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Palbace 125 mg Tablet 21's

Palbace 125 mg Tablet 21's

Prescription drug
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Manufacturer/Marketer

Pfizer Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Palbace 125 mg Tablet

Palbace 125 mg Tablet belongs to the group of anti-cancer drugs used to treat certain types of breast cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body. Breast cancer is cancer that forms in the cells of the breast. It can form in the lobules, ducts or tubules of the breast or in the breast tissue itself.

Palbace 125 mg Tablet contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Palbace 125 mg Tablet is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer. 

Take Palbace 125 mg Tablet as prescribed. In some cases, Palbace 125 mg Tablet may cause certain common side effects such as weakness, loss of appetite, infections and dry skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components. Do not take Palbace 125 mg Tablet if you are pregnant or breastfeeding. Palbace 125 mg Tablet may cause tiredness, so drive only if you are alert. Palbace 125 mg Tablet is not recommended for use in children below 18years. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Palbace 125 mg Tablet

Treatment of Breast Cancer

Medicinal Benefits

Palbace 125 mg Tablet is an anti-cancer drug used in the treatment of a particular type of breast cancer that is hormone receptor-positive and human epidermal growth factor receptor-2-negative. Palbace 125 mg Tablet works by blocking the production of proteins called cyclin-dependent kinase 4 and 6 that are responsible for cell growth and division. By blocking them, Palbace 125 mg Tablet nips cell growth in the bud and prevents cancer cells from spreading further. Thus, Palbace 125 mg Tablet helps treat breast cancer.

Directions for Use

Take Palbace 125 mg Tablet preferably with a meal. Swallow it as a whole with water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Palbace 125 mg Tablet

  • Loss of appetite
  • Dry skin
  • Weakness
  • Infection
  • Hair loss
  • Fever
  • Inflammation of the mouth and lips

Drug Warnings

Do not take St. John's wort or grapefruit/grapefruit juice with Palbace 125 mg Tablet . It is advisable to inform the doctor if you are allergic to any of its components. Do not take Palbace 125 mg Tablet if you are pregnant or breastfeeding. Palbace 125 mg Tablet may cause tiredness, so drive only if you are alert. Palbace 125 mg Tablet is not recommended for use in children below 18years. If you experience any signs or symptoms of infections, inform your doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Consult your doctor immediately if you experience symptoms such as dry cough, chest pain, difficulty breathing or shortness of breath as it could be an indication of lung inflammation

Drug Interactions

Drug-DrugInteractions: Palbace 125 mg Tablet may interact antiviral/anti-HIV drug (lopinavir, ritonavir, nelfinavir, telaprevir, saquinavir), antidepressant (St John’s wort and nefazodone), antifungals (voriconazole, itraconazole, ketoconazole, posaconazole), antibiotics (clarithromycin, telithromycin) anti-rheumatoid drug (abatacept), heart medicine (quinidine), anti-gout medicine (colchicine), anaesthetics (alfentanyl and fentanyl), immunosuppressants (tacrolimus, cyclosporine), antipsychotics (pimozide) and anti-migraine drugs (dihydroergotamine, ergotamine).

Drug-Food Interactions: Palbace 125 mg Tablet may interact with grapefruit and grapefruit juice.

Drug-Disease Interactions: Palbace 125 mg Tablet should be used with caution in patients with a known hypersensitivity disorder, HIV, epilepsy, lactose intolerance, kidney disease, liver disease, lung or breathing disorders, hypertension, diabetes, heart disease, gout or a disease of the veins.

Drug-Drug Interactions Checker List

  • RITONAVIR
  • NELFINAVIR
  • SAQUINAVIR
  • LOPINAVIR
  • TELAPREVIR
  • ITRACONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • POSACONAZOLE
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • ABATACEPT
  • QUINIDINE
  • COLCHICINE
  • ALFENTANIL
  • FENTANYL
  • TACROLIMUS
  • CYCLOSPORINE
  • PIMOZIDE
  • ERGOTAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.
  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Special Advise

  • Discuss contraception with your doctor while taking Palbace 125 mg Tablet .
  • People on treatment with Palbace 125 mg Tablet should use additional contraception (barrier method such as condoms). Contraception should be continued 3 weeks post-treatment for women and 14 weeks post-treatment for men.
  • You may want to consider sperm storage before starting Palbace 125 mg Tablet . Seek counsel on the same from a qualified healthcare individual and/or sperm bank. 
  • Regular complete blood count monitoring is advised.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer that develops in breast cells. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm. 

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Alcohol

Caution

It is not recommended to use alcohol with Palbace 125 mg Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Palbace 125 mg Tablet is not recommended for use in pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Palbace 125 mg Tablet is not recommended during breastfeeding. Please consult your doctor in case of any concerns.

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Driving

Caution

Palbace 125 mg Tablet may cause tiredness and lethargy, which may affect your ability to drive. Do not drive if you experience any side effects after using Palbace 125 mg Tablet .

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Liver

Caution

Exercise caution before using Palbace 125 mg Tablet in case of established liver disease. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Palbace 125 mg Tablet in case of established kidney disease. Please consult your doctor to address any concerns.

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Children

Unsafe

Palbace 125 mg Tablet is not recommended for use in children under 18 years of age. Please consult your doctor in case of any concerns.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18Th Floor , Plot No. C-70, €˜G’ Block , Bandra Kurla Complex, Bandra East , Mumbai €“ 400051
Other Info - PAL0220

Author Details

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FAQs

Palbace 125 mg Tablet belongs to the group of anti-cancer drugs used to treat certain types of breast cancer.
Palbace 125 mg Tablet works blocking proteins responsible for cell growth and division, thereby arresting the progression of cancer cells.
Do not stop taking Palbace 125 mg Tablet on your own. You are advised to take Palbace 125 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Palbace 125 mg Tablet .
A fibroadenoma is a benign state. Palbace 125 mg Tablet is indicated only in case of cancers. Please consult your doctor in case of any concerns.
Palbace 125 mg Tablet can reduce fertility in men. Therefore, consider sperm preservation before starting Palbace 125 mg Tablet if you wish to father a child in the future. Effects on female fertility have not been established. Please consult your doctor before using Palbace 125 mg Tablet .
Palbace 125 mg Tablet may reduce white blood cell count, thereby weakening the immune system. This might increase your risk of infections. If you notice any signs or symptoms of infections, consult your doctor.

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