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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Perigard 4 mg Tablet is prescribed alone or in combination with other drugs used to treat high blood pressure and heart failure. It contains Perindopril, which relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. In addition to this, it also reduces the physical effects of anxiety. It may cause side effects such as headaches, ankle swelling, slow heart rate, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Whats That

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Composition :

PERINDOPRIL-4MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Perigard 4 mg Tablet

Perigard 4 mg Tablet is anti-hypertensive medication, prescribed alone or in combination with other drugs. Perigard 4 mg Tablet belongs to angiotensin-converting enzyme (ACE) inhibitors, primarily used to treat high blood pressure and heart failure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Perigard 4 mg Tablet contains Perindopril, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perigard 4 mg Tablet relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. However, Perigard 4 mg Tablet does not cure high blood pressure (hypertension) but does help control it. In addition to this, Perigard 4 mg Tablet also reduces the physical effects of anxiety.

You can take Perigard 4 mg Tablet with a meal or after/before a meal. Your doctor will advise you on the exact dosage and how often you have to take Perigard 4 mg Tablet based on your medical condition. You may sometimes experience headaches, ankle swelling, slow heart rate, and nausea. Perigard 4 mg Tablet may lower your blood pressure, especially if taken with alcohol. So, avoid driving and operating heavy machinery. Most of these side effects of Perigard 4 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own, even if your blood pressure becomes routine. Tell your doctor if you have had or currently have liver, kidney, or heart problems. Inform your doctor if you are allergic or hypersensitive to any component present in Perigard 4 mg Tablet or if you are pregnant, suspect you are pregnant, plan to have a baby or if you are breastfeeding; your doctor will prescribe Perigard 4 mg Tablet only if the benefits outweigh the risk. Before taking the Perigard 4 mg Tablet , inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Uses of Perigard 4 mg Tablet

Treatment of Hypertension, Prevention of heart attack.

Directions for Use

Swallow Perigard 4 mg Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Perigard 4 mg Tablet contains Perindopril, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perigard 4 mg Tablet allows these constricted blood vessels to relax and, therefore, help lower high blood pressure. However, Perigard 4 mg Tablet does not cure high blood pressure (hypertension) but does help control it. In addition to this, Perigard 4 mg Tablet also reduces the physical effects of anxiety.

How Perigard 4 mg Tablet Works

Perigard 4 mg Tablet contains Perindopril, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perigard 4 mg Tablet relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. However, Perigard 4 mg Tablet does not cure high blood pressure (hypertension) but does help control it. In addition to this, Perigard 4 mg Tablet also reduces the physical effects of anxiety.

Storage

Store in a cool and dry place away from sunlight
Side effects of Perigard 4 mg Tablet
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Perigard 4 mg Tablet

Do not take more than the prescribed dose of Perigard 4 mg Tablet as it may cause overdose. The symptoms of overdose include sleepiness, papitations (pounding heartbeat) and dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Perigard 4 mg Tablet should not be given to the people allergic to Perigard 4 mg Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Besides this, tell your doctor if you have low blood pressure (hypotension), heart disease, liver disease, kidney disease, or are currently on dialysis. Perigard 4 mg Tablet is not recommended in neonates and children with worse kidney functioning (glomerular filtration rate <30 mL/min). The raised bilirubin level has been reported in some cases, so patients with liver diseases (like cirrhosis, jaundice, yellowing of skin/eye, etc.) should take the Perigard 4 mg Tablet with caution. Do not take Perigard 4 mg Tablet with alcohol as it may cause low blood pressure (hypotension) with symptoms of dizziness, drowsiness, weariness, or sleepiness. Tell your doctor you are using the Perigard 4 mg Tablet before undergoing dental or other surgery. Your doctor might stop this medicine before the surgery.

Drug-Drug Interactions

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PerindoprilPotassium acetate
Severe

Drug-Drug Interactions

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How does the drug interact with Perigard 4 mg Tablet:
Combining Aliskiren with Perigard 4 mg Tablet can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Perigard 4 mg Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PerindoprilPotassium acetate
Severe
How does the drug interact with Perigard 4 mg Tablet:
Taking potassium acetate with Perigard 4 mg Tablet can increase the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Although taking Perigard 4 mg Tablet and Potassium acetate together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Perigard 4 mg Tablet:
Using Perigard 4 mg Tablet together with dalteparin may increase the risk of side effects of Perigard 4 mg Tablet.

