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Pexep CR 12.5 Tablet 15's

Pexep CR 12.5 Tablet 15's

Prescription drug
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Consult Doctor

Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Pexep CR 12.5 Tablet

Pexep CR 12.5 Tablet belongs to a group of medicines called antidepressants used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoria disorder and generalised anxiety disorder. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.

Pexep CR 12.5 Tablet contains ‘Paroxetine’, which is a selective serotonin reuptake inhibitor. It works by inhibiting serotonin's reuptake, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders.

Take Pexep CR 12.5 Tablet as prescribed. You are advised to take Pexep CR 12.5 Tablet for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as insomnia (difficulty sleeping), dizziness, headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and sexual disturbances. You are advised to talk to your doctor if the side effects persist or worsen.

Do not take Pexep CR 12.5 Tablet if you are pregnant, as it may cause harm to the foetus. Consult your doctor before taking Pexep CR 12.5 Tablet if you are breastfeeding. Avoid driving or operating machinery as Pexep CR 12.5 Tablet may cause dizziness, confusion, sleepiness and blurred vision. Pexep CR 12.5 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Avoid consumption of alcohol while taking Pexep CR 12.5 Tablet as it may make your symptoms or side-effects worse. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Pexep CR 12.5 Tablet

Treatment of Major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.

Medicinal Benefits

Pexep CR 12.5 Tablet belongs to a group of antidepressant medicines called selective serotonin reuptake inhibitors. Pexep CR 12.5 Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder. Pexep CR 12.5 Tablet works by inhibiting serotonin's reuptake by nerves, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders. Pexep CR 12.5 Tablet has fewer unwanted side effects than older antidepressants and helps people recover from depression.

Directions for Use

Take Pexep CR 12.5 Tablet in the morning with food to prevent stomach upset. Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pexep CR 12.5 Tablet

  • Insomnia (difficulty sleeping)
  • Headache
  • Diarrhoea
  • Nausea
  • Fatigue
  • Dry mouth
  • Loss of appetite
  • Sexual disturbances

Drug Warnings

Do not take Pexep CR 12.5 Tablet if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MAOI) or have taken them in the last 14 days, or if you are taking antipsychotic medicines such as thioridazine or pimozide. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Inform your doctor if you have/had epilepsy, mania, diabetes, low sodium levels in blood, glaucoma, or are undergoing treatment for severe depression called electro-convulsive therapy. Do not take Pexep CR 12.5 Tablet if you are pregnant, as it may cause harm to the foetus. Consult your doctor before taking Pexep CR 12.5 Tablet if you are breastfeeding. Avoid driving or operating machinery as Pexep CR 12.5 Tablet may cause dizziness, confusion, sleepiness and blurred vision. Pexep CR 12.5 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Avoid consumption of alcohol while taking Pexep CR 12.5 Tablet as it may make your symptoms or side-effects worse.

Drug Interactions

Drug-Drug Interactions: Pexep CR 12.5 Tablet may interact with blood thinners (warfarin, clopidogrel), anti-psychotics (perphenazine, thioridazine, clozapine. Lithium, risperidone), antidepressants (clomipramine, moclobemide, methylthioninium chloride/methylene blue, nortriptyline, desipramine), NSAID’s (acetylsalicylic acid, ibuprofen, celecoxib, etodolac, diclofenac, meloxicam, tramadol, pethidine), anti-cancer (tamoxifen), anti-migraine (sumatriptan), dietary supplement (tryptophan), opioid analgesics (fentanyl), anti-HIV (ritonavir, fosamprenavir), anti-convulsant (phenobarbital, phenytoin, carbamazepine), anti-arrhythmic (propafenone, flecainide), anti-hypertensive (metoprolol), anti-TB (rifampicin), antibiotic (linezolid), statin (pravastatin), neuromuscular blocker (mivacurium, suxamethonium), norepinephrine reuptake inhibitor (Atomoxetine), herbal supplement used to treat depression (St. John’s wort), and anticholinergic medication (Procyclidine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have glaucoma, diabetes, epilepsy, mania, bleeding problems, hyponatremia (low sodium levels), heart, liver or kidney dysfunction.

