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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Laregab-M 100/500 Tablet is used to treat neuropathic pain. It contains Gabapentin and Methylcobalamin which rejuvenate and protect damaged nerve cells. In some cases, this medicine may cause side effects such as dizziness, sleepiness, tiredness, nausea and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Laregab-M 100/500 Tablet

Laregab-M 100/500 Tablet belongs to a class of 'anticonvulsants,' primarily used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia. Epilepsy is a neurological condition in which the brain's activity becomes abnormal with seizure episodes, sometimes losing awareness or consciousness. Neuralgia is a chronic pain condition of the nerves that occurs due to nerve damage or other neurological conditions like neuropathy, trigeminal neuralgia or shingles.

Laregab-M 100/500 Tablet consists of two drugs: Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin treats seizures or fits by balancing chemical messengers (neurotransmitters) in the brain, further reducing their abnormal excitement in the brain. Methylcobalamin is a coenzyme form of vitamin B12. It rejuvenates and protects damaged nerve cells by producing a substance called myelin. It also regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Laregab-M 100/500 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Your doctor will decide the dosage and duration based on your medical condition. Sometimes, Laregab-M 100/500 Tablet may have common side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

Let your doctor know if you are using any prescription, non-prescription drugs, and herbal products before starting Laregab-M 100/500 Tablet . If you are a pregnant or breastfeeding mother, please consult your doctor before taking Laregab-M 100/500 Tablet . Laregab-M 100/500 Tablet causes drowsiness and dizziness, so drive only if you are alert. Laregab-M 100/500 Tablet should not be given to children under three years old as safety and effectiveness have not been established. Avoid consuming alcohol along with Laregab-M 100/500 Tablet as it could lead to increased dizziness and sleepiness. 

Uses of Laregab-M 100/500 Tablet

Treatment of Neuropathic pain and Epilepsy (fits).

Directions for Use

Take Laregab-M 100/500 Tablet with or without food. Swallow it as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Laregab-M 100/500 Tablet is used to treat post-herpetic neuralgia and epilepsy. It contains Gabapentin (anti-convulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain and lowers the risk of seizures. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. It is also used to treat alcoholic neuropathy and diabetic neuropathy (nerve damage due to high blood sugar levels).

How Laregab-M 100/500 Tablet Works

Laregab-M 100/500 Tablet consists of two drugs: Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin treats seizures or fits by balancing chemical messengers (neurotransmitters) in the brain, further reducing their abnormal excitement in the brain. Methylcobalamin is a coenzyme form of vitamin B12. It rejuvenates and protects damaged nerve cells by producing a substance called myelin. It also regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Laregab-M 100/500 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Laregab-M 100/500 Tablet

  • Dizziness

  • Sleepiness

  • Tiredness

  • Nausea 

  • Vomiting 

What if I have taken an overdose of Laregab-M 100/500 Tablet

Take Laregab-M 100/500 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor before taking Laregab-M 100/500 Tablet if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Consult your doctor if you are on haemodialysis and experience muscle pain or weakness, persistent stomach pain, nausea, and vomiting. Please do not stop taking Laregab-M 100/500 Tablet without consulting your doctor as it could cause withdrawal symptoms. Pregnant and breastfeeding women should consult their doctor before taking Laregab-M 100/500 Tablet . Consult your doctor immediately if you experience suicidal tendencies. Keep Laregab-M 100/500 Tablet away from direct sunlight. Do not store Laregab-M 100/500 Tablet above 25ºC and keep it away from direct sunlight.

Drug-Drug Interactions

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AmitriptylineSparfloxacin
Critical
AmitriptylineSaquinavir
Critical

Drug-Drug Interactions

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AmitriptylineSparfloxacin
Critical
How does the drug interact with Laregab-M 100 mg/500 mcg Tablet 10's:
Combining Laregab-M 100 mg/500 mcg Tablet 10's and Sparfloxacin may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Laregab-M 100 mg/500 mcg Tablet 10's with Sparfloxacin may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor. Note: Sparfloxacin is no longer available in the market. Grepafloxacin should not be combined with any other medications.
AmitriptylineSaquinavir
Critical
How does the drug interact with Laregab-M 100 mg/500 mcg Tablet 10's:
Combining Laregab-M 100 mg/500 mcg Tablet 10's and Saquinavir may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Laregab-M 100 mg/500 mcg Tablet 10's with Saquinavir may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineSafinamide
Critical
How does the drug interact with Laregab-M 100 mg/500 mcg Tablet 10's:
Using Laregab-M 100 mg/500 mcg Tablet 10's together with Safinamide can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Safinamide and Laregab-M 100 mg/500 mcg Tablet 10's together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Laregab-M 100 mg/500 mcg Tablet 10's. Do not discontinue any medications without consulting a doctor.
AmitriptylineDronedarone
Critical
How does the drug interact with Laregab-M 100 mg/500 mcg Tablet 10's:
Combining Laregab-M 100 mg/500 mcg Tablet 10's and Dronedarone may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Laregab-M 100 mg/500 mcg Tablet 10's with Dronedarone may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineTranylcypromine
Critical
How does the drug interact with Laregab-M 100 mg/500 mcg Tablet 10's:
Taking Tranylcypromine with Laregab-M 100 mg/500 mcg Tablet 10's can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although using Tranylcypromine and Laregab-M 100 mg/500 mcg Tablet 10's together is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
AmitriptylineFurazolidone
Critical
How does the drug interact with Laregab-M 100 mg/500 mcg Tablet 10's:
Combining Furazolidone with Laregab-M 100 mg/500 mcg Tablet 10's can increase the risk of serotonin syndrome(increased serotonin hormone).

