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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ondafresh-MD 4 mg Disintegrating Tablet is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment or surgery. It contains Ondanestron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. It may cause side effects such as feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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rxMedicinePrescription drug

Whats That

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Composition :

ONDANSETRON-4MG

Manufacturer/Marketer :

Smart Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ondafresh-MD 4 mg Disintegrating Tablet

Ondafresh-MD 4 mg Disintegrating Tablet belongs to a group of medications called ' anti-emetics' primarily used in the prevention of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit while vomiting is the natural response to the body to forcefully discharge the stomach contents.

Ondafresh-MD 4 mg Disintegrating Tablet contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Ondafresh-MD 4 mg Disintegrating Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Take Ondafresh-MD 4 mg Disintegrating Tablet as prescribed. Your doctor will advise you on how often you take Ondafresh-MD 4 mg Disintegrating Tablet based on your medical condition. A person taking Ondafresh-MD 4 mg Disintegrating Tablet often experience side effects that include a feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Although, not every person faces the side effects of Ondafresh-MD 4 mg Disintegrating Tablet , and even some of the unpleasant effects of Ondafresh-MD 4 mg Disintegrating Tablet do not require medical attention.

The use of Ondafresh-MD 4 mg Disintegrating Tablet is restricted in persons who are allergic to any of the ingredients present in this medicine. Tell your doctor if you are facing liver, kidney, or heart disorders. Ondafresh-MD 4 mg Disintegrating Tablet should be used during pregnancy or breastfeeding after consulting a doctor. Ondafresh-MD 4 mg Disintegrating Tablet contains lactose so tell your doctor if you have an intolerance to some sugars.

Uses of Ondafresh-MD 4 mg Disintegrating Tablet

Ondafresh-MD 4 mg Disintegrating Tablet is used in the prevention of Nausea and Vomiting. The detailed uses of Ondafresh-MD 4 mg Disintegrating Tablet are as follows:
•Chemotherapy-Induced Nausea: Ondafresh-MD 4 mg Disintegrating Tablet is frequently prescribed to alleviate nausea and vomiting caused by chemotherapy treatments.
•Radiation Therapy Support: Ondafresh-MD 4 mg Disintegrating Tablet can help manage nausea and vomiting experienced by patients undergoing radiation therapy, improving treatment tolerance.
•Postoperative Nausea Relief: Many patients experience nausea after surgical procedures, and Ondafresh-MD 4 mg Disintegrating Tablet is effective in controlling and reducing these symptoms.

Directions for Use

Tablet: It can be taken with or without a meal as advised by the doctor. Swallow the tablet as a whole with a glass of water. Do not break, crush or chew it. Oral disintegrating tablet/Mouth dissolving tablet (tablet MD): Check the label for directions before use. Do not handle the tablet with wet hands. Place the tablet in the mouth and allow it to dissolve. Do not swallow it as a whole.

Medicinal Benefits

Ondafresh-MD 4 mg Disintegrating Tablet belongs to a group of medications called anti-emetics used to prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness in adults and children above 4 years of age. When serotonin level increases in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain responsible for controlling nausea and vomiting. Ondafresh-MD 4 mg Disintegrating Tablet acts by inhibiting the release of this serotonin, thereby preventing nausea and vomiting. 

How Ondafresh-MD 4 mg Disintegrating Tablet Works

Ondafresh-MD 4 mg Disintegrating Tablet contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Ondafresh-MD 4 mg Disintegrating Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ondafresh-MD 4 mg Disintegrating Tablet

  • Sensations of flushing
  • Constipation
  • Headache
  • Confusion
  • Dizziness
  • Fast heartbeat
  • Fever
  • Headache
  • Shortness of breath
  • Weakness

