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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:18 PM IST
Minirin Melt 120 mcg Tablet 10's(Corona) is used to treat diabetes insipidus, post-hypophysectomy polyuria (extreme urination) polydipsia (extreme thirst), and bedwetting. It contains Desmopressin, which works by reabsorbing water from the kidneys and also decreases the amount of urine produced and controls bedwetting in children. Additionally, it reduces bleeding tendency in haemophilia (bleeding disorder) by promoting the release of blood clotting factors. It may cause common side effects such as headache, nausea, abdominal cramp, flushing (sense of warmth in the face, ears, neck, and trunk). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Corona Remedies Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Minirin Melt 120 mcg Tablet 10's(Corona)

Minirin Melt 120 mcg Tablet 10's(Corona) is used to treat diabetes insipidus, post-hypophysectomy polyuria (extreme urination), polydipsia (extreme thirst), and bedwetting. Diabetes insipidus is a condition in which the body fails to control water balance, resulting in excessive urination. Hypophysectomy is the surgical removal of the hypophysis (pituitary gland).

Minirin Melt 120 mcg Tablet 10's(Corona) contains Desmopressin, a human-made form (synthetic) of Vasopressin. Vasopressin is an antidiuretic (that controls fluid balance) hormone, synthesized in the pituitary gland's hypothalamus. When your body cannot produce enough vasopressin, Minirin Melt 120 mcg Tablet 10's(Corona) is given to replace a low vasopressin level. It mimics the natural hormone, vasopressin and works by reabsorbing water from the kidneys, which controls excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced and controls bedwetting in children. Being an anti-haemophilic agent, Minirin Melt 120 mcg Tablet 10's(Corona) also reduces the bleeding tendency in haemophilia (bleeding disorder) by promoting the release of blood clotting factors.

Your doctor will decide the dosage depending on your medical condition. The common side effects of Minirin Melt 120 mcg Tablet 10's(Corona) include headache, nausea, abdominal cramps, and flushing (sense of warmth in the face, ears, neck, and trunk). Although not everyone experiences these side effects, if they occur, seek medical attention.

Before starting Minirin Melt 120 mcg Tablet 10's(Corona), let your doctor know if you have any medical history of severe kidney disease or hyponatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, and fluid retention. While using Minirin Melt 120 mcg Tablet 10's(Corona), limit water and other fluids' intake since it may lead to electrolyte imbalance. Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime, leading to increased urination. Pregnant and breastfeeding women should consult their doctor before using Minirin Melt 120 mcg Tablet 10's(Corona). Do not take or stop this medicine if the doctor did not advise you to do so.

Uses of Minirin Melt 120 mcg Tablet 10's(Corona)

Treatment of Diabetes insipidus, Post-hypophysectomy polyuria (polydipsia), and Bedwetting.

Medicinal Benefits

Minirin Melt 120 mcg Tablet 10's(Corona) is a hormone analogue that treats diabetes insipidus, post-hypophysectomy polyuria (extreme urination) or polydipsia (excessive thirst), and bedwetting. It contains Desmopressin, a synthetic form of Vasopressin (antidiuretic hormone), which mimics the natural hormone vasopressin and works by limiting the amount of water eliminated in the urine, thus controlling excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced, thereby preventing the urinary bladder from filling up at night time and controlling bedwetting in children. Being an anti-haemophilic agent, Minirin Melt 120 mcg Tablet 10's(Corona) also reduces the bleeding tendency in haemophilia (bleeding disorder) by promoting the release of blood clotting factors. 

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Minirin Melt 120 mcg Tablet 10's(Corona)

  • Headache
  • Nausea
  • Abdominal cramp
  • Flushing (sense of warmth in the face, ears, neck and trunk) 

Drug Warnings

Before starting Minirin Melt 120 mcg Tablet 10's(Corona), let your doctor know if you have any medical history of severe kidney disease, hyponatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. While using Minirin Melt 120 mcg Tablet 10's(Corona), limit water and other fluids' intake since it may lead to electrolyte imbalance. Inform your doctor if you have any allergic reactions or lactose intolerance before using Minirin Melt 120 mcg Tablet 10's(Corona). Please consult your doctor before starting Minirin Melt 120 mcg Tablet 10's(Corona) if you are pregnant, planning to conceive or are a breastfeeding mother. It is not recommended to consume alcohol since it may worsen the side effects and increase urination. 

Drug Interactions

Drug-Drug Interaction: Minirin Melt 120 mcg Tablet 10's(Corona) may interact with fits medicine (lamotrigine), antidepressants (escitalopram, fluoxetine, sertraline), and water pills (furosemide).

Drug-Food Interaction: Avoid alcohol since it may worsen the side effects and increase urination. 

Drug-Disease Interaction: Tell your doctor before taking Minirin Melt 120 mcg Tablet 10's(Corona) if you have a medical history of kidney disease, hyponatremia (low sodium levels in your body), severe thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. 

Drug-Drug Interactions Checker List

  • LAMOTRIGINE
  • ESCITALOPRAM
  • FLUOXETINE
  • SERTRALINE
  • FUROSEMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Minirin Melt 120 mcg Tablet 10's(Corona) for more than once per day. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Minirin Melt 120 mcg Tablet 10's(Corona).

