Minirin Melt 120 mcg Tablet is used to treat diabetes insipidus, post-hypophysectomy polyuria (extreme urination), polydipsia (extreme thirst), and bedwetting. Diabetes insipidus is a condition in which the body fails to control water balance, resulting in excessive urination. Hypophysectomy is the surgical removal of the hypophysis (pituitary gland).

Minirin Melt 120 mcg Tablet contains Desmopressin, a human-made form (synthetic) of Vasopressin. Vasopressin is an antidiuretic (that controls fluid balance) hormone, synthesized in the pituitary gland's hypothalamus. When your body cannot produce enough vasopressin, Minirin Melt 120 mcg Tablet is given to replace a low vasopressin level. It mimics the natural hormone, vasopressin and works by reabsorbing water from the kidneys, which controls excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced and controls bedwetting in children. Being an anti-haemophilic agent, Minirin Melt 120 mcg Tablet also reduces the bleeding tendency in haemophilia (bleeding disorder) by promoting the release of blood clotting factors.

Your doctor will decide the dosage depending on your medical condition. The common side effects of Minirin Melt 120 mcg Tablet include headache, nausea, abdominal cramps, and flushing (sense of warmth in the face, ears, neck, and trunk). Although not everyone experiences these side effects, if they occur, seek medical attention.

Before starting Minirin Melt 120 mcg Tablet , let your doctor know if you have any medical history of severe kidney disease or hyponatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, and fluid retention. While using Minirin Melt 120 mcg Tablet , limit water and other fluids' intake since it may lead to electrolyte imbalance. Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime, leading to increased urination. Pregnant and breastfeeding women should consult their doctor before using Minirin Melt 120 mcg Tablet . Do not take or stop this medicine if the doctor did not advise you to do so.

Minirin Melt 120 mcg Tablet is a hormone analogue that treats diabetes insipidus, post-hypophysectomy polyuria (extreme urination) or polydipsia (excessive thirst), and bedwetting. It contains Desmopressin, a synthetic form of Vasopressin (antidiuretic hormone), which mimics the natural hormone vasopressin and works by limiting the amount of water eliminated in the urine, thus controlling excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced, thereby preventing the urinary bladder from filling up at night time and controlling bedwetting in children. Being an anti-haemophilic agent, Minirin Melt 120 mcg Tablet also reduces the bleeding tendency in haemophilia (bleeding disorder) by promoting the release of blood clotting factors. 

• Headache
• Nausea
• Abdominal cramp
• Flushing (sense of warmth in the face, ears, neck and trunk) 

Before starting Minirin Melt 120 mcg Tablet , let your doctor know if you have any medical history of severe kidney disease, hyponatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. While using Minirin Melt 120 mcg Tablet , limit water and other fluids' intake since it may lead to electrolyte imbalance. Inform your doctor if you have any allergic reactions or lactose intolerance before using Minirin Melt 120 mcg Tablet . Please consult your doctor before starting Minirin Melt 120 mcg Tablet if you are pregnant, planning to conceive or are a breastfeeding mother. It is not recommended to consume alcohol since it may worsen the side effects and increase urination. 

Drug-Drug Interaction: Minirin Melt 120 mcg Tablet may interact with fits medicine (lamotrigine), antidepressants (escitalopram, fluoxetine, sertraline), and water pills (furosemide).

Drug-Food Interaction: Avoid alcohol since it may worsen the side effects and increase urination. 

Drug-Disease Interaction: Tell your doctor before taking Minirin Melt 120 mcg Tablet if you have a medical history of kidney disease, hyponatremia (low sodium levels in your body), severe thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. 

• LAMOTRIGINE
• ESCITALOPRAM
• FLUOXETINE
• SERTRALINE
• FUROSEMIDE

• Take the medication as directed by the doctor and at regular intervals if you take Minirin Melt 120 mcg Tablet for more than once per day. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Minirin Melt 120 mcg Tablet .

• Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.

• Eat at regular intervals.

• Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime since it can lead to increased urination. 

• Avoid activities that cause dehydration, such as excessive physical exercise or spending time in the heat.

• Regular monitoring of electrolytes is essential to rule out chances of fluid imbalance.

• If you are frequently urinating, it is advised to consult your endocrinologist to check for any hormonal abnormalities.

• You may also be advised for any CT, or MRI scans to know the functioning of your pituitary gland.

• Kidney functioning tests may be advised by your doctor to monitor for any renal impairment.

Diabetes insipidus: It is a condition in which the body fails to control fluid balance, resulting in excessive urination. It is caused by two conditions: A) Central diabetes insipidus is a condition when your pituitary gland cannot produce enough vasopressin (an antidiuretic hormone that maintains fluid balance). B) Nephrogenic diabetes insipidus: Though you make enough vasopressin, your kidneys may not respond to vasopressin, which regulates fluid balance.

Hypophysectomy: It is the surgical removal of the hypophysis (pituitary gland) to treat cancerous or benign tumours.