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Pabreca 125 mg Capsule 21's

Pabreca 125 mg Capsule 21's

Prescription drug
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Consult Doctor

Manufacturer/Marketer

Lupin Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Pabreca 125 mg Capsule

Pabreca 125 mg Capsule belongs to the group of anti-cancer drugs used to treat certain types of breast cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body. Breast cancer is cancer that forms in the cells of the breast. It can form in the lobules, ducts or tubules of the breast or in the breast tissue itself.

Pabreca 125 mg Capsule contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Pabreca 125 mg Capsule is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer. 

Take Pabreca 125 mg Capsule as prescribed. In some cases, Pabreca 125 mg Capsule may cause certain common side effects such as weakness, loss of appetite, infections and dry skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components. Do not take Pabreca 125 mg Capsule if you are pregnant or breastfeeding. Pabreca 125 mg Capsule may cause tiredness, so drive only if you are alert. Pabreca 125 mg Capsule is not recommended for use in children below 18years. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Pabreca 125 mg Capsule

Treatment of Breast Cancer

Medicinal Benefits

Pabreca 125 mg Capsule is an anti-cancer drug used in the treatment of a particular type of breast cancer that is hormone receptor-positive and human epidermal growth factor receptor-2-negative. Pabreca 125 mg Capsule works by blocking the production of proteins called cyclin-dependent kinase 4 and 6 that are responsible for cell growth and division. By blocking them, Pabreca 125 mg Capsule nips cell growth in the bud and prevents cancer cells from spreading further. Thus, Pabreca 125 mg Capsule helps treat breast cancer.

Directions for Use

Take Pabreca 125 mg Capsule preferably with a meal. Swallow it as a whole with water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pabreca 125 mg Capsule

  • Loss of appetite
  • Dry skin
  • Weakness
  • Infection
  • Hair loss
  • Fever
  • Inflammation of the mouth and lips

Drug Warnings

Do not take St. John's wort or grapefruit/grapefruit juice with Pabreca 125 mg Capsule . It is advisable to inform the doctor if you are allergic to any of its components. Do not take Pabreca 125 mg Capsule if you are pregnant or breastfeeding. Pabreca 125 mg Capsule may cause tiredness, so drive only if you are alert. Pabreca 125 mg Capsule is not recommended for use in children below 18years. If you experience any signs or symptoms of infections, inform your doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Consult your doctor immediately if you experience symptoms such as dry cough, chest pain, difficulty breathing or shortness of breath as it could be an indication of lung inflammation

Drug Interactions

Drug-DrugInteractions: Pabreca 125 mg Capsule may interact antiviral/anti-HIV drug (lopinavir, ritonavir, nelfinavir, telaprevir, saquinavir), antidepressant (St John’s wort and nefazodone), antifungals (voriconazole, itraconazole, ketoconazole, posaconazole), antibiotics (clarithromycin, telithromycin) anti-rheumatoid drug (abatacept), heart medicine (quinidine), anti-gout medicine (colchicine), anaesthetics (alfentanyl and fentanyl), immunosuppressants (tacrolimus, cyclosporine), antipsychotics (pimozide) and anti-migraine drugs (dihydroergotamine, ergotamine).

Drug-Food Interactions: Pabreca 125 mg Capsule may interact with grapefruit and grapefruit juice.

Drug-Disease Interactions: Pabreca 125 mg Capsule should be used with caution in patients with a known hypersensitivity disorder, HIV, epilepsy, lactose intolerance, kidney disease, liver disease, lung or breathing disorders, hypertension, diabetes, heart disease, gout or a disease of the veins.

Drug-Drug Interactions Checker List

  • RITONAVIR
  • NELFINAVIR
  • SAQUINAVIR
  • LOPINAVIR
  • TELAPREVIR
  • ITRACONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • POSACONAZOLE
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • ABATACEPT
  • QUINIDINE
  • COLCHICINE
  • ALFENTANIL
  • FENTANYL
  • TACROLIMUS
  • CYCLOSPORINE
  • PIMOZIDE
  • ERGOTAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.
  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Special Advise

  • Discuss contraception with your doctor while taking Pabreca 125 mg Capsule .
  • People on treatment with Pabreca 125 mg Capsule should use additional contraception (barrier method such as condoms). Contraception should be continued 3 weeks post-treatment for women and 14 weeks post-treatment for men.
  • You may want to consider sperm storage before starting Pabreca 125 mg Capsule . Seek counsel on the same from a qualified healthcare individual and/or sperm bank. 
  • Regular complete blood count monitoring is advised.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer that develops in breast cells. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm. 

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Alcohol

Caution

It is not recommended to use alcohol with Pabreca 125 mg Capsule . Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Pabreca 125 mg Capsule is not recommended for use in pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Pabreca 125 mg Capsule is not recommended during breastfeeding. Please consult your doctor in case of any concerns.

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Driving

Caution

Pabreca 125 mg Capsule may cause tiredness and lethargy, which may affect your ability to drive. Do not drive if you experience any side effects after using Pabreca 125 mg Capsule .

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Liver

Caution

Exercise caution before using Pabreca 125 mg Capsule in case of established liver disease. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Pabreca 125 mg Capsule in case of established kidney disease. Please consult your doctor to address any concerns.

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Children

Unsafe

Pabreca 125 mg Capsule is not recommended for use in children under 18 years of age. Please consult your doctor in case of any concerns.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3Rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country Of Origin: India
Other Info - PAB0008

Author Details

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FAQs

Pabreca 125 mg Capsule belongs to the group of anti-cancer drugs used to treat certain types of breast cancer.
Pabreca 125 mg Capsule works blocking proteins responsible for cell growth and division, thereby arresting the progression of cancer cells.
Do not stop taking Pabreca 125 mg Capsule on your own. You are advised to take Pabreca 125 mg Capsule for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Pabreca 125 mg Capsule .
A fibroadenoma is a benign state. Pabreca 125 mg Capsule is indicated only in case of cancers. Please consult your doctor in case of any concerns.
Pabreca 125 mg Capsule can reduce fertility in men. Therefore, consider sperm preservation before starting Pabreca 125 mg Capsule if you wish to father a child in the future. Effects on female fertility have not been established. Please consult your doctor before using Pabreca 125 mg Capsule .
Pabreca 125 mg Capsule may reduce white blood cell count, thereby weakening the immune system. This might increase your risk of infections. If you notice any signs or symptoms of infections, consult your doctor.

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