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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Periset MD Tablet is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment or surgery. It contains Ondanestron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. It may cause side effects such as feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition :

ONDANSETRON-4MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Periset MD Tablet belongs to a group of medications called ' anti-emetics' primarily used in the prevention of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit while vomiting is the natural response to the body to forcefully discharge the stomach contents.

Periset MD Tablet contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Periset MD Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Take Periset MD Tablet as prescribed. Your doctor will advise you on how often you take Periset MD Tablet based on your medical condition. A person taking Periset MD Tablet often experience side effects that include a feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Although, not every person faces the side effects of Periset MD Tablet , and even some of the unpleasant effects of Periset MD Tablet do not require medical attention.

The use of Periset MD Tablet is restricted in persons who are allergic to any of the ingredients present in this medicine. Tell your doctor if you are facing liver, kidney, or heart disorders. Periset MD Tablet should be used during pregnancy or breastfeeding after consulting a doctor. Periset MD Tablet contains lactose so tell your doctor if you have an intolerance to some sugars.

Treatment of Nausea, Vomiting.
Tablet: It can be taken with or without a meal as advised by the doctor. Swallow the tablet as a whole with a glass of water. Do not break, crush or chew it. Oral disintegrating tablet/Mouth dissolving tablet (tablet MD): Check the label for directions before use. Do not handle the tablet with wet hands. Place the tablet in the mouth and allow it to dissolve. Do not swallow it as a whole.

Periset MD Tablet belongs to a group of medications called anti-emetics used to prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness in adults and children above 4 years of age. When serotonin level increases in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain responsible for controlling nausea and vomiting. Periset MD Tablet acts by inhibiting the release of this serotonin, thereby preventing nausea and vomiting. 

Periset MD Tablet contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Periset MD Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.
Store in a cool and dry place away from sunlight
  • Sensations of flushing
  • Constipation
  • Headache
  • Confusion
  • Dizziness
  • Fast heartbeat
  • Fever
  • Headache
  • Shortness of breath
  • Weakness
Do not take more than the prescribed dose of Periset MD Tablet as it may cause overdose. The symptoms of overdose include sudden loss of vision for a short time, irregular heartbeat, constipation, fainting, dizziness or lightheadedness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Tell your doctor if you are dealing with an uneven heart, liver problems, or any other problem. Tell your doctor if you are taking medicine for epilepsy, cancer medicines, and abnormal heartbeats. Periset MD Tablet may affect a person's ability to drive. Therefore, should avoid driving or operating any machine. People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Periset MD Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Periset MD Tablet daily. Periset MD Tablet should be used during pregnancy or breastfeeding after consultation with a doctor. Taking Periset MD Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

verifiedApollotooltip
OndansetronZiprasidone
Critical
OndansetronNortriptyline
Severe

