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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Perihart 4 mg Tablet is prescribed alone or in combination with other drugs used to treat high blood pressure and heart failure. It contains Perindopril, which relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. In addition to this, it also reduces the physical effects of anxiety. It may cause side effects such as headaches, ankle swelling, slow heart rate, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

PERINDOPRIL-4MG

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Perihart 4 mg Tablet

Perihart 4 mg Tablet is anti-hypertensive medication, prescribed alone or in combination with other drugs. Perihart 4 mg Tablet belongs to angiotensin-converting enzyme (ACE) inhibitors, primarily used to treat high blood pressure and heart failure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Perihart 4 mg Tablet contains Perindopril, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perihart 4 mg Tablet relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. However, Perihart 4 mg Tablet does not cure high blood pressure (hypertension) but does help control it. In addition to this, Perihart 4 mg Tablet also reduces the physical effects of anxiety.

You can take Perihart 4 mg Tablet with a meal or after/before a meal. Your doctor will advise you on the exact dosage and how often you have to take Perihart 4 mg Tablet based on your medical condition. You may sometimes experience headaches, ankle swelling, slow heart rate, and nausea. Perihart 4 mg Tablet may lower your blood pressure, especially if taken with alcohol. So, avoid driving and operating heavy machinery. Most of these side effects of Perihart 4 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own, even if your blood pressure becomes routine. Tell your doctor if you have had or currently have liver, kidney, or heart problems. Inform your doctor if you are allergic or hypersensitive to any component present in Perihart 4 mg Tablet or if you are pregnant, suspect you are pregnant, plan to have a baby or if you are breastfeeding; your doctor will prescribe Perihart 4 mg Tablet only if the benefits outweigh the risk. Before taking the Perihart 4 mg Tablet , inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Uses of Perihart 4 mg Tablet

Treatment of Hypertension, Prevention of heart attack.

Directions for Use

Swallow Perihart 4 mg Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Perihart 4 mg Tablet contains Perindopril, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perihart 4 mg Tablet allows these constricted blood vessels to relax and, therefore, help lower high blood pressure. However, Perihart 4 mg Tablet does not cure high blood pressure (hypertension) but does help control it. In addition to this, Perihart 4 mg Tablet also reduces the physical effects of anxiety.

How Perihart 4 mg Tablet Works

Perihart 4 mg Tablet contains Perindopril, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perihart 4 mg Tablet relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. However, Perihart 4 mg Tablet does not cure high blood pressure (hypertension) but does help control it. In addition to this, Perihart 4 mg Tablet also reduces the physical effects of anxiety.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Perihart 4 mg Tablet

  • Cough

  • Feeling dizzy or lightheaded

  • Headaches

  • Blurred vision

  • Weakness

  • Nausea (feeling sick)

What if I have taken an overdose of Perihart 4 mg Tablet

Do not take more than the prescribed dose of Perihart 4 mg Tablet as it may cause overdose. The symptoms of overdose include sleepiness, papitations (pounding heartbeat) and dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Perihart 4 mg Tablet should not be given to the people allergic to Perihart 4 mg Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Besides this, tell your doctor if you have low blood pressure (hypotension), heart disease, liver disease, kidney disease, or are currently on dialysis. Perihart 4 mg Tablet is not recommended in neonates and children with worse kidney functioning (glomerular filtration rate <30 mL/min). The raised bilirubin level has been reported in some cases, so patients with liver diseases (like cirrhosis, jaundice, yellowing of skin/eye, etc.) should take the Perihart 4 mg Tablet with caution. Do not take Perihart 4 mg Tablet with alcohol as it may cause low blood pressure (hypotension) with symptoms of dizziness, drowsiness, weariness, or sleepiness. Tell your doctor you are using the Perihart 4 mg Tablet before undergoing dental or other surgery. Your doctor might stop this medicine before the surgery.

Drug-Drug Interactions

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PerindoprilAliskiren
Critical
PerindoprilSpironolactone
Severe

Drug-Drug Interactions

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PerindoprilAliskiren
Critical
How does the drug interact with Perihart 4 mg Tablet 10's:
Combining Aliskiren with Perihart 4 mg Tablet 10's can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Perihart 4 mg Tablet 10's with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PerindoprilSpironolactone
Severe
How does the drug interact with Perihart 4 mg Tablet 10's:
Using Perihart 4 mg Tablet 10's together with spironolactone may cause hyperkalemia (high potassium level in blood).

How to manage the interaction:
Although taking spironolactone and Perihart 4 mg Tablet 10's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop using any medications without consulting doctor.
PerindoprilTrimethoprim
Severe
How does the drug interact with Perihart 4 mg Tablet 10's:
Taking Perihart 4 mg Tablet 10's with trimethoprim can cause hyperkalemia(high levels of potassium in blood) which can increase the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Co-administration of Perihart 4 mg Tablet 10's with Trimethoprim can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without consulting your doctor.
PerindoprilLithium
Severe
How does the drug interact with Perihart 4 mg Tablet 10's:
Perihart 4 mg Tablet 10's when taken together with lithium may significantly increase the blood levels of lithium.

