Perinorm Injection belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Perinorm Injection is also used to treat delayed gastric emptying. Perinorm Injection may be used to facilitate small bowel intubation and to stimulate gastric emptying and intestinal transit of barium.

Perinorm Injection contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

In some cases, Perinorm Injection may cause common side-effects such as drowsiness, fatigue, dizziness, headache, and bowel disturbances. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Perinorm Injection may cause drowsiness and dizziness affecting your ability to drive and operate machinery. Perinorm Injection is not recommended for children below one year. Avoid consuming alcohol while on treatment with Perinorm Injection as it could lead to increased drowsiness. Treatment with Perinorm Injection is not recommended for longer than 12 weeks, except in rare cases.

Perinorm Injection belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Perinorm Injection is also used to treat delayed gastric emptying. Perinorm Injection may be used to facilitate small bowel intubation and to facilitate gastric emptying and intestinal transit of barium in patients where delayed emptying interrupts radiological examination of the stomach and/or small intestine. Perinorm Injection contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

• Drowsiness
• Fatigue
• Dizziness
• Headache
• Bowel disturbances

Do not take Perinorm Injection if you are allergic to any of its components; if you have gastrointestinal bleeding, mechanical obstruction/perforation, pheochromocytoma (tumour in the adrenal glands), or epilepsy. Perinorm Injection may cause neuroleptic malignant syndrome (a nervous disorder with high fever and muscle stiffness), extrapyramidal symptoms (shaking, tremor, stiffness and involuntary movement), Tardive dyskinesia (movement disorder), Parkinson-like symptoms (bradykinesia, tremor, cogwheel rigidity, or mask-like facies), and depression. Inform your doctor if you have heart problems, diabetes, depression, high blood pressure, breast cancer, seizures, Parkinson’s disease, methaemoglobinaemia, or liver or kidney problems. Consult your doctor immediately if you cannot stop or control movements like shaking your arms and legs, blinking and moving your eyes, sticking out the tongue, frowning, lip-smacking, chewing, or puckering up the mouth.

Drug-Drug Interactions: Perinorm Injection may interact with antiparkinson agent (levodopa), cardiac glycoside (digoxin), drugs used to treat depression (monoamine oxidase inhibitors), sedatives, hypnotics, anxiolytics, and narcotics.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interaction: Inform your doctor if you have gastrointestinal disorders, depression, seizures, high blood pressure, parkinsonism, pheochromocytoma (tumour of the adrenal gland), neuroleptic malignant syndrome (a nervous disorder with high fever and muscle stiffness), or tardive dyskinesia (jerky, stiff movements of the face).

• LEVODOPA
• DIGOXIN

• Eat smaller meals more often.
• Drink fluids to stay hydrated.
• Avoid solid foods until vomiting stops.
• Avoid foods that might cause stomach upset.
• Take ample rest. Avoid any activity immediately after eating.
• Consume plain, light foods such as bread and biscuits.
• Avoid food with strong flavours and fried food.
• Ginger tea might help in proper digestion.

Nausea/Vomiting: Nausea is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the contents of the stomach through the mouth. Nausea and vomiting may occur separately or together. The common causes include motion sickness, emotional stress, indigestion, food poisoning, high fever or overeating. Nausea/vomiting might also occur as an unpleasant effect of therapy, such as chemotherapy and radiation therapy. 

Gastroparesis: Gastroparesis or delayed gastric emptying is a condition that occurs when the stomach takes too long to empty the food into the intestine. Symptoms include nausea, vomiting, indigestion, loss of appetite, bloating and heartburn.