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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:31 PM IST
Pabreca 125 mg Capsule is an anti-cancer medicine used in the treatment of certain types of breast cancer. This medicine contains palbociclid which works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Common side effects include weakness, loss of appetite, infections and dry skin.
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Composition :

PALBOCICLIB-125MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Pabreca 125 mg Capsule

Pabreca 125 mg Capsule belongs to the group of anti-cancer drugs used to treat certain types of breast cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body. Breast cancer is cancer that forms in the cells of the breast. It can form in the lobules, ducts or tubules of the breast or in the breast tissue itself.

Pabreca 125 mg Capsule contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Pabreca 125 mg Capsule is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer. 

Take Pabreca 125 mg Capsule as prescribed. In some cases, Pabreca 125 mg Capsule may cause certain common side effects such as weakness, loss of appetite, infections and dry skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components. Do not take Pabreca 125 mg Capsule if you are pregnant or breastfeeding. Pabreca 125 mg Capsule may cause tiredness, so drive only if you are alert. Pabreca 125 mg Capsule is not recommended for use in children below 18years. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Pabreca 125 mg Capsule

Treatment of Breast Cancer

Medicinal Benefits

Pabreca 125 mg Capsule is an anti-cancer drug used in the treatment of a particular type of breast cancer that is hormone receptor-positive and human epidermal growth factor receptor-2-negative. Pabreca 125 mg Capsule works by blocking the production of proteins called cyclin-dependent kinase 4 and 6 that are responsible for cell growth and division. By blocking them, Pabreca 125 mg Capsule nips cell growth in the bud and prevents cancer cells from spreading further. Thus, Pabreca 125 mg Capsule helps treat breast cancer.

Side Effects of Pabreca 125 mg Capsule

  • Loss of appetite
  • Dry skin
  • Weakness
  • Infection
  • Hair loss
  • Fever
  • Inflammation of the mouth and lips

Directions for Use

Take Pabreca 125 mg Capsule preferably with a meal. Swallow it as a whole with water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take St. John's wort or grapefruit/grapefruit juice with Pabreca 125 mg Capsule . It is advisable to inform the doctor if you are allergic to any of its components. Do not take Pabreca 125 mg Capsule if you are pregnant or breastfeeding. Pabreca 125 mg Capsule may cause tiredness, so drive only if you are alert. Pabreca 125 mg Capsule is not recommended for use in children below 18years. If you experience any signs or symptoms of infections, inform your doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Consult your doctor immediately if you experience symptoms such as dry cough, chest pain, difficulty breathing or shortness of breath as it could be an indication of lung inflammation

Therapeutic Class

CHEMOTHERAPY

Drug-Drug Interactions

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PalbociclibCladribine
Severe
PalbociclibMorphine
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.
  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

What if I have taken an overdose of Pabreca 125 mg Capsule

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, and neutropenia (low neutrophil levels). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
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Alcohol

Caution

It is not recommended to use alcohol with Pabreca 125 mg Capsule . Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Pabreca 125 mg Capsule is not recommended for use in pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Pabreca 125 mg Capsule is not recommended during breastfeeding. Please consult your doctor in case of any concerns.

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Driving

Caution

Pabreca 125 mg Capsule may cause tiredness and lethargy, which may affect your ability to drive. Do not drive if you experience any side effects after using Pabreca 125 mg Capsule .

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Liver

Caution

Exercise caution before using Pabreca 125 mg Capsule in case of established liver disease. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Pabreca 125 mg Capsule in case of established kidney disease. Please consult your doctor to address any concerns.

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Children

Unsafe

Pabreca 125 mg Capsule is not recommended for use in children under 18 years of age. Please consult your doctor in case of any concerns.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3Rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country Of Origin: India
Other Info - PAB0008

Author Details

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FAQs

Pabreca 125 mg Capsule belongs to the group of anti-cancer drugs used to treat certain types of breast cancer.
Pabreca 125 mg Capsule works blocking proteins responsible for cell growth and division, thereby arresting the progression of cancer cells.
Do not stop taking Pabreca 125 mg Capsule on your own. You are advised to take Pabreca 125 mg Capsule for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Pabreca 125 mg Capsule .
A fibroadenoma is a benign state. Pabreca 125 mg Capsule is indicated only in case of cancers. Please consult your doctor in case of any concerns.
Pabreca 125 mg Capsule can reduce fertility in men. Therefore, consider sperm preservation before starting Pabreca 125 mg Capsule if you wish to father a child in the future. Effects on female fertility have not been established. Please consult your doctor before using Pabreca 125 mg Capsule .
Pabreca 125 mg Capsule may reduce white blood cell count, thereby weakening the immune system. This might increase your risk of infections. If you notice any signs or symptoms of infections, consult your doctor.
Pabreca 125 mg Capsule is a type of targeted cancer drug. It is a treatment for breast cancer that is oestrogen receptor-positive (ER+) and human epidermal growth factor receptor-negative (HER2 -).
The duration of taking Pabreca 125 mg Capsule varies from person to person. You take it in cycles (21 days on, 7 days off.), and as long as it's working and manageable, you continue the treatment. Your healthcare team will monitor your progress and adjust the treatment plan as needed.
Most side effects associated with Pabreca 125 mg Capsule are temporary and can be effectively managed. However, certain side effects may persist or have a lasting impact in some cases. Common reversible side effects include fatigue, nausea, and hair loss, which typically resolve once treatment is stopped. In rare instances, more serious and potentially irreversible side effects may occur, such as permanent hair loss, increased infection risk, or heart problems. Regular monitoring and open communication with your healthcare team are essential to mitigate these risks and address any concerns that may arise during treatment.
Yes, Pabreca 125 mg Capsule treatment requires blood count monitoring. If neutropenia is mild in the first six cycles, monitor blood counts every 3 months afterwards. This monitoring schedule helps healthcare providers track potential changes in blood counts and adjust treatment accordingly.
Take Pabreca 125 mg Capsule exactly as your healthcare provider tells you. Swallow the capsule whole with water on an empty stomach at the same time each day. Follow the treatment schedule.
While using Pabreca 125 mg Capsule , birth control is necessary to prevent pregnancy. Female patients must take a pregnancy test before starting treatment and use birth control during treatment and for at least 3 weeks after the final dose. Male patients, along with their partners, should also use birth control during treatment and for 3 months after the final dose. It's crucial to inform your doctor if you're pregnant, plan to become pregnant, or plan to father a child so they can guide you on the appropriate measures to take.
While women's fertility may not be affected, Pabreca 125 mg Capsule can decrease fertility in men. Men taking palbociclib may want to talk to their treatment team about sperm preservation before starting treatment.
In some cases, side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or seek emergency medical treatment: fever, chills, or signs of infection; difficulty breathing or shortness of breath; cough with or without mucus; chest pain; dizziness; fast, irregular, or pounding heartbeat; weakness; unusual bleeding or bruising; nosebleeds; or redness, pain, swelling, or blisters on the palms of your hands or soles of your feet, as well as skin blistering, peeling, or redness.

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