How to manage the interaction:
Although using Furazolidone and Laregab-M 100 mg/500 mcg Tablet 10's together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Laregab-M 100 mg/500 mcg Tablet 10's. Do not discontinue any medications without consulting a doctor.
AmitriptylinePotassium chloride
Critical
How does the drug interact with Laregab-M 100 mg/500 mcg Tablet 10's:
The combination of Laregab-M 100 mg/500 mcg Tablet 10's and Potassium chloride may cause stomach and upper intestinal discomfort. (Only applicable to an oral preparation)

How to manage the interaction:
Although co-administration of Laregab-M 100 mg/500 mcg Tablet 10's and Potassium chloride is not recommended as it can possibly lead to an interaction, they can be taken if prescribed by a doctor. If you experience severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (in particular with blood), decreased hunger, and black stools while taking these medications, consult a doctor immediately. Do not discontinue any medications without talking to a doctor.
AmitriptylineHalofantrine
Critical
How does the drug interact with Laregab-M 100 mg/500 mcg Tablet 10's:
Combining Laregab-M 100 mg/500 mcg Tablet 10's and Halofantrine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Laregab-M 100 mg/500 mcg Tablet 10's with Halofantrine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineCisapride
Critical
How does the drug interact with Laregab-M 100 mg/500 mcg Tablet 10's:
Coadministration of Laregab-M 100 mg/500 mcg Tablet 10's and Cisapride may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Laregab-M 100 mg/500 mcg Tablet 10's with Cisapride may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineThioridazine
Critical
How does the drug interact with Laregab-M 100 mg/500 mcg Tablet 10's:
Laregab-M 100 mg/500 mcg Tablet 10's and Thioridazine can enhance each other's effects when used together.

How to manage the interaction:
Although using Laregab-M 100 mg/500 mcg Tablet 10's and Thioridazine together can cause an interaction, they can be used if prescribed by a doctor. If you have extreme sleepiness, confusion, anxiety, vomiting, vision problems, feeling hot or cold, sweating, muscle stiffness, fainting, fits, or coma, seek medical help. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet as they can help in improving nerve health and preventing nerve pain.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well; get plenty of sleep.

  • Try taking a warm bath as it can be soothing. It helps in increasing blood circulation, thereby decreases numbness and pain.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Physical relaxation and massages can help provide symptomatic relief.

  • Learn about techniques for sitting, stretching, moving, and standing from a physical or occupational therapist. These can help prevent pain.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation and boosts healing.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Laregab-M 100/500 Tablet Substitute

Substitutes safety advice
  • Gabapin ME 100 Tablet 15's

    11.76per tablet
  • Gabaneuron 100 Tablet 15's

    by AYUR

    10.89per tablet
  • Renerve-G 100 Capsule 10's

    11.52per tablet
  • Gabantin Plus Tablet 10's

    11.52per tablet
  • Doloneuron 100 Tablet 15's

    10.08per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Laregab-M 100/500 Tablet as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Laregab-M 100/500 Tablet is not recommended during pregnancy unless prescribed by a doctor. Let your doctor know if you are pregnant or planning to conceive before taking Laregab-M 100/500 Tablet .

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Breast Feeding

Caution

Gabapentin in Laregab-M 100/500 Tablet is excreted into breast milk. Please consult your doctor before taking Laregab-M 100/500 Tablet if you are breastfeeding.

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Driving

Unsafe

Laregab-M 100/500 Tablet causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are mentally and physically alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Laregab-M 100/500 Tablet . Dose adjustment may be needed in patients with liver impairment.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Laregab-M 100/500 Tablet . Dose adjustment may be needed in patients with kidney impairment.

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Children

Caution

Laregab-M 100/500 Tablet is not recommended in children less than three years of age. The doctor will prescribe the dosage of Laregab-M 100/500 Tablet based on the child's age and weight.

FAQs

Laregab-M 100/500 Tablet is used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia.
Laregab-M 100/500 Tablet works by controlling the abnormal electrical activity of the brain that causes seizures (fits). It also helps in the rejuvenation and protection of damaged nerve cells.
Laregab-M 100/500 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a balanced diet.
People taking Laregab-M 100/500 Tablet should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.
If Laregab-M 100/500 Tablet is taken along with antacid medicines containing aluminium and magnesium, it may lower the absorption of Laregab-M 100/500 Tablet from the stomach. To avoid this, maintain a gap of two hours between Laregab-M 100/500 Tablet and antacid medicines.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Neuropathic pain is a chronic progressive nerve disease that occurs due to damaged sensory nerves. Neuropathic pain is stabbing, tingling, and sharp while muscle pain is dull and steady or crampy and spasmodic.
Inform your doctor before taking Laregab-M 100/500 Tablet if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Pregnant and breastfeeding women should consult their doctor before taking Laregab-M 100/500 Tablet .
Laregab-M 100/500 Tablet is a combination medicine containing Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). It is used to treat neuropathic pain.
Peripheral neuropathy affects the nerves outside your brain or spinal cord. It causes tingling sensation, pain, numbness and burning sensation.
Do not discontinue Laregab-M 100/500 Tablet without consulting your doctor. To treat your condition effectively, keep taking Laregab-M 100/500 Tablet for the prescribed duration.
Laregab-M 100/500 Tablet may cause sleepiness as a side effect. Do not drive or operate machinery unless you are alert.
No, do not take a higher than the recommended dose of Laregab-M 100/500 Tablet as it might cause an overdose. Take Laregab-M 100/500 Tablet in the dose and duration prescribed by the doctor.
Store Laregab-M 100/500 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Laregab-M 100/500 Tablet may cause side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

Country of origin

India

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - LAR0245

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