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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:37 PM IST
COF-RYL Cough Syrup is a combination medicine which belongs to the class of expectorants. It is used in the treatment of cough. This medicine works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Common side effects include dry mouth, throat, or nose, drowsiness, blurred vision, constipation, dizziness, restlessness or excitation.
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in last 30 days
Prescription drug

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Prescription drug
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Manufacturer/Marketer

Cipla Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About COF-RYL Cough Syrup

COF-RYL Cough Syrup belongs to a group of medicines called expectorants and cough products used to provide relief from cough. Additionally, COF-RYL Cough Syrup may also help in providing relief from allergy and nasal congestion due to cold. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways, thereby preventing respiratory infection. 
 
COF-RYL Cough Syrup contains Ammonium chloride, Diphenhydramine hydrochloride, and Sodium citrate. Ammonium chloride helps remove phlegm/mucus from the airways by decreasing its stickiness. Diphenhydramine hydrochloride works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. Sodium citrate helps in reducing congestion, thereby making it easier to cough out through the mouth. Together, COF-RYL Cough Syrup provides relief from cough. 
 
You are advised to take COF-RYL Cough Syrup for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, stomach upset, dizziness, tiredness, and dry mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant or breastfeeding. COF-RYL Cough Syrup may cause dizziness, so drive only if you are alert. COF-RYL Cough Syrup should be given to children only if prescribed by the doctor. Avoid consuming alcohol with COF-RYL Cough Syrup as it could lead to increased dizziness. Inform your doctor about all the prescription, non-prescription and herbal medicines you are taking to rule out any side effects/interactions.

Uses of COF-RYL Cough Syrup

Treatment of Cough

Medicinal Benefits

COF-RYL Cough Syrup is a combination of three drugs, namely: Ammonium chloride and Diphenhydramine hydrochloride, and Sodium citrate. COF-RYL Cough Syrup is used to provide relief from a cough accompanied by cold symptoms such as sore throat, runny nose, watery eyes, and sneezing. Additionally, COF-RYL Cough Syrup helps in providing relief from allergy. Ammonium chloride is an expectorant that helps remove phlegm/mucus from the airways by decreasing its stickiness. Diphenhydramine hydrochloride is an antihistamine that works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. Sodium citrate is a mucolytic agent that helps in loosening the congestion, thereby making it easier to cough out through the mouth. Together, COF-RYL Cough Syrup provides relief from cough.

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of COF-RYL Cough Syrup

  • Stomach upset
  • Dizziness
  • Sleepiness
  • Dry mouth
  • Headache

Drug Warnings

Do not take COF-RYL Cough Syrup if you are allergic to any of its contents. Inform your doctor if you have asthma, prostate problems, narrow-angle glaucoma, stomach or bowel ulcers, glucose-galactose malabsorption, sucrase-isomaltase deficiency, fructose intolerance, kidney or liver problems; if you are taking antidepressants or anti-Parkinson drugs or have taken them in the last 14days. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. COF-RYL Cough Syrup may cause dizziness, so drive only if you are alert. Avoid consuming alcohol with COF-RYL Cough Syrup as it could lead to increased dizziness.

Drug Interactions

Drug-Drug Interaction: COF-RYL Cough Syrup may interact with an antidepressant (isocarboxazid, phenelzine, selegiline, tranylcypromine), anti-Parkinson agent (rasagiline).

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: Inform your doctor if you have asthma, prostate problems, narrow-angle glaucoma, stomach or bowel ulcers, glucose-galactose malabsorption, sucrase-isomaltase deficiency, fructose intolerance, kidney or liver problems.

Drug-Drug Interactions Checker List

  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • TRANYLCYPROMINE
  • RASAGILINE

Habit Forming

No

Diet & Lifestyle Advise

  • Gargle with salt water for relief from sore throat.
  • Avoid smoking and consumption of alcohol.
  • Avoid dairy products such as milk, as it may increase mucus production.
  • Avoid processed or refined foods. Replace baked foods, fried foods, white bread, white pasta, french fries, sugary desserts and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid a dry throat. It also helps loosen mucus.
  • Avoid citrus fruits as they may worsen the cough.
  • Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Disease/Condition Glossary

Cough: Coughing is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. Cough can be dry or productive. A productive cough (wet cough) develops sputum (phlegm or mucus) from the lungs. A dry cough does not produce sputum. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking COF-RYL Cough Syrup as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid taking COF-RYL Cough Syrup if you are breastfeeding. Consult your doctor if you have any concerns.

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Driving

Caution

COF-RYL Cough Syrup may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

COF-RYL Cough Syrup should be given to children only if prescribed by the doctor.

Country of origin

India

Manufacturer/Marketer address

52, Industrial Area Phase-1, Chandigarh.
Other Info - COF0006

Author Details

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FAQs

COF-RYL Cough Syrup belongs to a group of medicines called expectorants and cough products used to provide relief from cough. Additionally, COF-RYL Cough Syrup may also help in providing relief from allergy and nasal congestion due to cold.
COF-RYL Cough Syrup contains Ammonium chloride, Diphenhydramine hydrochloride, and Sodium citrate. Ammonium chloride helps remove phlegm/mucus from the airways by decreasing its stickiness. Diphenhydramine hydrochloride works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. Sodium citrate helps loosen the congestion, thereby making it easier to cough out through the mouth. Together, COF-RYL Cough Syrup provides relief from cough.
Do not stop taking COF-RYL Cough Syrup on your own as it may worsen your cough or cause recurring symptoms. Therefore, take COF-RYL Cough Syrup for as long as your doctor has prescribed it. If you experience any difficulty while taking COF-RYL Cough Syrup , please consult your doctor.
COF-RYL Cough Syrup contains diphenhydramine hydrochloride, an antihistamine that helps in treating allergies. Therefore, consult a doctor before taking any other anti-histamine medicines along with COF-RYL Cough Syrup .
Dry mouth could be a side-effect of COF-RYL Cough Syrup . Limiting caffeine intake, avoiding smoking, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
COF-RYL Cough Syrup should not be taken for longer durations unless prescribed by the doctor. If your condition does not improve despite taking COF-RYL Cough Syrup for a week, consult your doctor, he/she may prescribe an alternate medicine.

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