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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 22, 2024 | 7:38 PM IST
Macova 5 mg Tablet is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). It contains Letrozole, which prevents the growth of cancer cells. Thereby, it helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts. It may cause certain common side effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

LETROZOLE-5MG

Manufacturer/Marketer :

Gynofem Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Apr-26

About Macova 5 mg Tablet

Macova 5 mg Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.
 
Macova 5 mg Tablet contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Macova 5 mg Tablet prevents the growth of cancer cells. Thereby Macova 5 mg Tablet helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

You are advised to take Macova 5 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Macova 5 mg Tablet may cause certain common side-effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.
 
Avoid taking Macova 5 mg Tablet if you are pregnant or breastfeeding. Macova 5 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Macova 5 mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Macova 5 mg Tablet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Macova 5 mg Tablet

Treatment of Breast cancer

Medicinal Benefits

Macova 5 mg Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors. Macova 5 mg Tablet is used to treat breast cancer in women who have gone through menopause (cessation of periods). Macova 5 mg Tablet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Macova 5 mg Tablet prevents the growth of cancer cells. Thereby, Macova 5 mg Tablet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Side Effects of Macova 5 mg Tablet

  • Hypercholesterolemia (increased cholesterol levels)
  • Tiredness
  • Weakness
  • Increased sweating
  • Feeling unwell
  • Pain in joints
  • Hot flushes (feeling of warmth)

Directions for Use

Take Macova 5 mg Tablet with or without food. Swallow Macova 5 mg Tablet as a whole with a glass of water; do not chew or break it. Take Macova 5 mg Tablet at the same time every day.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Macova 5 mg Tablet if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods). Talk to your doctor before taking Macova 5 mg Tablet if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease. Macova 5 mg Tablet may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Macova 5 mg Tablet. Avoid taking Macova 5 mg Tablet if you are pregnant or breastfeeding. Macova 5 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Macova 5 mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Macova 5 mg Tablet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications before taking Macova 5 mg Tablet to rule out any side-effects. 

Therapeutic Class

CHEMOTHERAPY

Drug-Drug Interactions

verifiedApollotooltip
LetrozoleEthinylestradiol
Severe
LetrozoleConjugated Estrogens
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.

  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.

  • Get optimal sleep; rest well.

Habit Forming

No

What if I have taken an overdose of Macova 5 mg Tablet

Do not take more than the prescribed dose of Macova 5 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Macova 5 mg Tablet to avoid unpleasant side effects. Alcohol intake, along with Macova 5 mg Tablet, may cause increased drowsiness.

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Pregnancy

Unsafe

Macova 5 mg Tablet is pregnancy category D medicine so, should not be taken during pregnancy.

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Breast Feeding

Unsafe

Macova 5 mg Tablet should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby.

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Driving

Caution

Macova 5 mg Tablet may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Safe if prescribed

It is safe to take Macova 5 mg Tablet if prescribed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

It is safe to take Macova 5 mg Tablet if prescribed. Please consult your doctor if you have kidney impairment or any concerns regarding this. No dosage adjustment is required for kidney patients with creatinine clearance greater than 10 mL/min.

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Children

Unsafe

Macova 5 mg Tablet should not be used by children, as the efficacy and safety have not been established.

Country of origin

India
Other Info - MAC0506

Author Details

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FAQs

Macova 5 mg Tablet belongs to the group of anti-cancer medicines used to treat breast cancer in women.
Macova 5 mg Tablet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Macova 5 mg Tablet prevents the growth of cancer cells. Thereby, Macova 5 mg Tablet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.
Macova 5 mg Tablet causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.
High blood pressure could be a side-effect of Macova 5 mg Tablet. Regularly monitor blood pressure levels while taking Macova 5 mg Tablet. Consult your doctor if you regularly notice high blood pressure levels.
Do not stop taking Macova 5 mg Tablet on your own. You are advised to take Macova 5 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Macova 5 mg Tablet.
Macova 5 mg Tablet may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Macova 5 mg Tablet.
Macova 5 mg Tablet may cause weight gain due to an increase in appetite. Eat a healthy diet and exercise regularly to maintain proper weight.
Macova 5 mg Tablet should be swallowed as a whole with water; do not crush or chew it.
Macova 5 mg Tablet can be taken with or without food.
Macova 5 mg Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Macova 5 mg Tablet is prescribed to treat breast cancer in women who have gone through menopause.
Macova 5 mg Tablet may cause high blood pressure. Therefore, irbesartan should be taken with Macova 5 mg Tablet only if prescribed by the doctor. Regularly monitor blood pressure levels while taking Macova 5 mg Tablet.
Macova 5 mg Tablet may cause eye problems like blurred vision and cataracts. Consult the doctor if you experience blurred vision or eye irritation.
Macova 5 mg Tablet may cause hot flushes leading to sweating. These symptoms usually improve during the first few months. However, if the symptoms persist or worsen, consult the doctor.
Serious side effects of Macova 5 mg Tablet are difficulty breathing, chest pain, fainting, rapid heart rate, formation of blood clots (bluish skin discolouration, or sudden arm, leg or foot pain) and rupture of a tendon. These side effects are rare and may not occur in everyone taking Macova 5 mg Tablet.
Letrozole may induce ovulation in anovulatory infertility patients and augment follicles for ovulatory women. However, it is an off-label use. Talk to the doctor if you have any concerns.
Macova 5 mg Tablet is not recommended for use during pregnancy or while breastfeeding.
The time required for Macova 5 mg Tablet to show its effects depends upon your condition and severity. Consult the doctor if you have any concerns.
If you miss a dose of Macova 5 mg Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Macova 5 mg Tablet may interact with antidepressants (citalopram, escitalopram) and anticancer medicines (tamoxifen). Let the doctor know if you are taking these medicines.
Store Macova 5 mg Tablet at room temperature, in a dry place. Keep out of sight and reach of children.

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