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Nextril 50 Tablet 10's

Nextril 50 Tablet 10's

Not for online sale
Prescription drug
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Consult Doctor

Composition

TOFISOPAM-50MG

Manufacturer/Marketer

Torrent Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Nextril 50 Tablet

Nextril 50 Tablet is used to treat depression and associated anxiety with depression. Depression is a mood disorder that mainly affects a person's daily life. It leads to feelings of sadness, anger, or loss that affect the quality of life.  An anxiety disorder is a mental condition characterized by feelings of excessive fear or worry that affect an individual's daily activities. 

Nextril 50 Tablet contains benzodiazepine named Tofisopam, primarily used to treat depression. It works by increasing the action of a chemical messenger in the brain known as GABA (gamma-amino-butyric-acid), which suppresses the excessive and abnormal activity of nerve cells in the brain. As a result, this reduces tension, creates a feeling of well-being, relieves anxiety, helps you sleep better, and increases your energy levels so that you can perform daily activities. It also, in turn, improves the quality of life.

Take Nextril 50 Tablet as prescribed by your doctor. You are advised to take Nextril 50 Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience loss of appetite, dryness in the mouth, nausea, insomnia (difficulty in sleeping), and headache. Most of these side effects of Nextril 50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Nextril 50 Tablet has a very high potential for habit-forming, so take it only in the dose and duration prescribed by your doctor. Do not abruptly stop taking Nextril 50 Tablet as it might lead to nausea, aggressive behavior, anxiety, confusion. Inform your doctor if you feel better, and accordingly, the dose will be adjusted. It is known to cause drowsiness, so do not operate any machinery or drive a car, as it requires mental focus. Please inform your doctor if you are pregnant, planning to get pregnant, or breastfeeding as it a pregnancy category D drug. Also, alcohol consumption should be avoided as it might increase the drowsiness effect and cause excessive sleepiness.

Uses of Nextril 50 Tablet

Treatment of anxiety and depression.

Medicinal Benefits

Nextril 50 Tablet contains an 'anti-depression medication', Tofisopam, primarily used to treat depression and associated anxiety with depression. It works by increasing the action of a chemical messenger known as GABA (gamma-amino-butyric-acid), which suppresses the excessive and abnormal activity of nerve cells in the brain. As a result, this reduces tension, creates a feeling of well-being, relieves anxiety, helps you sleep better, and increases your energy levels so that you can perform daily activities. It also, in turn, improves the quality of life.

Directions for Use

Swallow Nextril 50 Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nextril 50 Tablet

  • Loss of appetite
  • Dryness in mouth
  • Nausea
  • Insomnia (difficulty in sleeping)
  • Headache
  • Constipation
  • Stomach discomfort
  • Drowsiness

Drug Warnings

Do not take Nextril 50 Tablet if you are allergic to benzodiazepines or any ingredient of Nextril 50 Tablet . Nextril 50 Tablet has a very high potential for habit-forming, so take it only in dose and duration prescribed by your doctor. Do not abruptly stop taking Nextril 50 Tablet as it might lead to nausea, aggressive behavior, anxiety, confusion. Inform your doctor if you feel better, and accordingly, the dose will be adjusted. It is known to cause drowsiness, so do not operate any machinery or drive a car as it requires mental focus. Please inform your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Also, alcohol consumption should be avoided as it might increase the drowsiness effect and cause excessive sleepiness.

Drug Interactions

Drug-Drug Interaction: This medicine may have interactions with other benzodiazepines (bromazepam, diazepam, lorazepam), antianxiety or antiepileptic medicines (like carbamazepine, fluvoxamine, phenobarbital, phenytoin, primidone), antifungal drugs (ketoconazole, itraconazole, voriconazole, fluconazole), acidity medicine (aluminum hydroxide, calcium carbonate, omeprazole, cimetidine), immuno-suppressant (cyclosporine), heart medicines (digoxin, digitoxin, isoniazid).

Drug-Food Interaction: Nextril 50 Tablet may interact with a multivitamin, multi-mineral, or other herbal supplements. So, if you are using any of the OTC items, please tell your doctor. Also, avoid consumption of alcohol and caffeine contains beverages like tea, coffee.

Drug-Disease Interaction: Nextril 50 Tablet is known to interact in patients with glaucoma (increased eye pressure), epilepsy, respiratory problems (asthma), liver or kidney problems, social phobia.

