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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Pentanerv M 100 Tablet is used to treat neuropathic pain. It contains Gabapentin and Methylcobalamin which rejuvenate and protect damaged nerve cells. In some cases, this medicine may cause side effects such as dizziness, sleepiness, tiredness, nausea and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Pentanerv M 100 Tablet

Pentanerv M 100 Tablet belongs to a class of 'anticonvulsants,' primarily used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia. Epilepsy is a neurological condition in which the brain's activity becomes abnormal with seizure episodes, sometimes losing awareness or consciousness. Neuralgia is a chronic pain condition of the nerves that occurs due to nerve damage or other neurological conditions like neuropathy, trigeminal neuralgia or shingles.

Pentanerv M 100 Tablet consists of two drugs: Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin treats seizures or fits by balancing chemical messengers (neurotransmitters) in the brain, further reducing their abnormal excitement in the brain. Methylcobalamin is a coenzyme form of vitamin B12. It rejuvenates and protects damaged nerve cells by producing a substance called myelin. It also regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Pentanerv M 100 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Your doctor will decide the dosage and duration based on your medical condition. Sometimes, Pentanerv M 100 Tablet may have common side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

Let your doctor know if you are using any prescription, non-prescription drugs, and herbal products before starting Pentanerv M 100 Tablet . If you are a pregnant or breastfeeding mother, please consult your doctor before taking Pentanerv M 100 Tablet . Pentanerv M 100 Tablet causes drowsiness and dizziness, so drive only if you are alert. Pentanerv M 100 Tablet should not be given to children under three years old as safety and effectiveness have not been established. Avoid consuming alcohol along with Pentanerv M 100 Tablet as it could lead to increased dizziness and sleepiness. 

Uses of Pentanerv M 100 Tablet

Treatment of Neuropathic pain and Epilepsy (fits).

Directions for Use

Take Pentanerv M 100 Tablet with or without food. Swallow it as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Pentanerv M 100 Tablet is used to treat post-herpetic neuralgia and epilepsy. It contains Gabapentin (anti-convulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain and lowers the risk of seizures. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. It is also used to treat alcoholic neuropathy and diabetic neuropathy (nerve damage due to high blood sugar levels).

How Pentanerv M 100 Tablet Works

Pentanerv M 100 Tablet consists of two drugs: Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin treats seizures or fits by balancing chemical messengers (neurotransmitters) in the brain, further reducing their abnormal excitement in the brain. Methylcobalamin is a coenzyme form of vitamin B12. It rejuvenates and protects damaged nerve cells by producing a substance called myelin. It also regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Pentanerv M 100 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pentanerv M 100 Tablet

  • Dizziness

  • Sleepiness

  • Tiredness

  • Nausea 

  • Vomiting 

What if I have taken an overdose of Pentanerv M 100 Tablet

Take Pentanerv M 100 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor before taking Pentanerv M 100 Tablet if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Consult your doctor if you are on haemodialysis and experience muscle pain or weakness, persistent stomach pain, nausea, and vomiting. Please do not stop taking Pentanerv M 100 Tablet without consulting your doctor as it could cause withdrawal symptoms. Pregnant and breastfeeding women should consult their doctor before taking Pentanerv M 100 Tablet . Consult your doctor immediately if you experience suicidal tendencies. Keep Pentanerv M 100 Tablet away from direct sunlight. Do not store Pentanerv M 100 Tablet above 25ºC and keep it away from direct sunlight.

Drug-Drug Interactions

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GabapentinBuprenorphine
Severe
GabapentinPethidine
Severe

Drug-Drug Interactions

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GabapentinBuprenorphine
Severe
How does the drug interact with Pentanerv M 100 Tablet 10's:
Co-administration of Buprenorphine and Pentanerv M 100 Tablet 10's may cause central nervous system depression and lead to serious side effects (respiratory distress -build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Pentanerv M 100 Tablet 10's and Buprenorphine, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
GabapentinPethidine
Severe
How does the drug interact with Pentanerv M 100 Tablet 10's:
Combining Meperidine with Pentanerv M 100 Tablet 10's can increase the risk of CNS depression.

How to manage the interaction:
Co-administration of Pethidine with Pentanerv M 100 Tablet 10's can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
GabapentinSodium oxybate
Severe
How does the drug interact with Pentanerv M 100 Tablet 10's:
Taking Pentanerv M 100 Tablet 10's with Sodium oxybate can increase the side effects on the central nervous system.

How to manage the interaction:
Although taking Pentanerv M 100 Tablet 10's and Sodium oxybate together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - feeling tired, dizzy, lightheaded, confused, sad, having low blood pressure, or difficulty breathing - make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
GabapentinFentanyl
Severe
How does the drug interact with Pentanerv M 100 Tablet 10's:
Taking fentanyl with other drugs that cause central nervous system depression, such as Pentanerv M 100 Tablet 10's, might result in an increased risk of adverse effects.

How to manage the interaction:
Although combining Fentanyl and Pentanerv M 100 Tablet 10's may cause an interaction, they can be used if advised by your doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
GabapentinOxycodone
Severe
How does the drug interact with Pentanerv M 100 Tablet 10's:
Combining Oxycodone with Pentanerv M 100 Tablet 10's can increase the risk of CNS depression.