How to manage the interaction:
Taking Perigard 4 mg Tablet with Dalteparin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Perigard 4 mg Tablet:
Coadministration of Perigard 4 mg Tablet with Valsartan may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Perigard 4 mg Tablet together with Valsartan may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience symptoms such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Perigard 4 mg Tablet:
Using Perigard 4 mg Tablet together with piroxicam may reduce the effects of Perigard 4 mg Tablet in lowering blood pressure, they may also increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Piroxicam with Perigard 4 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, and irregular heart rhythm, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Perigard 4 mg Tablet:
Taking Perigard 4 mg Tablet with trimethoprim can cause hyperkalemia(high levels of potassium in blood) which can increase the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Co-administration of Perigard 4 mg Tablet with Trimethoprim can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Perigard 4 mg Tablet:
Co-administration of Allopurinol with Perigard 4 mg Tablet may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Allopurinol and Perigard 4 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms, contact your doctor immediately . Do not discontinue any medications without consulting a doctor.
PerindoprilMipomersen
Severe
How does the drug interact with Perigard 4 mg Tablet:
Using Perigard 4 mg Tablet together with mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Perigard 4 mg Tablet with Mipomersen can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
PerindoprilTriamterene
Severe
How does the drug interact with Perigard 4 mg Tablet:
Combining Triamterene with Perigard 4 mg Tablet can increase the risk of hyperkalemia.

How to manage the interaction:
Although taking Perigard 4 mg Tablet and Triamterene together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Perigard 4 mg Tablet:
Combining Tizanidine with Perigard 4 mg Tablet can increase the risk of low blood pressure.

How to manage the interaction:
Co-administration of Tizanidine with Perigard 4 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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PERINDOPRIL-4MGPotassium rich foods
Moderate

Drug-Food Interactions

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PERINDOPRIL-4MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Perigard 4 mg Tablet with potassium-containing foods can increase the risk of hyperkalemia (high potassium levels in the blood). Avoid moderately high or high potassium dietary intake with Perigard 4 mg Tablet, as it can lead to an interaction.

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg daily or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two for men is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Try to include heart-healthy omega-3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to help lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Unsafe

Perigard 4 mg Tablet may enhance the hypotensive (low blood pressure) effect of this drug. For better advice, you should consult your doctor whether you can take Perigard 4 mg Tablet with alcohol.

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Pregnancy

Unsafe

The use of Perigard 4 mg Tablet or any ACE inhibitors is usually contraindicated during the second and third trimesters of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using Perigard 4 mg Tablet .

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Breast Feeding

Caution

Use of Perigard 4 mg Tablet is not recommended during the breastfeeding stage.

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Driving

Unsafe

Drive with caution, Perigard 4 mg Tablet may cause blurry vision, and dizziness or weariness may occur.

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Liver

Caution

Rare elevation in the liver enzymes (like bilirubin) has been observed while taking Perigard 4 mg Tablet , so it must be taken with caution. If you have a history of liver diseases/conditions, the dose may have to be adjusted by your doctor.

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Kidney

Caution

Perigard 4 mg Tablet to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. Perigard 4 mg Tablet should be given with precaution in hemodialysis condition.

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Children

Caution

Perigard 4 mg Tablet is not recommended for children. The safety and effectiveness of Perigard 4 mg Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Perigard 4 mg Tablet or not.

Have a query?

FAQs

Perigard 4 mg Tablet is used to treat high blood pressure and heart failure.

Perigard 4 mg Tablet contains Perindopril, and it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perigard 4 mg Tablet relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. However, Perigard 4 mg Tablet does not cure high blood pressure (hypertension) but does help control it.

No, alcohol should be avoided while taking Perigard 4 mg Tablet as it may cause excessive drowsiness. It enhances the hypotensive (low blood pressure) effect of Perigard 4 mg Tablet . For better advice, you should consult your doctor whether you can take Perigard 4 mg Tablet with alcohol.

No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.

The use of Perigard 4 mg Tablet is not recommended during the first trimester of pregnancy. The use of Perigard 4 mg Tablet or any ACE inhibitors is usually contraindicated during the second and third trimester of pregnancy. Hence, you should always consult your doctor&#039;s doctor before using Perigard 4 mg Tablet .

It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shot up at any time. If you have any discomfort, please consult your doctor immediately.

Usually, Perigard 4 mg Tablet is prescribed for a long term treatment ranging from months to years for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor&#039;s consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.

Before surgery, you should inform your doctor that you are taking Perigard 4 mg Tablet to reduce your blood pressure when used along with anesthesia, which is given before a major operation.

If you forget to take Perigard 4 mg Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai ? 400 026.
Other Info - PER0012

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