Drug-Drug Interactions

OndansetronZiprasidone
Critical
How does the drug interact with Periset MD Tablet 10's:
Taking Periset MD Tablet 10's with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Periset MD Tablet 10's with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronNortriptyline
Severe
How does the drug interact with Periset MD Tablet 10's:
Using Nortriptyline together with Periset MD Tablet 10's can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Periset MD Tablet 10's along with nortriptyline can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, or diarrhea. while taking these medications. Do not discontinue any medications without a doctor's advice.
OndansetronOsimertinib
Severe
How does the drug interact with Periset MD Tablet 10's:
Taking Periset MD Tablet 10's with Osimertinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Periset MD Tablet 10's along with Osimertinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronParoxetine
Severe
How does the drug interact with Periset MD Tablet 10's:
When Periset MD Tablet 10's is taken with paroxetine, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Periset MD Tablet 10's along with paroxetine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medication without consulting a doctor.
OndansetronTranylcypromine
Severe
How does the drug interact with Periset MD Tablet 10's:
When Periset MD Tablet 10's, is taken with tranylcypromine it increases the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
Although taking Periset MD Tablet 10's along with tranylcypromine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronMethadone
Severe
How does the drug interact with Periset MD Tablet 10's:
Taking Periset MD Tablet 10's with methadone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Periset MD Tablet 10's along with methadone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronDisopyramide
Severe
How does the drug interact with Periset MD Tablet 10's:
Taking Periset MD Tablet 10's with disopyramide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Periset MD Tablet 10's along with disopyramide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronLithium
Severe
How does the drug interact with Periset MD Tablet 10's:
Taking Periset MD Tablet 10's with lithium can increase the risk of serotonin syndrome a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Periset MD Tablet 10's along with lithium can result in an interaction but can be taken together if prescribed by a doctor. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools, or fast or rapid heartbeats during therapy, consult a doctor. Do not stop using any medications without talking to a doctor.
OndansetronProtriptyline
Severe
How does the drug interact with Periset MD Tablet 10's:
When Periset MD Tablet 10's is taken with protriptyline, it can increase the risk of serotonin syndrome (Serotonin syndrome is a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Periset MD Tablet 10's along with protriptyline can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not discontinue any medications without a doctor's advice.
OndansetronCeritinib
Severe
How does the drug interact with Periset MD Tablet 10's:
Taking ceritinib together with Periset MD Tablet 10's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Periset MD Tablet 10's along with ceritinib can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting. 

  • One should avoid taking greasy or oily foods as this food triggers nausea and vomit.

  • Eat cool foods instead of hot and spicy foods.

  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid make up which has got lost due to vomiting. 

 

No
ANTIEMETICS

Periset MD Tablet Substitute

Substitutes safety advice
  • Nuavomin 4 mg Tablet

    5.18per tablet
  • Ondem-MD 4 Tablet 10's

    5.18per tablet
  • Emeset-4 Tablet 10's

    5.18per tablet
  • Zofer MD 4 Tablet 10's

    5.13per tablet
  • Ondem 4 Tablet 10's

    5.18per tablet
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Unsafe

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Safe if prescribed

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Safe if prescribed

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Caution

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Safe if prescribed

bannner image

Safe if prescribed

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Safe if prescribed

FAQs

Periset MD Tablet is indicated in the treatment of nausea and vomiting.
Periset MD Tablet works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.
Periset MD Tablet may cause changes in the vision, so one should avoid driving or operating any machine that required mental alertness.
People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Periset MD Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Periset MD Tablet daily. Taking Periset MD Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.
Periset MD Tablet is an anti-sickness medicine that takes about 1-2 hours to show its action.
Periset MD Tablet contains Ondansetron, an antiemetic drug.
Periset MD Tablet is ineffective in preventing nausea associated with motion sickness.
Before taking the Periset MD Tablet , let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Yes, Periset MD Tablet might make you feel sleepy or tired.
Periset MD Tablet usually works quickly, usually within 30 minutes, but it can take up to two hours for the full effect.
Common side effects of Periset MD Tablet may include warmth, constipation, headache, diarrhoea, drowsiness, and tiredness. However, not every person faces these side effects, and even some of the unpleasant effects of Periset MD Tablet do not require medical attention.
Periset MD Tablet was not found to be beneficial in the treatment of seasickness.
Periset MD Tablet works by blocking the action of a chemical in the body (serotonin) that is responsible for causing nausea and vomiting. As a result, Periset MD Tablet prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.
Yes, you can take Periset MD Tablet half an hour to 1 hour before meals.
If you forget to take a dose of Periset MD Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.
Periset MD Tablet may cause changes in the vision, so one should avoid driving or operating any machine that requires mental alertness.
Suppose you took more than the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Periset MD Tablet may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.
No, Periset MD Tablet is not a steroid. Periset MD Tablet belongs to a class of drugs known as anti-emetics.
While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.
Take Periset MD Tablet exactly as prescribed by the doctor. Take it at the same time daily as it will help you to remember taking the medication.
Yes, Periset MD Tablet has also been prescribed during pregnancy to help with symptoms of nausea and vomiting in pregnancy.
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