What if I have taken an overdose of Ondafresh-MD 4 mg Disintegrating Tablet

Do not take more than the prescribed dose of Ondafresh-MD 4 mg Disintegrating Tablet as it may cause overdose. The symptoms of overdose include sudden loss of vision for a short time, irregular heartbeat, constipation, fainting, dizziness or lightheadedness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Tell your doctor if you are dealing with an uneven heart, liver problems, or any other problem. Tell your doctor if you are taking medicine for epilepsy, cancer medicines, and abnormal heartbeats. Ondafresh-MD 4 mg Disintegrating Tablet may affect a person's ability to drive. Therefore, should avoid driving or operating any machine. People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Ondafresh-MD 4 mg Disintegrating Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Ondafresh-MD 4 mg Disintegrating Tablet daily. Ondafresh-MD 4 mg Disintegrating Tablet should be used during pregnancy or breastfeeding after consultation with a doctor. Taking Ondafresh-MD 4 mg Disintegrating Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OndansetronFluoxetine
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Ondafresh-MD 4 mg Disintegrating Tablet:
Taking Ondafresh-MD 4 mg Disintegrating Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ondafresh-MD 4 mg Disintegrating Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronFluoxetine
Severe
How does the drug interact with Ondafresh-MD 4 mg Disintegrating Tablet:
Co-administration of Ondafresh-MD 4 mg Disintegrating Tablet with Fluoxetine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Ondafresh-MD 4 mg Disintegrating Tablet along with fluoxetine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
OndansetronFentanyl
Severe
How does the drug interact with Ondafresh-MD 4 mg Disintegrating Tablet:
Taking fentanyl with Ondafresh-MD 4 mg Disintegrating Tablet may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking fentanyl with Ondafresh-MD 4 mg Disintegrating Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain or stiffness, stomach cramps, vomiting, or diarrhoea, consult a doctor. Do not discontinue any medications without consulting your doctor.
OndansetronSumatriptan
Severe
How does the drug interact with Ondafresh-MD 4 mg Disintegrating Tablet:
Using Ondafresh-MD 4 mg Disintegrating Tablet together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of Ondafresh-MD 4 mg Disintegrating Tablet along with sumatriptan can lead to an interaction, it should be taken only if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronFluvoxamine
Severe
How does the drug interact with Ondafresh-MD 4 mg Disintegrating Tablet:
When Ondafresh-MD 4 mg Disintegrating Tablet is taken with fluvoxamine, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondafresh-MD 4 mg Disintegrating Tablet along with fluvoxamine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not discontinue any medications without a doctor's advice.
OndansetronAlfuzosin
Severe
How does the drug interact with Ondafresh-MD 4 mg Disintegrating Tablet:
Taking Ondafresh-MD 4 mg Disintegrating Tablet along with alfuzosin can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Ondafresh-MD 4 mg Disintegrating Tablet along with alfuzosin can lead to interaction, they can be taken if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OndansetronMirtazapine
Severe
How does the drug interact with Ondafresh-MD 4 mg Disintegrating Tablet:
Using Ondafresh-MD 4 mg Disintegrating Tablet with mirtazapine might raise serotonin hormone levels in the body, affects the brain and nerve cells.

How to manage the interaction:
Co-administration of Ondafresh-MD 4 mg Disintegrating Tablet along with mirtazapine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not discontinue any medications without a doctor's advice.
OndansetronRibociclib
Severe
How does the drug interact with Ondafresh-MD 4 mg Disintegrating Tablet:
Taking Ondafresh-MD 4 mg Disintegrating Tablet with ribociclib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondafresh-MD 4 mg Disintegrating Tablet along with ribociclib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronBedaquiline
Severe
How does the drug interact with Ondafresh-MD 4 mg Disintegrating Tablet:
Taking Ondafresh-MD 4 mg Disintegrating Tablet with bedaquiline increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondafresh-MD 4 mg Disintegrating Tablet along with bedaquiline can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
OndansetronLinezolid
Severe
How does the drug interact with Ondafresh-MD 4 mg Disintegrating Tablet:
When Ondafresh-MD 4 mg Disintegrating Tablet is taken with linezolid it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondafresh-MD 4 mg Disintegrating Tablet along with linezolid can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting. 

  • One should avoid taking greasy or oily foods as this food triggers nausea and vomit.

  • Eat cool foods instead of hot and spicy foods.

  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid make up which has got lost due to vomiting. 

 

Habit Forming

No

Therapeutic Class

ANTIEMETICS

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Alcohol

Unsafe

One should avoid consuming alcohol while taking Ondafresh-MD 4 mg Disintegrating Tablet as this medicine can interact with alcohol and may worsen the side effects.

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Pregnancy

Safe if prescribed

Ondafresh-MD 4 mg Disintegrating Tablet could be used during pregnancy after consulting a doctor.

