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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Oxoplan 100 Injection is used to treat Colon and rectal cancer. It contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer. Sometimes, Oxoplan 100 Injection may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding.

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Composition :

OXALIPLATIN-100MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Oxoplan 100 Injection

Oxoplan 100 Injection belongs to the group of medicines called platinum-containing antineoplastic agents used alone or in combination with other anti-cancer medicines to treat cancer of the large bowel/intestine (advanced colon or colorectal cancer).

Oxoplan 100 Injection contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer.

In some cases, Oxoplan 100 Injection may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Oxoplan 100 Injection if you are breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Oxoplan 100 Injection. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Oxoplan 100 Injection

Treatment of Colon and rectal cancer

Directions for Use

Oxoplan 100 Injection will be administered by a qualified physician; do not self-administer.

Medicinal Benefits

Oxoplan 100 Injection contains Oxaliplatin, which belongs to the group of medicines called platinum-containing antineoplastic agents used to treat stage III colon cancer after complete removal of the primary tumour and metastatic cancer of the colon and rectum. It is used in combination with other anti-cancer medicines, such as 5-fluorouracil and folinic acid. Oxoplan 100 Injection works by killing the cancer cells. Thereby, it helps treat cancer. Oxoplan 100 Injection may also be used with other medicines to prevent colon cancer from spreading in patients who have had surgery to remove the tumour.

How Oxoplan 100 Injection Works

Oxoplan 100 Injection contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oxoplan 100 Injection

  • Mild nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Peripheral neuropathy
  • Fatigue
  • Back pain
  • Stomach pain

What if I have taken an overdose of Oxoplan 100 Injection

As Oxoplan 100 Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Oxoplan 100 Injection may cause chest pain, diarrhea, numbness or tingling in the fingers or toes, slowed breathing, slowed heartbeat, shortness of breath, tightening of the throat, vomiting, and wheezing.

Drug Warnings

Do not use Oxoplan 100 Injection if you are allergic to any of its components, if you are breastfeeding, have a low blood cell count, have severe kidney problems, tingling and numbness in the fingers/toes, and have difficulty performing fragile tasks, such as buttoning clothes. Inform the doctor if you ever suffered an allergic reaction to platinum-containing medicines, have mild/moderate kidney problems, liver problems or abnormal liver function tests during therapy, or heart disorders like prolongation of the QT interval (abnormal electrical signal), an irregular heartbeat, or a family history of heart problems. Seek immediate medical attention if you experience symptoms of an allergic reaction (rash, itching, hives, reddening of the skin, hoarseness, difficulty breathing or swallowing, feeling as if your throat is closing, dizziness, swelling of the lips and tongue, lightheadedness, or fainting), unpleasant sensation in the throat, rhabdomyolysis (muscle pain and swelling), nerve problems (sensitivity to cold temperature or cold objects, pain, tingling or burning sensation), Posterior Reversible Encephalopathy Syndrome (headache, confusion, seizures, vision problems), myelosuppression (chills or shivering, burning or pain on urination, pain on swallowing, sore throat, cough with mucus, persistent diarrhoea), lung problems (shortness of breath, wheezing, cough), or bleeding problems (vomit that looks like coffee grounds or bloody vomit, pink or brown urine, weakness, dizziness, changes in speech, confusion, unexplained bleeding or dark-coloured/tarry stools).

Drug-Drug Interactions

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OxaliplatinZiprasidone
Critical
OxaliplatinEtanercept
Severe