Drug-Drug Interactions Checker List

  • WARFARIN
  • CLOPIDOGREL
  • PERPHENAZINE
  • THIORIDAZINE
  • CLOZAPINE
  • LITHIUM
  • RISPERIDONE
  • CLOMIPRAMINE
  • MOCLOBEMIDE
  • METHYLENE BLUE
  • NORTRIPTYLINE
  • DESIPRAMINE
  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • ETODOLAC
  • DICLOFENAC
  • MELOXICAM
  • TRAMADOL
  • PETHIDINE
  • TAMOXIFEN
  • SUMATRIPTAN
  • FENTANYL
  • RITONAVIR
  • PHENOBARBITAL
  • PHENYTOIN
  • CARBAMAZEPINE
  • PROPAFENONE
  • FLECAINIDE
  • METOPROLOL
  • RIFAMPICIN
  • LINEZOLID
  • PRAVASTATIN
  • MIVACURIUM
  • ATOMOXETINE
  • PROCYCLIDINE
  • TRYPTOPHAN
  • FOSAMPRENAVIR
  • SUXAMETHONIUM

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosting self-esteem, and providing restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Special Advise

  • Close monitoring of patients taking Pexep CR 12.5 Tablet for suicidal behaviour is advised. Talk to your doctor immediately if you have thoughts of harming or killing yourself.

Disease/Condition Glossary

Major depressive disorder: Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. It mainly impacts mood, behaviour, and other physical functions, such as sleep and appetite. Symptoms include sadness, loss of interest, appetite changes, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty in concentrating, making decisions, and thinking. The exact cause of depression is unknown. However, factors such as stress, changes in hormone levels, alcohol or drug abuse, abuse during childhood, certain medical conditions and medications might increase the risk of developing depression. 

Obsessive-Compulsive Disorder (OCD): It is a mental disorder that is associated with repetitive thoughts (obsessions) and the urge to do things over and again (compulsions). Symptoms include fear of germs or the need to arrange objects in a specific manner.

Panic disorder: It is a type of anxiety disorder that causes panic attacks. In this condition, a person experiences a sudden feeling of fear, when, in reality, there is no danger. Symptoms include fast heartbeat, breathing difficulty, chest or stomach pain, weakness or dizziness, and sweating.

Social anxiety disorder: It is a chronic mental health condition that causes extreme fear, anxiety, embarrassment, and self-consciousness in social gatherings. Symptoms include excessive fear, worry about humiliation or embarrassment, concern about offending someone, and fear about being judged. 

Post-traumatic stress disorder (PTSD): It is a disorder that is characterised by failure to recover after witnessing or experiencing a terrifying event. This condition may last for a few months or years with triggers that could bring back the memories of trauma accompanied by intense physical and emotional reactions. Symptoms include nightmares, flashbacks, anxiety or depressed mood, heightened reactivity to a stimulus, and avoidance of situations that can bring back trauma. 

Generalised anxiety disorder: It is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety is the body’s natural response to stress, in which the feeling of fear may be intense and debilitating. It is the most common form of emotional disorder and can affect anyone at any age. Symptoms of anxiety include rapid breathing, increased heart rate, restlessness, trouble concentrating, and difficulty falling asleep.

Premenstrual dysphoric disorder: It is a severe form of premenstrual syndrome, which includes physical and behavioural symptoms that usually resolve after the period's onset. Premenstrual dysphoric disorder causes extreme mood shifts that can disrupt work and relationships. Symptoms include irritability, anger, hopelessness, sadness, bloating, and breast tenderness.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pexep CR 12.5 Tablet as it may make your symptoms or side-effects worse.

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Pregnancy

Unsafe

Pexep CR 12.5 Tablet belongs to pregnancy category D. It is not recommended to take Pexep CR 12.5 Tablet if you are pregnant or planning for pregnancy as Pexep CR 12.5 Tablet might cause foetal harm.

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Breast Feeding

Caution

Pexep CR 12.5 Tablet may pass into breastmilk. Consult your doctor before taking Pexep CR 12.5 Tablet ; your doctor will decide whether Pexep CR 12.5 Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Avoid driving or operating machinery as Pexep CR 12.5 Tablet may cause dizziness, confusion, sleepiness and blurred vision.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pexep CR 12.5 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - PEX0056

