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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Perinorm Injection 2 ml is an anti-emetic medication used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and post-operative conditions. It contains metoclopramide which increases the motility of the upper gastrointestinal tract and thus helps in gastric emptying. Some of the common side effects include fatigue, dizziness, headache, and bowel disturbances.
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Composition :

METOCLOPRAMIDE-5MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Perinorm Injection 2 ml

Perinorm Injection 2 ml belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Perinorm Injection 2 ml is also used to treat delayed gastric emptying. Perinorm Injection 2 ml may be used to facilitate small bowel intubation and to stimulate gastric emptying and intestinal transit of barium.

Perinorm Injection 2 ml contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

In some cases, Perinorm Injection 2 ml may cause common side-effects such as drowsiness, fatigue, dizziness, headache, and bowel disturbances. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Perinorm Injection 2 ml may cause drowsiness and dizziness affecting your ability to drive and operate machinery. Perinorm Injection 2 ml is not recommended for children below one year. Avoid consuming alcohol while on treatment with Perinorm Injection 2 ml as it could lead to increased drowsiness. Treatment with Perinorm Injection 2 ml is not recommended for longer than 12 weeks, except in rare cases.

Uses of Perinorm Injection 2 ml

Treatment of Nausea, vomiting and delayed gastric emptying

Directions for Use

Perinorm Injection 2 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Perinorm Injection 2 ml belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Perinorm Injection 2 ml is also used to treat delayed gastric emptying. Perinorm Injection 2 ml may be used to facilitate small bowel intubation and to facilitate gastric emptying and intestinal transit of barium in patients where delayed emptying interrupts radiological examination of the stomach and/or small intestine. Perinorm Injection 2 ml contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

How Perinorm Injection 2 ml Works

Perinorm Injection 2 ml contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Perinorm Injection 2 ml

  • Drowsiness
  • Fatigue
  • Dizziness
  • Headache
  • Bowel disturbances

What if I have taken an overdose of Perinorm Injection 2 ml

Perinorm Injection 2 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include drowsiness, disorientation and extrapyramidal reactions. Your doctor may take immediate necessary measures if an overdose is suspected.

Drug Warnings

Do not take Perinorm Injection 2 ml if you are allergic to any of its components; if you have gastrointestinal bleeding, mechanical obstruction/perforation, pheochromocytoma (tumour in the adrenal glands), or epilepsy. Perinorm Injection 2 ml may cause neuroleptic malignant syndrome (a nervous disorder with high fever and muscle stiffness), extrapyramidal symptoms (shaking, tremor, stiffness and involuntary movement), Tardive dyskinesia (movement disorder), Parkinson-like symptoms (bradykinesia, tremor, cogwheel rigidity, or mask-like facies), and depression. Inform your doctor if you have heart problems, diabetes, depression, high blood pressure, breast cancer, seizures, Parkinson’s disease, methaemoglobinaemia, or liver or kidney problems. Consult your doctor immediately if you cannot stop or control movements like shaking your arms and legs, blinking and moving your eyes, sticking out the tongue, frowning, lip-smacking, chewing, or puckering up the mouth.

Drug-Drug Interactions

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MetoclopramideRisperidone
Critical
MetoclopramideAmisulpride
Critical

Drug-Drug Interactions

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MetoclopramideRisperidone
Critical
How does the drug interact with Perinorm Injection 2 ml:
Co-administration of Perinorm Injection 2 ml with Risperidone can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Risperidone with Perinorm Injection 2 ml is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking, jitteriness, restlessness, pacing, and foot tapping contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
MetoclopramideAmisulpride
Critical
How does the drug interact with Perinorm Injection 2 ml:
Taking Perinorm Injection 2 ml with Amisulpride may increase the risk or severity of side effects.

How to manage the interaction:
Taking Amisulpride with Perinorm Injection 2 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
MetoclopramideClozapine
Critical
How does the drug interact with Perinorm Injection 2 ml:
Co-administration of Perinorm Injection 2 ml with Clozapine can increase the risk of side effects.

How to manage the interaction:
Taking Perinorm Injection 2 ml with Clozapine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideBupropion
Critical
How does the drug interact with Perinorm Injection 2 ml:
Co-administration of Perinorm Injection 2 ml with Bupropion can increase the levels of Perinorm Injection 2 ml and increase the risk or severity of developing seizures (fits).