Drug-Drug Interactions

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OxaliplatinZiprasidone
Critical
How does the drug interact with Oxoplan 100 Injection 1's:
Combining Oxoplan 100 Injection 1's with Ziprasidone can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Oxoplan 100 Injection 1's with Ziprasidone is not recommended, please consult your doctor before taking it.
OxaliplatinEtanercept
Severe
How does the drug interact with Oxoplan 100 Injection 1's:
When Etanercept is used with Oxoplan 100 Injection 1's, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Oxoplan 100 Injection 1's and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
OxaliplatinIvabradine
Severe
How does the drug interact with Oxoplan 100 Injection 1's:
Using ivabradine together with Oxoplan 100 Injection 1's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Oxoplan 100 Injection 1's and Ivabradine, you can take these medicines together if prescribed by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
OxaliplatinHydroxychloroquine
Severe
How does the drug interact with Oxoplan 100 Injection 1's:
The combined use of Oxoplan 100 Injection 1's and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of oxalipatin and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
OxaliplatinHaloperidol
Severe
How does the drug interact with Oxoplan 100 Injection 1's:
Co-administration of Oxoplan 100 Injection 1's and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Oxoplan 100 Injection 1's and Haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
OxaliplatinAmiodarone
Severe
How does the drug interact with Oxoplan 100 Injection 1's:
Coadministration of Amiodarone together with Oxoplan 100 Injection 1's may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Oxoplan 100 Injection 1's interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.
OxaliplatinMoxifloxacin
Severe
How does the drug interact with Oxoplan 100 Injection 1's:
Using Moxifloxacin together with Oxoplan 100 Injection 1's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Oxoplan 100 Injection 1's and Moxifloxacin, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience dizziness, shortness of breath, or heart palpitations (irregular heartbeat). Do not stop using any medications without a doctor's advice.
OxaliplatinNilotinib
Severe
How does the drug interact with Oxoplan 100 Injection 1's:
Combining Oxoplan 100 Injection 1's and nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Oxoplan 100 Injection 1's and nilotinib together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
OxaliplatinBaricitinib
Severe
How does the drug interact with Oxoplan 100 Injection 1's:
Coadministration of baricitinib and Oxoplan 100 Injection 1's can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Oxoplan 100 Injection 1's if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
OxaliplatinAmisulpride
Severe
How does the drug interact with Oxoplan 100 Injection 1's:
Using amisulpride together with Oxoplan 100 Injection 1's can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Co-administration of Oxoplan 100 Injection 1's with Amisulpride can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Oxoplan 100 Injection Substitute

Substitutes safety advice
  • Oxitan Vail 50Ml

    by AYUR

    38.47per tablet
  • OXITAN 100MG INJECTION 50ML

    85.75per tablet
  • Oxyrea 100 Injection 1's

    1688.00per tablet
  • Oxitoz 100 mg Injection 1's

    4287.40per tablet
  • Oxosar-100 Injection 50 ml

    77.03per tablet
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Alcohol

Consult your doctor

It is not known if alcohol affects Oxoplan 100 Injection. Please consult your doctor.

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Pregnancy

Unsafe

Oxoplan 100 Injection may cause foetal harm. Therefore, avoid becoming pregnant during treatment with Oxoplan 100 Injection.

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Oxoplan 100 Injection and for three months after the last dose.

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Driving

Caution

Oxoplan 100 Injection may cause dizziness or vision problems. Avoid driving or operating machinery if you experience any side effects that might lessen your ability to do so.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Oxoplan 100 Injection.

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Kidney

Caution

Oxoplan 100 Injection should not be used if you have severe kidney disease. If you have mild or moderate kidney disease, inform your doctor before receiving Oxoplan 100 Injection.

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Children

Unsafe

Oxoplan 100 Injection is not recommended for children as safety and effectiveness have not been established.

FAQs

Oxoplan 100 Injection is used to treat Colon and rectal cancer.
Oxoplan 100 Injection works by killing the cancer cells. Thereby, it helps treat cancer.
Oxoplan 100 Injection may have an anti-fertility effect, which could be irreversible. Therefore, male patients should seek medical advice on the conservation of sperm prior to treatment with Oxoplan 100 Injection.
Avoid drinking or eating anything colder than room temperature. Do not touch any cold objects, wash your hands in cold water, go near air conditioners or freezers, or go outside in cold weather unless absolutely necessary for five days after you receive each dose of Oxoplan 100 Injection. Wear a hat, gloves, and a scarf, and cover your mouth and nose if you must go outside in cold weather.
Oxoplan 100 Injection may decrease the ability to fight infections due to reduced white blood cells. Stay away from sick people during treatment with Oxoplan 100 Injection.
Oxoplan 100 Injection is administered to you through an intravenous (IV) infusion. A healthcare professional usually gives it in a clinical setting.
The common side effects of Oxoplan 100 Injection are mild nausea, vomiting, diarrhoea, headache, peripheral neuropathy, fatigue, back pain, and stomach pain. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - OXO0033

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