Epsinil 5mg Tablet

Epsinil 5mg Tablet is used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Parkinson’s disease is a progressive neurological disorder in which the first signs are problems with movements. 

Epsinil 5mg Tablet contains ‘Trihexyphenidyl’, which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, Epsinil 5mg Tablet also balances chemical messengers called neurotransmitters in the brain, thereby improving muscle control and reducing stiffness, thereby helping the muscles move naturally. 

In some cases, you may experience common side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Epsinil 5mg Tablet may cause drowsiness and dizziness; do not drive unless you are alert. Epsinil 5mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Epsinil 5mg Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your medicines and health conditions to rule out any side effects.

Epsinil 5mg Tablet belongs to a group of medicines called anti-spasmodic agents. Epsinil 5mg Tablet is used to treat the symptoms of Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Epsinil 5mg Tablet exerts a direct inhibitory effect upon the parasympathetic nervous system. It works by relaxing the muscles and nerve impulses that control muscle functioning. Epsinil 5mg Tablet improves muscle control and reduces stiffness, thereby helping the muscles move naturally. Epsinil 5mg Tablet is used as an adjuvant therapy along with levodopa to treat Parkinson's disease. Additionally, Epsinil 5mg Tablet is used to control drug-induced movement disorders caused by CNS drugs such as dibenzoxazepines, thioxanthenes, phenothiazines, and butyrophenones.

• Nausea
• Vomiting
• Dizziness
• Constipation
• Weakness 
• Headache
• Dry mouth
• Decreased urination
• Drowsiness
• Feeling nervous or restless

Do not take Epsinil 5mg Tablet if you are allergic to any of its contents or if you have narrow-angle glaucoma. Do not discontinue Epsinil 5mg Tablet on your own. Inform your doctor if you have glaucoma, prostate problems, urination problems, stomach ulcers, acidity, myasthenia gravis (muscle problems), tardive dyskinesia (involuntary facial movements), alcoholism, high blood pressure, heart, liver or kidney problems. Talk to your doctor immediately if you experience hallucinations. Consult your doctor if you are pregnant or breastfeeding. Epsinil 5mg Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Epsinil 5mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Epsinil 5mg Tablet as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions: Epsinil 5mg Tablet may have interaction with antipsychotic (aripiprazole, lurasidone, olanzapine, risperidone, quetiapine, trifluoperazine), MAO inhibitor (rasagiline), antihistamine (diphenhydramine), anti-cholinergic (benztropine), anti-convulsant (clonazepam, lamotrigine, pregabalin), anti-depressants (escitalopram, duloxetine) anti-anxiety (alprazolam), and mild pain killers/fever-reducing agent (acetaminophen).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have arrhythmia (irregular heartbeats), autonomic neuropathy (nerve damage), gastrointestinal obstruction, glaucoma, urinary obstruction, infectious diarrhoea, tardive dyskinesia (involuntary facial movements), psychoses, high blood pressure, or fever.

• ARIPIPRAZOLE
• LURASIDONE
• OLANZAPINE
• RISPERIDONE
• QUETIAPINE
• TRIFLUOPERAZINE
• RASAGILINE
• DIPHENHYDRAMINE
• BENZTROPINE MESYLATE
• CLONAZEPAM
• LAMOTRIGINE
• PREGABALIN
• ESCITALOPRAM
• DULOXETINE
• ALPRAZOLAM
• ACETAMINOPHEN

• Maintain a healthy diet and exercise regularly.
• Include a diet rich in iron, folate and magnesium. 
• Regularly attend therapy sessions.
• Perform meditation and yoga.
• Follow a regular sleep pattern.
• Avoid smoking and alcohol consumption.
• Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

• Take Epsinil 5mg Tablet at least 2 hours after taking ketoconazole and antidiarrheal medicines as it may prevent the full absorption of trihexyphenidyl. Besides this, Epsinil 5mg Tablet may prevent the complete absorption of antifungal agents like ketoconazole when these medicines are taken together.

• Epsinil 5mg Tablet can cause decreased sweating, resulting in a rise in body temperature (hyperthermia). This profound side effect is more significant in hot weather, so it is advisable to drink plenty of water, especially in summer. However, kidney patients should consult a doctor before consuming any fluid.

• Take special care with your dental hygiene while using Epsinil 5mg Tablet (like brushing, and flossing) and have regular dental check-ups.

Parkinson’s disease: It is a progressive neurological disorder in which the first signs are problems with movements. Dopamine is a naturally occurring neurotransmitter in the brain which is reduced or absent in people with Parkinson’s disease. Due to this, problems arise with smooth and coordinated movements. Symptoms include decreased ability to smell, stooped posture, changes in voice, constipation, small/ cramped handwriting, tremors, slow movements, stiffness of arms, legs, trunk, and balance problems.