How to manage the interaction:
Although there is drug interaction between Perihart 4 mg Tablet 10's and lithium, but can be taken together if advised by a doctor. if experience dizziness, confusion, diarrhea, vomiting, muscle weakness, tremor (shaking of hand & legs) blurred vision, ringing in the ear, excessive thirst, and/or increased urination consult a doctor immediately. Do not discontinue medications without consulting a doctor.
PerindoprilAmiloride
Severe
How does the drug interact with Perihart 4 mg Tablet 10's:
Amiloride when taken with Perihart 4 mg Tablet 10's may cause a hyperkalemia (high potassium levels in blood).

How to manage the interaction:
Although taking amiloride and Perihart 4 mg Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience symptoms including fatigue, disorientation, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
PerindoprilValsartan
Severe
How does the drug interact with Perihart 4 mg Tablet 10's:
Coadministration of Perihart 4 mg Tablet 10's with Valsartan may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Perihart 4 mg Tablet 10's together with Valsartan may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience symptoms such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
PerindoprilLeflunomide
Severe
How does the drug interact with Perihart 4 mg Tablet 10's:
Using leflunomide together with Perihart 4 mg Tablet 10's can increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Leflunomide and Perihart 4 mg Tablet 10's, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, liver damage or bleeding - make sure to contact your doctor right away. Do not stop using any medications without talking to your doctor.
PerindoprilPotassium gluconate
Severe
How does the drug interact with Perihart 4 mg Tablet 10's:
Combining Potassium gluconate with Perihart 4 mg Tablet 10's can cause hyperkalemia(high levels of potassium in blood) which increase the risk of kidney problems and abnormal heart rhythm..

How to manage the interaction:
Taking Perihart 4 mg Tablet 10's with Potassium gluconate together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without first consulting your doctor.
PerindoprilPiroxicam
Severe
How does the drug interact with Perihart 4 mg Tablet 10's:
Using Perihart 4 mg Tablet 10's together with piroxicam may reduce the effects of Perihart 4 mg Tablet 10's in lowering blood pressure, they may also increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Piroxicam with Perihart 4 mg Tablet 10's can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, and irregular heart rhythm, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
PerindoprilTeriflunomide
Severe
How does the drug interact with Perihart 4 mg Tablet 10's:
Using Teriflunomide together with Perihart 4 mg Tablet 10's can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Perihart 4 mg Tablet 10's and Teriflunomide, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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PERINDOPRIL-4MGPotassium rich foods
Moderate

Drug-Food Interactions

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PERINDOPRIL-4MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Perihart 4 mg Tablet 10's with potassium-containing foods can increase the risk of hyperkalemia (high potassium levels in the blood). Avoid moderately high or high potassium dietary intake with Perihart 4 mg Tablet 10's, as it can lead to an interaction.

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg daily or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two for men is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Try to include heart-healthy omega-3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to help lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Perihart 4 mg Tablet Substitute

Substitutes safety advice
  • Perigard 4 mg Tablet 10's

    12.06per tablet
  • Coveril 4 Tablet 10's

    14.70per tablet
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Alcohol

Unsafe

Perihart 4 mg Tablet may enhance the hypotensive (low blood pressure) effect of this drug. For better advice, you should consult your doctor whether you can take Perihart 4 mg Tablet with alcohol.

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Pregnancy

Unsafe

The use of Perihart 4 mg Tablet or any ACE inhibitors is usually contraindicated during the second and third trimesters of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using Perihart 4 mg Tablet .

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Breast Feeding

Caution

Use of Perihart 4 mg Tablet is not recommended during the breastfeeding stage.

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Driving

Unsafe

Drive with caution, Perihart 4 mg Tablet may cause blurry vision, and dizziness or weariness may occur.

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Liver

Caution

Rare elevation in the liver enzymes (like bilirubin) has been observed while taking Perihart 4 mg Tablet , so it must be taken with caution. If you have a history of liver diseases/conditions, the dose may have to be adjusted by your doctor.

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Kidney

Caution

Perihart 4 mg Tablet to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. Perihart 4 mg Tablet should be given with precaution in hemodialysis condition.

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Children

Caution

Perihart 4 mg Tablet is not recommended for children. The safety and effectiveness of Perihart 4 mg Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Perihart 4 mg Tablet or not.

FAQs

Perihart 4 mg Tablet is used to treat high blood pressure and heart failure.
Perihart 4 mg Tablet contains Perindopril, and it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perihart 4 mg Tablet relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. However, Perihart 4 mg Tablet does not cure high blood pressure (hypertension) but does help control it.
No, alcohol should be avoided while taking Perihart 4 mg Tablet as it may cause excessive drowsiness. It enhances the hypotensive (low blood pressure) effect of Perihart 4 mg Tablet . For better advice, you should consult your doctor whether you can take Perihart 4 mg Tablet with alcohol.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.
The use of Perihart 4 mg Tablet is not recommended during the first trimester of pregnancy. The use of Perihart 4 mg Tablet or any ACE inhibitors is usually contraindicated during the second and third trimester of pregnancy. Hence, you should always consult your doctor's doctor before using Perihart 4 mg Tablet .
It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shot up at any time. If you have any discomfort, please consult your doctor immediately.
Usually, Perihart 4 mg Tablet is prescribed for a long term treatment ranging from months to years for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.
Before surgery, you should inform your doctor that you are taking Perihart 4 mg Tablet to reduce your blood pressure when used along with anesthesia, which is given before a major operation.
If you forget to take Perihart 4 mg Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

Country of origin

India

Manufacturer/Marketer address

20, Dr. E. Moses Road, Mahalaxmi, Mumbai - 400 011
Other Info - PER0114

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