apollo
0
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:47 PM IST
Nefadryl Syrup is used to treat cough. It works by increasing the volume of fluid in the airways, blocking the action of histamine, and facilitating the removal of phlegm. In some cases, this medicine may cause side effects such as drowsiness, dizziness, dry mouth, nervousness, stomach pain, diarrhoea, or constipation. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
Read more
Prescription drug

Whats That

tooltip
Consult Doctor

About Nefadryl Syrup

Nefadryl Syrup belongs to a class of medications called ‘expectorants’ used to treat cough. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways. 

Nefadryl Syrup is a combination of four drugs, namely: Ammonium chloride (expectorants), Diphenhydramine (antihistamine), Sodium citrate (mucolytic), and menthol (cooling agent). Ammonium chloride belongs to the class of expectorants that works by increasing the volume of fluid in the airways, reduce the stickiness of mucus, and helps to remove it from airways. Diphenhydramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Sodium citrate is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby, it helps to cough out easily. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation.

Take Nefadryl Syrup as prescribed by your doctor. You are advised to take Nefadryl Syrup for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience drowsiness, dizziness, dry mouth, nervousness, stomach pain, diarrhea, or constipation. Most of these side effects of Nefadryl Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Nefadryl Syrup or any other medicines, please tell your doctor. Nefadryl Syrup is not recommended for children below 2 years of age unless advised by a doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Nefadryl Syrup. Nefadryl Syrup should be used with caution in elderly patients due to the increased risk of side effects. Drive only if you are alert as Nefadryl Syrup may cause dizziness. You are recommended to avoid alcohol consumption with Nefadryl Syrup as it may increase drowsiness or dizziness.

Uses of Nefadryl Syrup

Treatment of Cough

Medicinal Benefits

Nefadryl Syrup contains Ammonium chloride, Diphenhydramine, Sodium citrate, and menthol used to treat cough. Ammonium chloride is an expectorant that increases the volume of fluid in the airways, reduces the stickiness of mucus, and helps to remove it from the airways. Diphenhydramine is an antihistamine (anti-allergic drug) that blocks the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Sodium citrate is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby, it helps to cough out easily. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation.

Side Effects of Nefadryl Syrup

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Nervousness
  • Stomach pain
  • Diarrhoea
  • Constipation

Directions for Use

Take Nefadryl Syrup with or without food as advised by your doctor. Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Nefadryl Syrup or any other medicines, please tell your doctor. Nefadryl Syrup is not recommended for children below 2 years of age unless advised by a doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Nefadryl Syrup. Nefadryl Syrup should be used with caution in elderly patients due to the increased risk of side effects. Avoid using Nefadryl Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. If you have asthma, inform your doctor before taking Nefadryl Syrup. Drive only if you are alert as Nefadryl Syrup may cause dizziness. You are recommended to avoid alcohol consumption with Nefadryl Syrup as it may increase drowsiness or dizziness. Drink plenty of fluids while taking Nefadryl Syrup to loosen mucus.

Therapeutic Class

EXPECTORANT AND COUGH PRODUCTS

Diet & Lifestyle Advise

  • Avoid dairy products such as milk as they may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead, replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Habit Forming

No

How Nefadryl Syrup Works

Nefadryl Syrup is a combination of four drugs, namely: Ammonium chloride (expectorants), Diphenhydramine (antihistamine), Sodium citrate (mucolytic), and menthol (cooling agent). Ammonium chloride belongs to the class of expectorants that works by increasing the volume of fluid in the airways, reduce the stickiness of mucus, and helps to remove it from airways. Diphenhydramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Sodium citrate is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby, it helps to cough out easily. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation.

What if I have taken an overdose of Nefadryl Syrup

Take Nefadryl Syrup only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.
bannner image

Alcohol

Unsafe

Avoid consumption of alcohol with Nefadryl Syrup as it may increase drowsiness or dizziness.

bannner image

Pregnancy

Caution

Nefadryl Syrup is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

bannner image

Breast Feeding

Caution

Nefadryl Syrup may be excreted in human milk. Therefore, Nefadryl Syrup is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

bannner image

Driving

Caution

Nefadryl Syrup may cause dizziness in some people. Therefore, drive only if you are alert after taking Nefadryl Syrup.

bannner image

Liver

Caution

Take Nefadryl Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Nefadryl Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Caution

Nefadryl Syrup is not recommended for children below 2 years of age unless advised by a doctor.

Country of origin

India
Other Info - NE53147

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Nefadryl Syrup contains Ammonium chloride, Diphenhydramine, Sodium citrate and menthol. Ammonium chloride is an expectorant that increases the volume of fluid in the airways, reduce the stickiness of mucus and helps to remove it from airways. Diphenhydramine is an antihistamine (anti-allergic drug) that blocks the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Sodium citrate is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Thereby, helps to cough out easily. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation.
Nefadryl Syrup may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Nefadryl Syrup to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.
Nefadryl Syrup may cause drowsiness or dizziness. It is not necessary for everyone taking Nefadryl Syrup to experience this side effect. However, avoid driving if you feel drowsy or dizzy after taking Nefadryl Syrup.
You are recommended to take Nefadryl Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after 1 week of using Nefadryl Syrup, please consult your doctor.
You are not recommended to stop taking Nefadryl Syrup without consulting your doctor as it may worsen cough or cause recurring symptoms. Therefore, take Nefadryl Syrup for as long as your doctor has prescribed it and if you experience any difficulty while taking Nefadryl Syrup, please consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button