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Pexep CR 12.5 Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.
Pexep CR 12.5 Tablet works by inhibiting serotonin's reuptake by nerves, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This increases serotonin concentrations in the nerve synapse, thereby helping in regulating mood.
Do not discontinue Pexep CR 12.5 Tablet without consulting your doctor as it could lead to withdrawal effects. To treat your condition effectually, continue taking Pexep CR 12.5 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pexep CR 12.5 Tablet ; the doctor may reduce the dose gradually.
Pexep CR 12.5 Tablet may cause decreased libido (sex drive), impotence (erectile dysfunction), abnormal ejaculation and problems with orgasm. Consult your doctor if you have any concerns regarding this.
Dry mouth could be a side-effect of Pexep CR 12.5 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Please consult your doctor before taking Pexep CR 12.5 Tablet if you have glaucoma as Pexep CR 12.5 Tablet might cause increased pressure in the eye.
Consult your doctor before taking Pexep CR 12.5 Tablet if you have diabetes as Pexep CR 12.5 Tablet might fluctuate blood glucose levels. Regular monitoring of blood sugar levels is advised if you are taking Pexep CR 12.5 Tablet . Talk to your doctor if your blood sugar levels are unstable.
People taking antidepressants such as Pexep CR 12.5 Tablet are more likely at risk of developing suicidal thoughts. Talk to your doctor immediately if you have thoughts of harming or killing yourself.
Consult your doctor before taking tamoxifen (used to treat cancer) along with Pexep CR 12.5 Tablet as Pexep CR 12.5 Tablet might make tamoxifen less effective.
Pexep CR 12.5 Tablet may cause unusual bleeding or bruising such as vomiting blood or passing blood in stools. Therefore, talk to your doctor before taking Pexep CR 12.5 Tablet if you have a history of bleeding disorders or if you are taking medicines that might increase the risk of bleeding such as blood thinners (warfarin), anti-psychotics (perphenazine or clozapine), tricyclic antidepressants (clomipramine), or NSAID’s (acetylsalicylic acid, ibuprofen, celecoxib, etodolac, diclofenac, meloxicam).
Pexep CR 12.5 Tablet may cause side effects such as nausea, headache, diarrhoea, dry mouth, fatigue (overtiredness), loss of appetite and insomnia (difficulty sleeping). If these side effects persist or worsen, please consult your doctor.
Yes, bone fractures have been associated with Pexep CR 12.5 Tablet .
The risk of serotonin syndrome is increased when Pexep CR 12.5 Tablet is taken together with other serotonergic medicines, including tricyclic antidepressants, fentanyl, triptans, tramadol, buspirone, lithium, tryptophan, thioridazine, isocarboxazid, pimozide, intravenous methylene blue, linezolid, amphetamines, procarbazine, phenelzine, selegiline, tranylcypromine and St. John’s Wort.
You may start noticing an improvement in your symptoms after 1-2 weeks of starting the treatment with Pexep CR 12.5 Tablet . If you do not see any improvement, do not stop taking Pexep CR 12.5 Tablet and consult your doctor. It may take around 4-6 weeks to see the full effects of Pexep CR 12.5 Tablet .
No, do not stop taking Pexep CR 12.5 Tablet suddenly, without first consulting your doctor. This is a common problem with Pexep CR 12.5 Tablet that you may feel your symptoms have worsened initially but the benefits start showing after 1-2 weeks. You must consult your doctor if the worsening does not improve even after 1-2 weeks.
Pexep CR 12.5 Tablet is not recommended for children and adolescents below 18 years of age as patients in this age group have an increased risk of experiencing side effects such as aggression, suicidal thoughts, oppositional behavior and anger when they take Pexep CR 12.5 Tablet . If you have any concerns regarding this, please discuss with your doctor.
No, do not take Pexep CR 12.5 Tablet if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Pexep CR 12.5 Tablet . However, Pexep CR 12.5 Tablet may make tamoxifen less effective and can lead to recurrence of breast cancer.
Yes, you need to be careful while taking Pexep CR 12.5 Tablet if you are a diabetic as Pexep CR 12.5 Tablet may change your blood sugar levels. Thus, may need dose adjustment of your insulin or antidiabetic medicines. Discuss with your doctor regarding this and monitor your blood sugar levels regularly.
Pexep CR 12.5 Tablet is usually considered safe if taken as advised by a doctor. However, it may cause side effects, just like any medication. Discuss with your doctor about your concerns or potential risks before starting Pexep CR 12.5 Tablet .
No, Pexep CR 12.5 Tablet is not a sleeping pill. Although its calming effect can promote better sleep, its main purpose is to manage depression and anxiety symptoms.
Your doctor determines the best time to take Pexep CR 12.5 Tablet . It can be taken with or without food, but follow your doctor's instructions for dosage and timing.
It may take a few weeks for Pexep CR 12.5 Tablet to show improvements in your symptoms. Even if you do not see immediate results, it is important to keep taking it as prescribed by your doctor.
Yes, Pexep CR 12.5 Tablet helps manage various anxiety disorders such as obsessive-compulsive disorder and panic disorder. It helps reduce anxiety symptoms by restoring the balance of serotonin in the brain.
If you experience any side effects while taking Pexep CR 12.5 Tablet , inform your doctor immediately. After analysing your symptoms, they will modify your treatment plan.

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