Natrilam Tablet belongs to the class of medication called 'anti-hypertensive drugs', primarily used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against the blood vessel's walls. This condition makes the heart work harder in pumping blood to the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack and kidney failure.

Natrilam Tablet consists of Amlodipine and Indapamide.  Amlodipine relaxes blood vessels so that blood passes through them easily, thereby lowering blood pressure. Indapamide inhibits excess salt absorption in the body, resulting in increased chloride, sodium, and water excretion through urine. This diuresis process (increased urine production) and excess salts and fluid removal help lower blood pressure. 

The common side effects of Natrilam Tablet include nausea, stomach pain, headache, sleepiness, ankle swelling, flushing (warm sensation in the face, ears, neck, and trunk), palpitations (pounding heartbeat), constipation, muscle pain, and tiredness. Most of these side effects resolve gradually over time and do not usually require medical attention. However, if you notice any side effects that are not manageable, it is advised to consult your doctor.

Try not to stop taking this medicine on your own. Stopping Natrilam Tablet may worsen your condition and increase the risk of a heart attack. Tell your doctor if you are sensitive to Natrilam Tablet , have any kidney/liver diseases, or have heart problems like aortic/mitral stenosis (reduced blood flow from the left atrium to the left ventricle due to narrowing of the mitral valve). Natrilam Tablet is not recommended for use in pregnancy and breastfeeding. Natrilam Tablet may cause dizziness; hence it is advised to drive only when you are alert.

Natrilam Tablet is composed of two medicines, namely: Amlodipine and Indapamide. Amlodipine belongs to the class of calcium channel blockers that relaxes blood vessels so that blood passes through them easily, lowering blood pressure. Indapamide is a thiazide diuretic that inhibits excess salt absorption in the body, resulting in increased chloride, sodium, and water excretion through urine. This diuresis process (increased urine production) and excess salts and fluid removal help lower blood pressure.

• Blurred Vision 
• Sweating
• Tiredness 
• Dehydration 
• Constipation 
• Dizziness 
• Headache 
• Nausea 
• Cold hands or feet 
• Muscle cramps
• Difficulty breathing
• Tightness in the chest

Do not use Natrilam Tablet if you are allergic to any of its components. Let your doctor know if you have any history of severe kidney or liver diseases, low potassium levels (hypokalaemia), chest pain (angina), poor blood circulation or controlled heart failure, first-degree heart block, diabetes, thyrotoxicosis (a condition caused by an overactive thyroid gland), liver problems and adrenal gland diseases. Let your doctor know if you have anuria (kidneys aren't producing urine), fluid or electrolyte imbalance, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), gout, abnormal heart rhythms, thyroid disorders or asthma. Consult your doctor if you are pregnant or breastfeeding. Natrilam Tablet can increase the chances of light-headedness, so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness. Natrilam Tablet is not recommended in people less than 18 years of age.

Drug-Drug Interaction: Natrilam Tablet may interact with other diuretic medications (hydrochlorothiazide, furosemide, torsemide), anti-hypertensive drugs (chlorthalidone, ramipril, metoprolol, lisinopril,  candesartan, baclofen, levodopa, clonidine), drugs treating mental illness (alprazolam, risperidone, amisulpride, pimozide), painkillers (ibuprofen, naproxen), anti-depressants (lithium, duloxetine), Vitamins (vitamin D, cholecalciferol (vitamin D3)), heart-related drugs (amiodarone, digoxin, sotalol), diabetic drugs (insulin glargine, metformin), drugs treating stomach acid (esomeprazole), fits medicine (clonazepam), pain medicine (oxycodone), corticosteroids (prednisone), drugs treating impotence (sildenafil), and multivitamin/minerals.

Drug-Food Interaction: Natrilam Tablet may interact or may have decreased effect when used with alcohol and large amounts of orange juice.

Drug-Disease Interaction: Let your doctor know if you have any severe kidney or liver diseases, low potassium levels (hypokalaemia), chest pain (angina), poor blood circulation or controlled heart failure, first-degree heart block, diabetes, thyrotoxicosis (a condition caused by an overactive thyroid gland), liver problems, adrenal gland diseases, anuria (kidneys aren't producing urine), fluid or electrolyte imbalance, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), gout, abnormal heart rhythms, thyroid disorders or asthma.

• SILDENAFIL
• OXYCODONE
• PREDNISONE
• CLONAZEPAM
• ESOMEPRAZOLE
• INSULIN GLARGINE
• METFORMIN
• CHOLECALCIFEROL
• RISPERIDONE
• DULOXETINE
• DIGOXIN
• AMIODARONE
• LISINOPRIL
• CANDESARTAN
• LITHIUM
• NAPROXEN
• AMISULPRIDE
• IBUPROFEN
• PIMOZIDE
• ALPRAZOLAM
• CLONIDINE
• BACLOFEN
• LEVODOPA
• METOPROLOL
• CHLORTHALIDONE
• HYDROCHLOROTHIAZIDE
• FUROSEMIDE
• TORSEMIDE
• RAMIPRIL

• Keep your weight under control with a body mass index (BMI) between 19.5 and 24.9.

• Quit smoking to lower the risk of heart disease. 

• Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress.

• Monitor your blood pressure daily, and if you notice any fluctuations frequently, please get in touch with your doctor immediately.

• Try including heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil that help in lowering your elevated blood pressure.

• Monitor your blood pressure regularly and seek medical advice if you notice any drastic fluctuations.

• Let your doctor know if you are advised for any blood examinations as diuretics like Indapamide can cause changes in the laboratory parameters like low potassium levels in the blood, low sodium in the blood, low blood pressure, increase in uric acid, increase in blood glucose levels in diabetic patients, increase in calcium levels in the blood, and increase in the liver enzyme levels. 

• Let your anaesthetist or medical staff know that you are taking Natrilam Tablet since Natrilam Tablet  can lower blood pressure levels when certain anaesthetic medications are given during any operation or surgery.

• Athletes should be aware that Indapamide in Natrilam Tablet gives a positive reaction in doping tests.

Hypertension: When blood pressure is excessively high, it becomes a chronic problem. Blood pressure is determined by how much blood the heart pumps and how much resistance the arteries provide to the flow of blood. Blood pressure rises, and arteries constrict as the heart pumps more blood. If not treated, uncontrolled blood pressure can cause major cardiac conditions, including heart attack and stroke. Kidney failure and brain damage are two more effects of high blood pressure. Headache, bleeding from the nose, nausea, and chest discomfort are a few signs of hypertension.