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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Nefdyl Syrup is a combination medicine which belongs to the class of expectorants. It is used in the treatment of cough. This medicine works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Common side effects include dry mouth, throat, or nose, drowsiness, blurred vision, constipation, dizziness, restlessness or excitation.
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Manufacturer/Marketer :

Noel Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Nefdyl Syrup

Nefdyl Syrup belongs to a group of medicines called expectorants and cough products used to provide relief from cough. Additionally, Nefdyl Syrup may also help in providing relief from allergy and nasal congestion due to cold. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways, thereby preventing respiratory infection. 
 
Nefdyl Syrup contains Ammonium chloride, Diphenhydramine hydrochloride, and Sodium citrate. Ammonium chloride helps remove phlegm/mucus from the airways by decreasing its stickiness. Diphenhydramine hydrochloride works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. Sodium citrate helps in reducing congestion, thereby making it easier to cough out through the mouth. Together, Nefdyl Syrup provides relief from cough. 
 
You are advised to take Nefdyl Syrup for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, stomach upset, dizziness, tiredness, and dry mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant or breastfeeding. Nefdyl Syrup may cause dizziness, so drive only if you are alert. Nefdyl Syrup should be given to children only if prescribed by the doctor. Avoid consuming alcohol with Nefdyl Syrup as it could lead to increased dizziness. Inform your doctor about all the prescription, non-prescription and herbal medicines you are taking to rule out any side effects/interactions.

Uses of Nefdyl Syrup

Treatment of Cough

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Nefdyl Syrup is a combination of three drugs, namely: Ammonium chloride and Diphenhydramine hydrochloride, and Sodium citrate. Nefdyl Syrup is used to provide relief from a cough accompanied by cold symptoms such as sore throat, runny nose, watery eyes, and sneezing. Additionally, Nefdyl Syrup helps in providing relief from allergy. Ammonium chloride is an expectorant that helps remove phlegm/mucus from the airways by decreasing its stickiness. Diphenhydramine hydrochloride is an antihistamine that works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. Sodium citrate is a mucolytic agent that helps in loosening the congestion, thereby making it easier to cough out through the mouth. Together, Nefdyl Syrup provides relief from cough.

How Nefdyl Syrup Works

Nefdyl Syrup contains Ammonium chloride, Diphenhydramine hydrochloride, and Sodium citrate. Ammonium chloride helps remove phlegm/mucus from the airways by decreasing its stickiness. Diphenhydramine hydrochloride works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. Sodium citrate helps in reducing congestion, thereby making it easier to cough out through the mouth. Together, Nefdyl Syrup provides relief from cough.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nefdyl Syrup

  • Stomach upset
  • Dizziness
  • Sleepiness
  • Dry mouth
  • Headache

What if I have taken an overdose of Nefdyl Syrup

Avoid exceeding the recommended dose as it might cause an overdose. Seek medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Nefdyl Syrup if you are allergic to any of its contents. Inform your doctor if you have asthma, prostate problems, narrow-angle glaucoma, stomach or bowel ulcers, glucose-galactose malabsorption, sucrase-isomaltase deficiency, fructose intolerance, kidney or liver problems; if you are taking antidepressants or anti-Parkinson drugs or have taken them in the last 14days. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Nefdyl Syrup may cause dizziness, so drive only if you are alert. Avoid consuming alcohol with Nefdyl Syrup as it could lead to increased dizziness.

Drug-Drug Interactions

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DiphenhydramineEliglustat
Critical
DiphenhydraminePotassium chloride
Critical

Drug-Drug Interactions

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DiphenhydramineEliglustat
Critical
How does the drug interact with Nefdyl Syrup 100 ml:
When Nefdyl Syrup 100 ml is taken with Eliglustat, it can cause a decrease in metabolism.

How to manage the interaction:
Taking Nefdyl Syrup 100 ml with Eliglustat is not recommended, please consult your doctor before taking it. It can be taken if prescribed by your doctor. Do not stop taking any medication without consulting your doctor.
DiphenhydraminePotassium chloride
Critical
How does the drug interact with Nefdyl Syrup 100 ml:
Taking Nefdyl Syrup 100 ml with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Nefdyl Syrup 100 ml with Potassium chloride is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, contact your doctor. Do not stop taking any medication without consulting your doctor.
DiphenhydramineSodium oxybate
Critical
How does the drug interact with Nefdyl Syrup 100 ml:
Taking Nefdyl Syrup 100 ml with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Nefdyl Syrup 100 ml with Sodium oxybate is not recommended, but it can be taken if prescribed by a doctor. However contact your doctor if you experience shortness of breath, increased sweating, palpitations, or confusion. Do not stop using any medications without consulting a doctor.
DiphenhydraminePotassium citrate
Critical
How does the drug interact with Nefdyl Syrup 100 ml:
Taking Nefdyl Syrup 100 ml and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Nefdyl Syrup 100 ml with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DiphenhydramineThioridazine
Critical
How does the drug interact with Nefdyl Syrup 100 ml:
When Thioridazine is taken with Nefdyl Syrup 100 ml, it can slow down the way Nefdyl Syrup 100 ml is broken down in the body.

