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Parnil 5 mg Tablet 10's

Parnil 5 mg Tablet 10's

Prescription drug
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Consult Doctor

Manufacturer/Marketer

D D Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Parnil 5 mg Tablet

Parnil 5 mg Tablet is used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Parkinson’s disease is a progressive neurological disorder in which the first signs are problems with movements. 

Parnil 5 mg Tablet contains ‘Trihexyphenidyl’, which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, Parnil 5 mg Tablet also balances chemical messengers called neurotransmitters in the brain, thereby improving muscle control and reducing stiffness, thereby helping the muscles move naturally. 

In some cases, you may experience common side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Parnil 5 mg Tablet may cause drowsiness and dizziness; do not drive unless you are alert. Parnil 5 mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Parnil 5 mg Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your medicines and health conditions to rule out any side effects.

Uses of Parnil 5 mg Tablet

Treatment of Parkinson's disease.

Medicinal Benefits

Parnil 5 mg Tablet belongs to a group of medicines called anti-spasmodic agents. Parnil 5 mg Tablet is used to treat the symptoms of Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Parnil 5 mg Tablet exerts a direct inhibitory effect upon the parasympathetic nervous system. It works by relaxing the muscles and nerve impulses that control muscle functioning. Parnil 5 mg Tablet improves muscle control and reduces stiffness, thereby helping the muscles move naturally. Parnil 5 mg Tablet is used as an adjuvant therapy along with levodopa to treat Parkinson's disease. Additionally, Parnil 5 mg Tablet is used to control drug-induced movement disorders caused by CNS drugs such as dibenzoxazepines, thioxanthenes, phenothiazines, and butyrophenones.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule.Dispersible tablet: Disperse the tablet in water and consume it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Parnil 5 mg Tablet

  • Nausea
  • Vomiting
  • Dizziness
  • Constipation
  • Weakness 
  • Headache
  • Dry mouth
  • Decreased urination
  • Drowsiness
  • Feeling nervous or restless

Drug Warnings

Do not take Parnil 5 mg Tablet if you are allergic to any of its contents or if you have narrow-angle glaucoma. Do not discontinue Parnil 5 mg Tablet on your own. Inform your doctor if you have glaucoma, prostate problems, urination problems, stomach ulcers, acidity, myasthenia gravis (muscle problems), tardive dyskinesia (involuntary facial movements), alcoholism, high blood pressure, heart, liver or kidney problems. Talk to your doctor immediately if you experience hallucinations. Consult your doctor if you are pregnant or breastfeeding. Parnil 5 mg Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Parnil 5 mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Parnil 5 mg Tablet as it could lead to increased drowsiness and dizziness.

Drug Interactions

Drug-Drug Interactions: Parnil 5 mg Tablet may have interaction with antipsychotic (aripiprazole, lurasidone, olanzapine, risperidone, quetiapine, trifluoperazine), MAO inhibitor (rasagiline), antihistamine (diphenhydramine), anti-cholinergic (benztropine), anti-convulsant (clonazepam, lamotrigine, pregabalin), anti-depressants (escitalopram, duloxetine) anti-anxiety (alprazolam), and mild pain killers/fever-reducing agent (acetaminophen).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have arrhythmia (irregular heartbeats), autonomic neuropathy (nerve damage), gastrointestinal obstruction, glaucoma, urinary obstruction, infectious diarrhoea, tardive dyskinesia (involuntary facial movements), psychoses, high blood pressure, or fever.

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • LURASIDONE
  • OLANZAPINE
  • RISPERIDONE
  • QUETIAPINE
  • TRIFLUOPERAZINE
  • RASAGILINE
  • DIPHENHYDRAMINE
  • BENZTROPINE MESYLATE
  • CLONAZEPAM
  • LAMOTRIGINE
  • PREGABALIN
  • ESCITALOPRAM
  • DULOXETINE
  • ALPRAZOLAM
  • ACETAMINOPHEN

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate and magnesium. 
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Special Advise

  • Take Parnil 5 mg Tablet at least 2 hours after taking ketoconazole and antidiarrheal medicines as it may prevent the full absorption of trihexyphenidyl. Besides this, Parnil 5 mg Tablet may prevent the complete absorption of antifungal agents like ketoconazole when these medicines are taken together.

  • Parnil 5 mg Tablet can cause decreased sweating, resulting in a rise in body temperature (hyperthermia). This profound side effect is more significant in hot weather, so it is advisable to drink plenty of water, especially in summer. However, kidney patients should consult a doctor before consuming any fluid.

  • Take special care with your dental hygiene while using Parnil 5 mg Tablet (like brushing, and flossing) and have regular dental check-ups.

Disease/Condition Glossary

Parkinson’s disease: It is a progressive neurological disorder in which the first signs are problems with movements. Dopamine is a naturally occurring neurotransmitter in the brain which is reduced or absent in people with Parkinson’s disease. Due to this, problems arise with smooth and coordinated movements. Symptoms include decreased ability to smell, stooped posture, changes in voice, constipation, small/ cramped handwriting, tremors, slow movements, stiffness of arms, legs, trunk, and balance problems. 

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Parnil 5 mg Tablet as it may cause increased dizziness and drowsiness.

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Pregnancy

Caution

Parnil 5 mg Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Parnil 5 mg Tablet passes into breastmilk. Consult your doctor if you are breastfeeding.

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Driving

Unsafe

Parnil 5 mg Tablet may cause dizziness, drowsiness and blurred vision. Avoid driving and handling machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Parnil 5 mg Tablet is not recommended for use in children, as safety and effectiveness have not been established.

Country of origin

INDIA

Manufacturer/Marketer address

8/3, Asaf Ali Road, New Delhi-110002
Other Info - PAR0174

Author Details

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FAQs

Parnil 5 mg Tablet belongs to a group of medicines called anti-spasmodic agents used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders).
Parnil 5 mg Tablet works by relaxing the muscles and nerve impulses that control muscle functioning. It improves muscle control and reduces the stiffness, thereby helps the muscles move naturally.
Dry mouth could be a side-effect of Parnil 5 mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Parnil 5 mg Tablet should be used with caution during hot weather as it may increase the chance of having a heat stroke. Inform your doctor if you have heat intolerance or fever.
Antidepressants should be avoided while taking Parnil 5 mg Tablet as it might increase sedative effects. Consult your doctor before taking Parnil 5 mg Tablet if you are using depressants.
Hallucination is a medical condition in which the person may feel, hear or believe things that are not true, see things that are not there, or feel unusually suspicious or confused. Parnil 5 mg Tablet may cause hallucinations in some cases if taken for a prolonged time. So, if you experience hallucinations while taking Parnil 5 mg Tablet , please talk to your doctor immediately.
Constipation may occur as a side-effect of Parnil 5 mg Tablet . Try eating foods that encourage a bowel movement. Consult your doctor if you experience excessive constipation.
Consult your doctor before taking Parnil 5 mg Tablet if you have glaucoma. Parnil 5 mg Tablet is contraindicated in patients with narrow-angle glaucoma. Parnil 5 mg Tablet may cause blindness on long-term use in case of patients with narrow-angle glaucoma.

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