at the injury site and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

How BREXIC INJECTION 2ML Works

BREXIC INJECTION 2ML contains 'Piroxicam' that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at the injury site and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight

Side Effects of BREXIC INJECTION 2ML

  • Injection site reactions
  • Diarrhoea
  • Dizziness
  • Nausea
  • Vomiting
  • Stomach pain

What if I have taken an overdose of BREXIC INJECTION 2ML

A healthcare professional administers BREXIC INJECTION 2ML as per the prescribed dosage schedule. Hence, the chances of overdose are less. Overdose may cause a lack of energy, drowsiness, upset stomach, vomiting, stomach pain, bloody, black, or tarry stools, vomiting a substance that is bloody or looks like coffee grounds, and difficulty breathing. Your doctor may initiate the necessary treatment if an overdose is suspected.

Drug Warnings

BREXIC INJECTION 2ML may increase the risk of serious heart-related problems, like heart attack and stroke. So, if you are a heart patient, let your doctor know before taking BREXIC INJECTION 2ML. Besides this, BREXIC INJECTION 2ML may also cause stomach and intestinal bleeding/ulcers, so let your doctor know if you have these problems. Do not take BREXIC INJECTION 2ML if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG) as it can increase the risk of a heart attack. Consult your doctor before taking BREXIC INJECTION 2ML if you are pregnant or breastfeeding. BREXIC INJECTION 2ML may cause dizziness, so drive only if you are alert. BREXIC INJECTION 2ML is not recommended for children as safety has not been established. Avoid consuming alcohol along with BREXIC INJECTION 2ML as it could lead to increased dizziness and may increase the risk of stomach bleeding. Inform your doctor before taking BREXIC INJECTION 2ML if you have asthma, water retention (oedema) or high blood pressure, stuffy/runny nose, nasal polyps, liver or kidney problems.

Drug-Drug Interactions

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PiroxicamKetorolac tromethamine
Critical
PiroxicamCidofovir
Critical

Drug-Drug Interactions

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PiroxicamKetorolac tromethamine
Critical
How does the drug interact with BREXIC INJECTION 2ML:
Using ketorolac tromethamine together with BREXIC INJECTION 2ML may increase the risk of side effects.

How to manage the interaction:
Taking BREXIC INJECTION 2ML with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
PiroxicamCidofovir
Critical
How does the drug interact with BREXIC INJECTION 2ML:
Co-administration of Cidofovir with BREXIC INJECTION 2ML can increase the risk of kidney problems.

How to manage the interaction:
Taking BREXIC INJECTION 2ML with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamNabumetone
Severe
How does the drug interact with BREXIC INJECTION 2ML:
Coadministration of Nabumetone with BREXIC INJECTION 2ML can increase the risk of side effects inflammation(swelling with redness and pain), bleeding, ulceration, and perforation.

How to manage the interaction:
Co-administration of BREXIC INJECTION 2ML with Nabumetone can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamApixaban
Severe
How does the drug interact with BREXIC INJECTION 2ML:
Coadministration of BREXIC INJECTION 2ML and Apixaban may raise the risk of bleeding.

How to manage the interaction:
Combination of BREXIC INJECTION 2ML and Apixaban may cause an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
PiroxicamPerindopril
Severe
How does the drug interact with BREXIC INJECTION 2ML:
Using perindopril together with BREXIC INJECTION 2ML may reduce the effects of perindopril in lowering blood pressure, they may also increase the risk of kidney problems.

How to manage the interaction:
Co-administration of BREXIC INJECTION 2ML with Perindopril can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, and irregular heart rhythm, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
PiroxicamAcalabrutinib
Severe
How does the drug interact with BREXIC INJECTION 2ML:
Using acalabrutinib together with BREXIC INJECTION 2ML may increase the risk of bleeding.

How to manage the interaction:
Although taking BREXIC INJECTION 2ML and Acalabrutinib together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamFenoprofen
Severe
How does the drug interact with BREXIC INJECTION 2ML:
Coadministration of BREXIC INJECTION 2ML with Fenoprofen can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Taking BREXIC INJECTION 2ML with Fenoprofen together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamDesirudin
Severe
How does the drug interact with BREXIC INJECTION 2ML:
Taking BREXIC INJECTION 2ML with Desirudin together can increase the risk of bleeding.

How to manage the interaction:
Taking BREXIC INJECTION 2ML with Desirudin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamDanaparoid
Severe
How does the drug interact with BREXIC INJECTION 2ML:
Coadministration of BREXIC INJECTION 2ML with Danaparoid can increase the risk of bleeding.

How to manage the interaction:
Although taking BREXIC INJECTION 2ML and Danaparoid together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamTinzaparin
Severe
How does the drug interact with BREXIC INJECTION 2ML:
Coadministration of BREXIC INJECTION 2ML with Tinzaparin can increase the risk of bleeding.

How to manage the interaction:
Taking BREXIC INJECTION 2ML with Tinzaparin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience headache, dizziness, weakness, unexpected bruising or bleeding, swelling, vomiting, blood in your stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

BREXIC INJECTION 2ML Substitute

Substitutes safety advice
  • Ugesic 10 mg Tablet 10's

    13.50per tablet
  • Greatin Tablet 28's

    by AYUR

    33.75per tablet
  • Pirox 10 mg Capsule 10's

    5.85per tablet
  • Plexus 10mg Injection

    25.20per tablet
  • Alkem Piroxicam 10mg Tablet DT

    3.60per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking BREXIC INJECTION 2ML. Alcohol intake, along with BREXIC INJECTION 2ML, may cause increased dizziness. It may also increase the risk of stomach/intestine ulcers and bleeding.

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Pregnancy

Caution

Avoid taking BREXIC INJECTION 2ML if you are pregnant unless prescribed by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe BREXIC INJECTION 2ML only if the benefits outweigh the risks. Do not take BREXIC INJECTION 2ML in the last 20 weeks of pregnancy as it may cause serious kidney and heart problems in the unborn baby and complications with the pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking BREXIC INJECTION 2ML. Please consult your doctor if you have any concerns.

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Driving

Caution

BREXIC INJECTION 2ML may cause dizziness. Do not drive or operate heavy machinery if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed. BREXIC INJECTION 2ML should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. BREXIC INJECTION 2ML should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

BREXIC INJECTION 2ML is not recommended for children, as the efficacy and safety have not been established.

FAQs

BREXIC INJECTION 2ML belongs to the group of medications known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms like pain and inflammation associated with rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders.
BREXIC INJECTION 2ML works by blocking the effect of chemical messengers (prostaglandin), thereby reducing pain, stiffness, swelling, and inflammation.
Diarrhoea might be a side-effect of BREXIC INJECTION 2ML. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Do not use BREXIC INJECTION 2ML immediately before or after bypass surgery. BREXIC INJECTION 2ML may increase the risk of heart attack or stroke. Therefore, inform your doctor if you have heart problems.
BREXIC INJECTION 2ML may be used to treat musculoskeletal pain. Musculoskeletal pain refers to the pain in the bones, muscles, ligaments, and tendon.

Country of origin

India

Manufacturer/Marketer address

Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India
Other Info - BRE0033

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