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Breast Feeding

Safe if prescribed

Ondafresh-MD 4 mg Disintegrating Tablet could be used during breastfeeding after consulting a doctor.

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Driving

Caution

Ondafresh-MD 4 mg Disintegrating Tablet may cause lightheadedness in the body, so a person taking Ondafresh-MD 4 mg Disintegrating Tablet should avoid driving or operating any heavy machinery or tasks that require mental alertness.

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Liver

Safe if prescribed

In persons dealing with liver problems, the use of Ondafresh-MD 4 mg Disintegrating Tablet is allowed if prescribed by the doctor. However, in patients with severe liver problems should take a low dose of Ondafresh-MD 4 mg Disintegrating Tablet as much as possible. Do not take more than 8 mg of Ondafresh-MD 4 mg Disintegrating Tablet per day in case of liver disease.

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Kidney

Safe if prescribed

The use of Ondafresh-MD 4 mg Disintegrating Tablet is safe in patients dealing with kidney disorders. No dose adjustment is required.

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Children

Safe if prescribed

Ondafresh-MD 4 mg Disintegrating Tablet should not be given to the children below 4 years of age. The use of Ondafresh-MD 4 mg Disintegrating Tablet is safe in children above 4 years of age if prescribed by the doctor.

FAQs

Ondafresh-MD 4 mg Disintegrating Tablet is indicated in the treatment of nausea and vomiting.

Ondafresh-MD 4 mg Disintegrating Tablet works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.

Ondafresh-MD 4 mg Disintegrating Tablet may cause changes in the vision, so one should avoid driving or operating any machine that required mental alertness.

People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Ondafresh-MD 4 mg Disintegrating Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Ondafresh-MD 4 mg Disintegrating Tablet daily. Taking Ondafresh-MD 4 mg Disintegrating Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Ondafresh-MD 4 mg Disintegrating Tablet is an anti-sickness medicine that takes about 1-2 hours to show its action.

Ondafresh-MD 4 mg Disintegrating Tablet contains Ondansetron, an antiemetic drug.

Ondafresh-MD 4 mg Disintegrating Tablet is ineffective in preventing nausea associated with motion sickness.

Before taking the Ondafresh-MD 4 mg Disintegrating Tablet , let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Yes, Ondafresh-MD 4 mg Disintegrating Tablet might make you feel sleepy or tired.

Ondafresh-MD 4 mg Disintegrating Tablet usually works quickly, usually within 30 minutes, but it can take up to two hours for the full effect.

Common side effects of Ondafresh-MD 4 mg Disintegrating Tablet may include warmth, constipation, headache, diarrhoea, drowsiness, and tiredness. However, not every person faces these side effects, and even some of the unpleasant effects of Ondafresh-MD 4 mg Disintegrating Tablet do not require medical attention.

Ondafresh-MD 4 mg Disintegrating Tablet was not found to be beneficial in the treatment of seasickness.

Ondafresh-MD 4 mg Disintegrating Tablet works by blocking the action of a chemical in the body (serotonin) that is responsible for causing nausea and vomiting. As a result, Ondafresh-MD 4 mg Disintegrating Tablet prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Yes, you can take Ondafresh-MD 4 mg Disintegrating Tablet half an hour to 1 hour before meals.

If you forget to take a dose of Ondafresh-MD 4 mg Disintegrating Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.

Ondafresh-MD 4 mg Disintegrating Tablet may cause changes in the vision, so one should avoid driving or operating any machine that requires mental alertness.

Suppose you took more than the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Ondafresh-MD 4 mg Disintegrating Tablet may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

No, Ondafresh-MD 4 mg Disintegrating Tablet is not a steroid. Ondafresh-MD 4 mg Disintegrating Tablet belongs to a class of drugs known as anti-emetics.

While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.

Take Ondafresh-MD 4 mg Disintegrating Tablet exactly as prescribed by the doctor. Take it at the same time daily as it will help you to remember taking the medication.

Yes, Ondafresh-MD 4 mg Disintegrating Tablet has also been prescribed during pregnancy to help with symptoms of nausea and vomiting in pregnancy.

Country of origin

India

Manufacturer/Marketer address

1004, Brooklyn Tower, Nr. YMCA Club, S.g.Highway, Ahmedabad, Gujarat 380051
Other Info - OND0151

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