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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 22, 2024 | 7:38 PM IST
Oneova 5mg Tablet is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). It contains Letrozole, which prevents the growth of cancer cells. Thereby, it helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts. It may cause certain common side effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition

LETROZOLE-5MG

Manufacturer/Marketer

Blisson Mediplus Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Oneova 5mg Tablet

Oneova 5mg Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.
 
Oneova 5mg Tablet contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Oneova 5mg Tablet prevents the growth of cancer cells. Thereby Oneova 5mg Tablet helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

You are advised to take Oneova 5mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Oneova 5mg Tablet may cause certain common side-effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.
 
Avoid taking Oneova 5mg Tablet if you are pregnant or breastfeeding. Oneova 5mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Oneova 5mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Oneova 5mg Tablet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Oneova 5mg Tablet

Treatment of Breast cancer

Medicinal Benefits

Oneova 5mg Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors. Oneova 5mg Tablet is used to treat breast cancer in women who have gone through menopause (cessation of periods). Oneova 5mg Tablet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Oneova 5mg Tablet prevents the growth of cancer cells. Thereby, Oneova 5mg Tablet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Directions for Use

Take Oneova 5mg Tablet with or without food. Swallow Oneova 5mg Tablet as a whole with a glass of water; do not chew or break it. Take Oneova 5mg Tablet at the same time every day.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oneova 5mg Tablet

  • Hypercholesterolemia (increased cholesterol levels)
  • Tiredness
  • Weakness
  • Increased sweating
  • Feeling unwell
  • Pain in joints
  • Hot flushes (feeling of warmth)

Drug Warnings

Do not take Oneova 5mg Tablet if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods). Talk to your doctor before taking Oneova 5mg Tablet if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease. Oneova 5mg Tablet may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Oneova 5mg Tablet. Avoid taking Oneova 5mg Tablet if you are pregnant or breastfeeding. Oneova 5mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Oneova 5mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Oneova 5mg Tablet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications before taking Oneova 5mg Tablet to rule out any side-effects. 

Drug Interactions

Drug-Drug Interactions: Oneova 5mg Tablet may interact with antidepressants (citalopram, escitalopram) and anticancer (tamoxifen). 

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have high cholesterol, osteoporosis (thinning of bone), or liver disease.

Drug-Drug Interactions Checker List

  • CITALOPRAM
  • ESCITALOPRAM
  • TAMOXIFEN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.

  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.

  • Get optimal sleep; rest well.

Special Advise

  • Your doctor may advise you to regularly measure bone density before, during and after the treatment as Oneova 5mg Tablet may cause bone thinning due to reduction of estrogens in the body.

  • Oneova 5mg Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Oneova 5mg Tablet.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells which are stimulated by the female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.  

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Oneova 5mg Tablet to avoid unpleasant side effects. Alcohol intake, along with Oneova 5mg Tablet, may cause increased drowsiness.

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Pregnancy

Unsafe

Oneova 5mg Tablet is pregnancy category D medicine so, should not be taken during pregnancy.

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Breast Feeding

Unsafe

Oneova 5mg Tablet should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby.

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Driving

Caution

Oneova 5mg Tablet may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Safe if prescribed

It is safe to take Oneova 5mg Tablet if prescribed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

It is safe to take Oneova 5mg Tablet if prescribed. Please consult your doctor if you have kidney impairment or any concerns regarding this. No dosage adjustment is required for kidney patients with creatinine clearance greater than 10 mL/min.

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Children

Unsafe

Oneova 5mg Tablet should not be used by children, as the efficacy and safety have not been established.

Country of origin

India

Manufacturer/Marketer address

E-311 Eastern Business Dis, Mumbai Suburban Mumbai City Mh 400078 India
Other Info - ONE0182

Author Details

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FAQs

Oneova 5mg Tablet belongs to the group of anti-cancer medicines used to treat breast cancer in women.
Oneova 5mg Tablet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Oneova 5mg Tablet prevents the growth of cancer cells. Thereby, Oneova 5mg Tablet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.
Oneova 5mg Tablet causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.
High blood pressure could be a side-effect of Oneova 5mg Tablet. Regularly monitor blood pressure levels while taking Oneova 5mg Tablet. Consult your doctor if you regularly notice high blood pressure levels.
Do not stop taking Oneova 5mg Tablet on your own. You are advised to take Oneova 5mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Oneova 5mg Tablet.
Oneova 5mg Tablet may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Oneova 5mg Tablet.
Oneova 5mg Tablet may cause weight gain due to an increase in appetite. Eat a healthy diet and exercise regularly to maintain proper weight.
Oneova 5mg Tablet should be swallowed as a whole with water; do not crush or chew it.
Oneova 5mg Tablet can be taken with or without food.
Oneova 5mg Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Oneova 5mg Tablet is prescribed to treat breast cancer in women who have gone through menopause.
Oneova 5mg Tablet may cause high blood pressure. Therefore, irbesartan should be taken with Oneova 5mg Tablet only if prescribed by the doctor. Regularly monitor blood pressure levels while taking Oneova 5mg Tablet.
Oneova 5mg Tablet may cause eye problems like blurred vision and cataracts. Consult the doctor if you experience blurred vision or eye irritation.
Oneova 5mg Tablet may cause hot flushes leading to sweating. These symptoms usually improve during the first few months. However, if the symptoms persist or worsen, consult the doctor.
Serious side effects of Oneova 5mg Tablet are difficulty breathing, chest pain, fainting, rapid heart rate, formation of blood clots (bluish skin discolouration, or sudden arm, leg or foot pain) and rupture of a tendon. These side effects are rare and may not occur in everyone taking Oneova 5mg Tablet.
Letrozole may induce ovulation in anovulatory infertility patients and augment follicles for ovulatory women. However, it is an off-label use. Talk to the doctor if you have any concerns.
Oneova 5mg Tablet is not recommended for use during pregnancy or while breastfeeding.
The time required for Oneova 5mg Tablet to show its effects depends upon your condition and severity. Consult the doctor if you have any concerns.
If you miss a dose of Oneova 5mg Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Oneova 5mg Tablet may interact with antidepressants (citalopram, escitalopram) and anticancer medicines (tamoxifen). Let the doctor know if you are taking these medicines.
Store Oneova 5mg Tablet at room temperature, in a dry place. Keep out of sight and reach of children.

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