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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 23, 2024 | 4:50 PM IST
Orzine-100 Tablet 10's is used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Besides this, it is also used to treat nausea and vomiting, anxiety before surgery, and chronic hiccups (involuntary spasms of the diaphragm). It contains Chlorpromazine, which acts by blocking dopamine, a neurotransmitter present in the brain responsible for developing schizophrenia and bipolar disorder symptoms. It rebalances dopamine to improve thinking, mood and behaviour. It also blocks the other natural substances receptors in the brain, such as histamine and muscarinic receptors, thereby preventing nausea and vomiting. In some cases, you may experience certain common side effects such as sleepiness, orthostatic hypotension (sudden lowering of blood pressure on standing), dry mouth, abnormality of voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor.
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Manufacturer/Marketer :

Pharma Fabrikon

Consume Type :

ORAL

Return Policy :

Not Returnable

About Orzine-100 Tablet 10's

Orzine-100 Tablet 10's is used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Besides this, it is also used to treat nausea and vomiting, anxiety before surgery, and chronic hiccups (involuntary spasms of the diaphragm). Schizophrenia is characterized by hallucinations symptoms (seeing or hearing things that are not real) and delusions (wrong beliefs). Manic episodes of excitement or depression characterize bipolar disorder. Orzine-100 Tablet 10's prevents the occurrence of these symptoms. 

Orzine-100 Tablet 10's contains ‘Chlorpromazine’, which is an antipsychotic drug. It acts by blocking dopamine, a neurotransmitter present in the brain responsible for developing schizophrenia and bipolar disorder symptoms. Orzine-100 Tablet 10's rebalances dopamine to improve thinking, mood and behaviour. It also blocks the other natural substances receptors in the brain, such as histamine and muscarinic receptors, thereby preventing nausea and vomiting.

Take Orzine-100 Tablet 10's as prescribed by your doctor. You are advised to take Orzine-100 Tablet 10's as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as sleepiness, orthostatic hypotension (sudden lowering of blood pressure on standing), dry mouth, abnormality of voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor. Most of these side effects of Orzine-100 Tablet 10's do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Do not take Orzine-100 Tablet 10's if you are allergic to Chlorpromazine or any other ingredients present in it. Before taking Orzine-100 Tablet 10's, talk to your doctor if you or your family have a history of blood clots, stroke or heart disease or if you are above 65 years and have a history of dementia (memory loss). Orzine-100 Tablet 10's is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Orzine-100 Tablet 10's. It is not recommended for use in children under 1 year of age. Please do not stop taking Orzine-100 Tablet 10's without your doctor’s advice, as it may lead to withdrawal symptoms.

Uses of Orzine-100 Tablet 10's

Treatment of Schizophrenia (mental illness), Bipolar disorder (manic depression).

Medicinal Benefits

Orzine-100 Tablet 10's works by helping to restore the balance of certain natural substances in the brain. The key action of Orzine-100 Tablet 10's is to block the dopamine receptors (D2) in the brain and correct dopamine's overactivity. Altogether, Orzine-100 Tablet 10's may help decrease hallucinations and help you think more clearly and positively about yourself, feel less agitated and take a more active part in everyday life. On the other hand, it also blocks histamine H1 and muscarinic M1 receptors in the vomiting centre, thereby preventing nausea and vomiting.

Side Effects of Orzine-100 Tablet 10's

  • Sleepiness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Dry mouth
  • Weight gain
  • Urinary retention
  • Constipation
  • Muscle stiffness
  • Tremor

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not crush, chew or break the tablet/capsule.Suspension/Syrup/Drops: Shake the bottle well before use. Check the label for directions and take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Orzine-100 Tablet 10's if you are allergic (hypersensitive) to any ingredients present in it. Please consult your doctor before taking Orzine-100 Tablet 10's if you are pregnant, planning to conceive and breastfeeding. The use of Orzine-100 Tablet 10's should be avoided in children and adolescents whose signs and symptoms suggest Reye’s syndrome (confusion, swelling in the brain, and liver damage). Elderly patients (above 65 years) with dementia-related psychosis (memory loss) treated with antipsychotic drugs increased the risk of death. Do not abruptly stop taking the medication, as it may cause withdrawal symptoms, especially suicidal thoughts in young adults. Before taking Orzine-100 Tablet 10's, talk to your doctor if you have a history of blood clots, alcohol or drug abuse, fits (seizures), Parkinson's disease, hypothyroidism (reduced activity of the thyroid gland), stroke or heart diseases, myasthenia gravis (a condition where muscles become easily tired and weak leading to difficulty breathing) and glaucoma (increased pressure in the eye).

Therapeutic Class

ANTIPSYCHOTICS

Drug-Drug Interactions

verifiedApollotooltip
ChlorpromazineThioridazine
Critical
ChlorpromazineDronedarone
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine and activities that can impact your mood. 

  • Exercise daily. It can also avoid the weight gain that can be a side effect of bipolar medication.

  • Practice calming techniques such as meditation and deep breathing exercises.

  • Get some sleep. Having enough sleep will help to stabilize your mood.

  • Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.

  • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.

  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils and low-fat dairy products will help to keep a person in good health and avoid the chances of nausea and vomiting.

  • One should avoid taking greasy or oily foods as this food triggers nausea and vomiting.

  • Eat cool foods instead of hot and spicy foods.

  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid make up, which has got lost due to vomiting.

Habit Forming

No

What if I have taken an overdose of Orzine-100 Tablet 10's

Do not take more than the prescribed dose of Orzine-100 Tablet 10's as it may cause overdose. The symptoms of overdose include low body temperature, drowsiness, low blood pressure, stiffness, shaking, twisting of your limbs, unusual heart beats and coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Country of origin

India

Manufacturer/Marketer address

1/332, Otthappatti, Karuppayurani Post, Madurai, Tamil Nadu 625020
Other Info - ORZ0020

Author Details

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