How to manage the interaction:
Taking Pentanerv M 100 Tablet 10's with Oxycodone together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GabapentinCodeine
Severe
How does the drug interact with Pentanerv M 100 Tablet 10's:
Combining Codeine with Pentanerv M 100 Tablet 10's can increase the risk of CNS depression.

How to manage the interaction:
Taking Pentanerv M 100 Tablet 10's with Codeine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, feeling dizzy or tired, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GabapentinSufentanil
Severe
How does the drug interact with Pentanerv M 100 Tablet 10's:
Combining Sufentanil with Pentanerv M 100 Tablet 10's can increase the risk of CNS depression.

How to manage the interaction:
There may be a possibility of interaction between Pentanerv M 100 Tablet 10's and Sufentanil, but it can be taken if prescribed by a doctor. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend different options that won't cause any problems. If you notice any symptoms like trouble breathing, feeling dizzy or tired, or having trouble focusing, make sure to call your doctor right away. Do not discontinue any medications without first consulting your doctor.
GabapentinHydrocodone
Severe
How does the drug interact with Pentanerv M 100 Tablet 10's:
When Hydrocodone is taken with Pentanerv M 100 Tablet 10's, the amount of Hydrocodone in the blood may be reduced.

How to manage the interaction:
Although there is a possible interaction between Pentanerv M 100 Tablet 10's and Hydrocodone, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GabapentinRemifentanil
Severe
How does the drug interact with Pentanerv M 100 Tablet 10's:
Combining Remifentanil with Pentanerv M 100 Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Pentanerv M 100 Tablet 10's with Remifentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
GabapentinKetamine
Severe
How does the drug interact with Pentanerv M 100 Tablet 10's:
Using Ketamine together with Pentanerv M 100 Tablet 10's may increase side effects.

How to manage the interaction:
Although taking Ketamine and Pentanerv M 100 Tablet 10's together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet as they can help in improving nerve health and preventing nerve pain.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well; get plenty of sleep.

  • Try taking a warm bath as it can be soothing. It helps in increasing blood circulation, thereby decreases numbness and pain.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Physical relaxation and massages can help provide symptomatic relief.

  • Learn about techniques for sitting, stretching, moving, and standing from a physical or occupational therapist. These can help prevent pain.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation and boosts healing.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Pentanerv M 100 Tablet Substitute

Substitutes safety advice
  • Gabaneuron 100 Tablet 15's

    by AYUR

    10.89per tablet
  • Gabapin ME 100 Tablet 15's

    11.76per tablet
  • Renerve-G 100 Capsule 10's

    11.52per tablet
  • Gabantin Plus Tablet 10's

    11.52per tablet
  • Doloneuron 100 Tablet 15's

    10.08per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pentanerv M 100 Tablet as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Pentanerv M 100 Tablet is not recommended during pregnancy unless prescribed by a doctor. Let your doctor know if you are pregnant or planning to conceive before taking Pentanerv M 100 Tablet .

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Breast Feeding

Caution

Gabapentin in Pentanerv M 100 Tablet is excreted into breast milk. Please consult your doctor before taking Pentanerv M 100 Tablet if you are breastfeeding.

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Driving

Unsafe

Pentanerv M 100 Tablet causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are mentally and physically alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Pentanerv M 100 Tablet . Dose adjustment may be needed in patients with liver impairment.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Pentanerv M 100 Tablet . Dose adjustment may be needed in patients with kidney impairment.

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Children

Caution

Pentanerv M 100 Tablet is not recommended in children less than three years of age. The doctor will prescribe the dosage of Pentanerv M 100 Tablet based on the child's age and weight.

FAQs

Pentanerv M 100 Tablet is used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia.
Pentanerv M 100 Tablet works by controlling the abnormal electrical activity of the brain that causes seizures (fits). It also helps in the rejuvenation and protection of damaged nerve cells.
Pentanerv M 100 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a balanced diet.
People taking Pentanerv M 100 Tablet should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.
If Pentanerv M 100 Tablet is taken along with antacid medicines containing aluminium and magnesium, it may lower the absorption of Pentanerv M 100 Tablet from the stomach. To avoid this, maintain a gap of two hours between Pentanerv M 100 Tablet and antacid medicines.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Neuropathic pain is a chronic progressive nerve disease that occurs due to damaged sensory nerves. Neuropathic pain is stabbing, tingling, and sharp while muscle pain is dull and steady or crampy and spasmodic.
Inform your doctor before taking Pentanerv M 100 Tablet if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Pregnant and breastfeeding women should consult their doctor before taking Pentanerv M 100 Tablet .
Pentanerv M 100 Tablet is a combination medicine containing Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). It is used to treat neuropathic pain.
Peripheral neuropathy affects the nerves outside your brain or spinal cord. It causes tingling sensation, pain, numbness and burning sensation.
Do not discontinue Pentanerv M 100 Tablet without consulting your doctor. To treat your condition effectively, keep taking Pentanerv M 100 Tablet for the prescribed duration.
Pentanerv M 100 Tablet may cause sleepiness as a side effect. Do not drive or operate machinery unless you are alert.
No, do not take a higher than the recommended dose of Pentanerv M 100 Tablet as it might cause an overdose. Take Pentanerv M 100 Tablet in the dose and duration prescribed by the doctor.
Store Pentanerv M 100 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Pentanerv M 100 Tablet may cause side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - PEN0489

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