How to manage the interaction:
Taking Perinorm Injection 2 ml with Bupropion is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideAmoxapine
Critical
How does the drug interact with Perinorm Injection 2 ml:
Co-administration of Perinorm Injection 2 ml with Amoxapine can increase the risk of side effects.

How to manage the interaction:
Taking Perinorm Injection 2 ml with Amoxapine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideZiprasidone
Critical
How does the drug interact with Perinorm Injection 2 ml:
Taking Perinorm Injection 2 ml with Ziprasidone can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Perinorm Injection 2 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience lip-smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not discontinue any medications without consulting a doctor.
MetoclopramideVenlafaxine
Critical
How does the drug interact with Perinorm Injection 2 ml:
Coadministration of Perinorm Injection 2 ml with Venlafaxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Perinorm Injection 2 ml with Venlafaxine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideMethyldopa
Critical
How does the drug interact with Perinorm Injection 2 ml:
Taking Methyldopa and Perinorm Injection 2 ml together can decrease the levels and effects of Methyldopa.

How to manage the interaction:
Taking Perinorm Injection 2 ml with Methyldopa is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramidePromethazine
Critical
How does the drug interact with Perinorm Injection 2 ml:
Coadministration of Perinorm Injection 2 ml with Promethazine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Promethazine with Perinorm Injection 2 ml is generally avoided as it can possibly result in an interaction. They can be taken together However, consult a doctor if you experience puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.
MetoclopramideCitalopram
Critical
How does the drug interact with Perinorm Injection 2 ml:
Coadministration of Citalopram with Perinorm Injection 2 ml can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Citalopram with Perinorm Injection 2 ml is generally avoided as it can possibly result in an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Drink fluids to stay hydrated.
  • Avoid solid foods until vomiting stops.
  • Avoid foods that might cause stomach upset.
  • Take ample rest. Avoid any activity immediately after eating.
  • Consume plain, light foods such as bread and biscuits.
  • Avoid food with strong flavours and fried food.
  • Ginger tea might help in proper digestion.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Perinorm Injection 2 ml Substitute

Substitutes safety advice
  • Perinorm Syrup 60 ml

    by AYUR

    0.50per tablet
  • Perinorm Injection 10ml

    3.29per tablet
  • EMENORM INJECTION

    4.95per tablet
  • Perinorm Injection 20 ml

    by AYUR

    1.62per tablet
  • Vominil Syrup 30 ml

    1.13per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while on treatment with Perinorm Injection 2 ml as it may cause increased sleepiness and drowsiness.

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Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Perinorm Injection 2 ml may be excreted in human milk. Consult your doctor if you are breastfeeding.

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Driving

Caution

Perinorm Injection 2 ml may cause dizziness and drowsiness. Do not drive or operate machinery until you know how Perinorm Injection 2 ml affects you.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Perinorm Injection 2 ml is not recommended for children below one year.

FAQs

Perinorm Injection 2 ml belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Perinorm Injection 2 ml is also used to treat delayed gastric emptying.
Perinorm Injection 2 ml works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.
Perinorm Injection 2 ml may cause tardive dyskinesia (movement disorder) that is often irreversible. The risk increases with the duration of treatment and dosage. Perinorm Injection 2 ml therapy should be discontinued in patients who develop the symptoms of tardive dyskinesia. Consult your doctor immediately if you notice symptoms such as involuntary movements of the face, tongue, mouth, jaw, trunk and/or extremities.
Perinorm Injection 2 ml may be used to facilitate small bowel intubation (the process of passing a small, flexible plastic tube through the nose/mouth into the stomach/small intestine) in adults and pediatric patients in whom the tube does not pass the pylorus (the opening from the stomach into the duodenum) with conventional manoeuvres.
Treatment with Perinorm Injection 2 ml should be avoided for longer than 12 weeks except in rare cases where benefits outweigh the risks of developing tardive dyskinesia.
Perinorm Injection 2 ml may cause depression in people with or without a medical history of depression. Consult your doctor immediately if you have any suicidal thoughts, such as killing or harming yourself.
Perinorm Injection 2 ml may be used to facilitate gastric emptying and intestinal transit of barium in patients where delayed emptying interrupts radiological examination of the stomach and/or small intestine.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - PER0018

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