How to manage the interaction:
Taking Nefdyl Syrup 100 ml with Thioridazine is not recommended, please consult your doctor before taking it. It can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
DiphenhydramineTopiramate
Severe
How does the drug interact with Nefdyl Syrup 100 ml:
Topiramate can induce elevated body temperature and decreased sweating, which can be exacerbated when combined with drugs that have similar effects, such as Nefdyl Syrup 100 ml.

How to manage the interaction:
Although taking Nefdyl Syrup 100 ml with Topiramate can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is essential to stay hydrated by drinking enough fluids, especially in hot weather and when doing physical activity. Contact your doctor immediately if you notice decreased sweating, fever, dizziness, drowsy, or lightheadedness. Do not discontinue using any medications without consulting a doctor.
DiphenhydramineTamoxifen
Severe
How does the drug interact with Nefdyl Syrup 100 ml:
Nefdyl Syrup 100 ml reduces the blood levels and effectiveness of tamoxifen.

How to manage the interaction:
Although taking Nefdyl Syrup 100 ml with Tamoxifen can possibly reduce the effectiveness of Tamoxifen, they can be taken together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
DiphenhydramineBrexpiprazole
Severe
How does the drug interact with Nefdyl Syrup 100 ml:
Nefdyl Syrup 100 ml increases the blood levels of Brexpiprazole. This increases the risk of Side effects.

How to manage the interaction:
Taking Nefdyl Syrup 100 ml with Brexpiprazole together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - feeling tired, unusual muscle movements, muscle spasms, shaking or jerking in your arms and legs, feeling dizzy or lightheaded, or fainting - contact your doctor right away. Do not stop using any medications without talking to a doctor.
DiphenhydramineEsketamine
Severe
How does the drug interact with Nefdyl Syrup 100 ml:
Taking Nefdyl Syrup 100 ml with Esketamine can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Nefdyl Syrup 100 ml with Esketamine can result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, confusion, or difficulty concentrating. Do not discontinue any medications without consulting a doctor.
DiphenhydramineKetamine
Severe
How does the drug interact with Nefdyl Syrup 100 ml:
Taking ketamine with Nefdyl Syrup 100 ml can increase the risk of side effects.

How to manage the interaction:
Although taking Nefdyl Syrup 100 ml with Ketamine can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience severe dizziness, confusion, drowsiness, confusion, difficulty concentrating, or excessive sleepiness consult your doctor immediately. Do not discontinue using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Gargle with salt water for relief from sore throat.
  • Avoid smoking and consumption of alcohol.
  • Avoid dairy products such as milk, as it may increase mucus production.
  • Avoid processed or refined foods. Replace baked foods, fried foods, white bread, white pasta, french fries, sugary desserts and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid a dry throat. It also helps loosen mucus.
  • Avoid citrus fruits as they may worsen the cough.
  • Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Habit Forming

No

Therapeutic Class

EXPECTORANT AND COUGH PRODUCTS

Nefdyl Syrup Substitute

Substitutes safety advice
  • COF-RYL Cough Syrup 100 ml

    0.90per tablet
  • Apihist Cough Expectorant 4.5 Litre

    149.85per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Nefdyl Syrup as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid taking Nefdyl Syrup if you are breastfeeding. Consult your doctor if you have any concerns.

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Driving

Caution

Nefdyl Syrup may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Nefdyl Syrup should be given to children only if prescribed by the doctor.

FAQs

Nefdyl Syrup belongs to a group of medicines called expectorants and cough products used to provide relief from cough. Additionally, Nefdyl Syrup may also help in providing relief from allergy and nasal congestion due to cold.
Nefdyl Syrup contains Ammonium chloride, Diphenhydramine hydrochloride, and Sodium citrate. Ammonium chloride helps remove phlegm/mucus from the airways by decreasing its stickiness. Diphenhydramine hydrochloride works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. Sodium citrate helps loosen the congestion, thereby making it easier to cough out through the mouth. Together, Nefdyl Syrup provides relief from cough.
Do not stop taking Nefdyl Syrup on your own as it may worsen your cough or cause recurring symptoms. Therefore, take Nefdyl Syrup for as long as your doctor has prescribed it. If you experience any difficulty while taking Nefdyl Syrup , please consult your doctor.
Nefdyl Syrup contains diphenhydramine hydrochloride, an antihistamine that helps in treating allergies. Therefore, consult a doctor before taking any other anti-histamine medicines along with Nefdyl Syrup .
Dry mouth could be a side-effect of Nefdyl Syrup . Limiting caffeine intake, avoiding smoking, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Nefdyl Syrup should not be taken for longer durations unless prescribed by the doctor. If your condition does not improve despite taking Nefdyl Syrup for a week, consult your doctor, he/she may prescribe an alternate medicine.

Country of origin

INDIA

Manufacturer/Marketer address

Khasra No. 66/3, & 67/2, Juddi Kalan, Baddi-173205, Distt. Solan (H.P.)
Other Info - NEF0003

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