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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:27 PM IST

Oxalip Inj 100Mg * is used to treat Colon and rectal cancer. It contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer. Sometimes, Oxalip Inj 100Mg * may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding.

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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Cytogen

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Oxalip Inj 100Mg *

Oxalip Inj 100Mg * belongs to the group of medicines called platinum-containing antineoplastic agents used alone or in combination with other anti-cancer medicines to treat cancer of the large bowel/intestine (advanced colon or colorectal cancer).

Oxalip Inj 100Mg * contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer.

In some cases, Oxalip Inj 100Mg * may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Oxalip Inj 100Mg * if you are breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Oxalip Inj 100Mg *. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Oxalip Inj 100Mg *

Treatment of Colon and rectal cancer

Medicinal Benefits

Oxalip Inj 100Mg * contains Oxaliplatin, which belongs to the group of medicines called platinum-containing antineoplastic agents used to treat stage III colon cancer after complete removal of the primary tumour and metastatic cancer of the colon and rectum. It is used in combination with other anti-cancer medicines, such as 5-fluorouracil and folinic acid. Oxalip Inj 100Mg * works by killing the cancer cells. Thereby, it helps treat cancer. Oxalip Inj 100Mg * may also be used with other medicines to prevent colon cancer from spreading in patients who have had surgery to remove the tumour.

Directions for Use

Oxalip Inj 100Mg * will be administered by a qualified physician; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oxalip Inj 100Mg *

  • Mild nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Peripheral neuropathy
  • Fatigue
  • Back pain
  • Stomach pain

Drug Warnings

Do not use Oxalip Inj 100Mg * if you are allergic to any of its components, if you are breastfeeding, have a low blood cell count, have severe kidney problems, tingling and numbness in the fingers/toes, and have difficulty performing fragile tasks, such as buttoning clothes. Inform the doctor if you ever suffered an allergic reaction to platinum-containing medicines, have mild/moderate kidney problems, liver problems or abnormal liver function tests during therapy, or heart disorders like prolongation of the QT interval (abnormal electrical signal), an irregular heartbeat, or a family history of heart problems. Seek immediate medical attention if you experience symptoms of an allergic reaction (rash, itching, hives, reddening of the skin, hoarseness, difficulty breathing or swallowing, feeling as if your throat is closing, dizziness, swelling of the lips and tongue, lightheadedness, or fainting), unpleasant sensation in the throat, rhabdomyolysis (muscle pain and swelling), nerve problems (sensitivity to cold temperature or cold objects, pain, tingling or burning sensation), Posterior Reversible Encephalopathy Syndrome (headache, confusion, seizures, vision problems), myelosuppression (chills or shivering, burning or pain on urination, pain on swallowing, sore throat, cough with mucus, persistent diarrhoea), lung problems (shortness of breath, wheezing, cough), or bleeding problems (vomit that looks like coffee grounds or bloody vomit, pink or brown urine, weakness, dizziness, changes in speech, confusion, unexplained bleeding or dark-coloured/tarry stools).

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking medicines that prolong QT interval (antiarrhythmic agents), nephrotoxic products, or anti-coagulants.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform the doctor if you have an infection, lung, liver or kidney problems, bleeding problems, heart problems (long QT syndrome, irregular/slow heartbeat), or changes in electrolyte levels.

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Special Advise

  • Women must use reliable contraception during treatment and for nine months after receiving the last dose.
  • Male patients are advised not to father a child during treatment and for six months after the last dose. Use effective contraception during this time.
  • If you are due to undergo any surgery, including dental surgery, inform the doctor/dentist that you are on treatment with Oxalip Inj 100Mg *.
  • Avoid eating or drinking anything that is colder than room temperature for five days after receiving each dose of Oxalip Inj 100Mg *. To reduce side effects caused by cold temperature-cover yourself with a blanket while getting treatment with Oxalip Inj 100Mg *, wear warm clothing in cold weather at all times, cover your mouth and nose with a scarf and wear gloves whilst touching cold objects. Drink fluid at room/warm temperature and always drink through a straw. Avoid using ice and AC, touching cold metals, and breathing deeply when exposed to cold air.

Disease/Condition Glossary

Colon and rectal cancer: It is a cancer of the colon or rectum. Colorectal cancer is the growth of cells that form in the lower end of the digestive tract. Most of these cancers begin as polyps (non-cancerous growths). Symptoms may include abdominal discomfort, blood in the stool, and changes in bowel habits like constipation or diarrhoea.

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Alcohol

Consult your doctor

It is not known if alcohol affects Oxalip Inj 100Mg *. Please consult your doctor.

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Pregnancy

Unsafe

Oxalip Inj 100Mg * may cause foetal harm. Therefore, avoid becoming pregnant during treatment with Oxalip Inj 100Mg *.

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Oxalip Inj 100Mg * and for three months after the last dose.

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Driving

Caution

Oxalip Inj 100Mg * may cause dizziness or vision problems. Avoid driving or operating machinery if you experience any side effects that might lessen your ability to do so.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Oxalip Inj 100Mg *.

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Kidney

Caution

Oxalip Inj 100Mg * should not be used if you have severe kidney disease. If you have mild or moderate kidney disease, inform your doctor before receiving Oxalip Inj 100Mg *.

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Children

Unsafe

Oxalip Inj 100Mg * is not recommended for children as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Cytogen Pharmaceuticals India Pvt. Ltd., 105, Anupam Plaza, 6, Local shopping Complex Gazipur, Delhi-96.
Other Info - OXA0019

Author Details

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FAQs

Oxalip Inj 100Mg * is used to treat Colon and rectal cancer.
Oxalip Inj 100Mg * works by killing the cancer cells. Thereby, it helps treat cancer.
Oxalip Inj 100Mg * may have an anti-fertility effect, which could be irreversible. Therefore, male patients should seek medical advice on the conservation of sperm prior to treatment with Oxalip Inj 100Mg *.
Avoid drinking or eating anything colder than room temperature. Do not touch any cold objects, wash your hands in cold water, go near air conditioners or freezers, or go outside in cold weather unless absolutely necessary for five days after you receive each dose of Oxalip Inj 100Mg *. Wear a hat, gloves, and a scarf, and cover your mouth and nose if you must go outside in cold weather.
Oxalip Inj 100Mg * may decrease the ability to fight infections due to reduced white blood cells. Stay away from sick people during treatment with Oxalip Inj 100Mg *.
Oxalip Inj 100Mg * is administered to you through an intravenous (IV) infusion. A healthcare professional usually gives it in a clinical setting.
The common side effects of Oxalip Inj 100Mg * are mild nausea, vomiting, diarrhoea, headache, peripheral neuropathy, fatigue, back pain, and stomach pain. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

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