Drug-Drug Interactions Checker List

  • DIAZEPAM
  • LORAZEPAM
  • CARBAMAZEPINE
  • FLUVOXAMINE
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • FLUCONAZOLE
  • ALUMINIUM HYDROXIDE
  • CALCIUM CARBONATE
  • OMEPRAZOLE
  • CIMETIDINE
  • CYCLOSPORINE
  • DIGOXIN
  • ISONIAZID

Habit Forming

Yes

Diet & Lifestyle Advise

  • Do regular exercise, which can help lower anxiety by releasing endorphins and improving your sleep and self-image.
  • Find humour in your daily life. Try to watch light-hearted shows to help relieve stress.
  • You can try increasing your mindfulness by including yoga, meditation, mindfulness-based cognitive therapy, and mindfulness-based stress reduction.
  • Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • Herbs like turmeric, ginger, and chamomile have anti-inflammatory properties. Including these in meals can reduce inflammation caused by anxiety disorders.
  • Reduce your alcohol, caffeine, added sugar, high salt, and high fat intake. Especially trans-fat may help also help reduce inflammation.
  • Antioxidants, such as ashwagandha, omega-3 fatty acids, green tea, and lemon balm, can be included in your daily diet.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Special Advise

  • Nextril 50 Tablet causes drowsiness. Avoid doing activities that require your complete focus and attention, like driving when on this drug.
  • An abrupt stoppage of Nextril 50 Tablet can lead to significant withdrawal symptoms. Always discuss decreasing the dosage with your doctor before completely stopping its usage.
  • Avoid consuming alcohol while on this medication, as it can lead to dangerous side effects.
  • Nextril 50 Tablet is unsafe for usage if you're pregnant or are planning to get pregnant. Discuss with your doctor about changing/replacing the medicine with safer alternatives in such situations.
  • To avoid getting addicted to Nextril 50 Tablet , take it only in prescribed quantities and only as directed by your doctor. Do not self-medicate.

Disease/Condition Glossary

Depression: Depression is considered a serious mental disorder that can lead to worsening of the condition if not treated. It is a mood disorder that mainly affects a person's daily life. It leads to feelings of sadness, anger, or loss that affect the quality of life. It can lead to low productivity at work.

Anxiety: High levels of anxiety can cause panic attacks, with intense feelings of nervousness, fear, and sudden onset of sweating, hyperventilation, fast heartbeat, and flushing of the skin. Anxiety disorders are different from feelings of anxiety and feeling nervous, which involve excessive anxiety, fear, or worry. Fear can arise due to anxiety and emotional response to an immediate threat related to more staying to fight or leaving to escape danger. Fear before getting ready for the surgery is also a part of the short-term anxiety. Anxiety disorders can affect an individual’s job performance, school work, and personal relationships.

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Alcohol

Caution

You are recommended not to consume alcohol along with Nextril 50 Tablet to avoid unpleasant side-effects like drowsiness, dizziness, or sleepiness. It may also lead to a life-threatening condition like coma if taken with excessive alcohol.

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Pregnancy

Unsafe

Nextril 50 Tablet is a Category D risk pregnancy drug that is considered unsafe for pregnant women. Nextril 50 Tablet can have some harmful effects on the baby (fetus), so your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Unsafe

Nextril 50 Tablet passes into the breast milk and may cause some degree of sedation in the baby. So, keep your doctor informed if you're planning to breastfeed while on this medication.

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Driving

Unsafe

Nextril 50 Tablet usually causes dizziness, drowsiness, and visual disturbances, which may affect their ability to drive or operate machinery. So, do not drive or operate heavy machinery if you feel sleepy or dizzy after taking Nextril 50 Tablet . Tell your doctor if you get these types of side effects.

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Liver

Caution

Nextril 50 Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Nextril 50 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

It is unknown whether Nextril 50 Tablet is safe or effective in treating conditions like panic disorder in children younger than 18 years old. So, your doctor will decide whether Nextril 50 Tablet can be given to children less than 18 years of age or not.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - NEX0194

Author Details

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FAQs

Nextril 50 Tablet is used to treat depression and associated anxiety with depression.
Nextril 50 Tablet contains Tofisopam (benzodiazepine), which is used to treat anxiety. Tofisopam works by increasing the action of a chemical messenger GABA, which suppresses the excessive and abnormal activity of nerve cells in the brain.
Do not abruptly stop taking Nextril 50 Tablet as it might lead to nausea, aggressive behavior, anxiety, confusion. Inform your doctor if you feel better, and accordingly, the dose will be adjusted.
Nextril 50 Tablet is generally not recommended for elderly patients as it is known to reduce muscle tone and increase the risk of falls. So, if a doctor prescribes it, only then take it.
Yes, Nextril 50 Tablet may cause mental or physical dependence if used for a prolonged time. Therefore, take Nextril 50 Tablet only in dose and duration as advised by your doctor.
If you have taken a double dose or overdose of Nextril 50 Tablet , you need immediate medical help either by calling a doctor or going to the nearest hospital or clinic.
Caffeine is a stimulant that may reduce the calming effects of tofisopam. So, it is advisable to avoid the intake of caffeinated beverages like coffee, tea, and cola, or chocolate that contain caffeine.

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