  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.

  • Eat at regular intervals.

  • Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime since it can lead to increased urination. 

  • Avoid activities that cause dehydration, such as excessive physical exercise or spending time in the heat.

Special Advise

  • Regular monitoring of electrolytes is essential to rule out chances of fluid imbalance.

  • If you are frequently urinating, it is advised to consult your endocrinologist to check for any hormonal abnormalities.

  • You may also be advised for any CT, or MRI scans to know the functioning of your pituitary gland.

  • Kidney functioning tests may be advised by your doctor to monitor for any renal impairment.

Disease/Condition Glossary

Diabetes insipidus: It is a condition in which the body fails to control fluid balance, resulting in excessive urination. It is caused by two conditions: A) Central diabetes insipidus is a condition when your pituitary gland cannot produce enough vasopressin (an antidiuretic hormone that maintains fluid balance). B) Nephrogenic diabetes insipidus: Though you make enough vasopressin, your kidneys may not respond to vasopressin, which regulates fluid balance.

Hypophysectomy: It is the surgical removal of the hypophysis (pituitary gland) to treat cancerous or benign tumours.

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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects and increase urination.

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Pregnancy

Caution

Minirin Melt 120 mcg Tablet 10's(Corona) is a pregnancy category B drug. It can cause pre-eclampsia in pregnant women leading to high blood pressure, oedema (swelling due to the build-up of fluid) and proteinuria (protein in the urine). Please consult your doctor before starting Minirin Melt 120 mcg Tablet 10's(Corona) if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Minirin Melt 120 mcg Tablet 10's(Corona) is excreted into the breast milk when used by a breastfeeding mother. Please seek medical advice before you start Minirin Melt 120 mcg Tablet 10's(Corona) if you are nursing.

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Driving

Caution

Do not drive or operate machinery if you experience any unmanageable side effects with Minirin Melt 120 mcg Tablet 10's(Corona).

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Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment when you are prescribed Minirin Melt 120 mcg Tablet 10's(Corona).

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Kidney

Caution

Minirin Melt 120 mcg Tablet 10's(Corona) is contraindicated in patients with moderate to severe renal impairment. Please let your doctor know if you have any history of kidney diseases when prescribed Minirin Melt 120 mcg Tablet 10's(Corona).

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Children

Safe if prescribed

Minirin Melt 120 mcg Tablet 10's(Corona) can be prescribed to children by the doctor, depending on the disease. The doctor decides the right dose for a child based on his/her age and weight.

Country of origin

India

Manufacturer/Marketer address

Corona House, Block C, Mondeal Business Park, Near Gurudwara,, S. G. Highway, Thaltej, Thaltej, Ahmedabad, Gujarat 380059
Other Info - MIN0643

Author Details

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FAQs

Minirin Melt 120 mcg Tablet 10's(Corona) is a hormone analogue that belongs to the class of ‘antihemophilic agents’ primarily used to treat diabetes insipidus, post-hypophysectomy polyuria (extreme urination), polydipsia (extreme thirst), and bedwetting. Diabetes insipidus is a condition in which the body fails to control water balance, resulting in excessive urination. Hypophysectomy is the surgical removal of the hypophysis (pituitary gland).
Minirin Melt 120 mcg Tablet 10's(Corona) contains Desmopressin, a human-made form of vasopressin (antidiuretic hormone). When your body cannot produce enough vasopressin, Minirin Melt 120 mcg Tablet 10's(Corona) is used to replace it. It helps treat diabetes insipidus, post-hypophysectomy polyuria or polydipsia, and bedwetting by causing water reabsorption in the kidneys and reducing the amount of urine to be filled up in the bladder.
Minirin Melt 120 mcg Tablet 10's(Corona) does not cause weight gain. But it may cause fluid overload as a side effect by reducing the amount of fluid to be urinated. This fluid overload can result in weight gain.
Minirin Melt 120 mcg Tablet 10's(Corona) does not cure bedwetting, but it helps control bedwetting. It is usually prescribed at the night time to prevent frequent urination.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
Optimal intake of fluids is recommended. However, avoid excess intake of water and other liquids like coffee, tea, cola, and energy drinks, leading to worsening of electrolyte imbalance.
Before starting Minirin Melt 120 mcg Tablet 10's(Corona), let your doctor know if you have any medical history of severe kidney disease, hyponatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. While using Minirin Melt 120 mcg Tablet 10's(Corona), limit water and other fluids intake since it may lead to electrolyte imbalance. Tell your doctor about allergic reactions or lactose intolerance before using Minirin Melt 120 mcg Tablet 10's(Corona). Also, let your doctor know if you are pregnant, planning to conceive or are a breastfeeding mother. It is not recommended to consume alcohol since it may worsen the side effects and increase urination.
Your doctor will decide the duration of treatment depending on your medical condition and response to the treatment.
Minirin Melt 120 mcg Tablet 10's(Corona) contains Desmopressin, a human-made form (synthetic) of Vasopressin. Vasopressin is an antidiuretic (that controls fluid balance) hormone.
Swallow it whole with water; do not crush, break, or chew it. Follow the dose and duration as directed by the physician.
It is unsafe to consume alcohol since it may worsen the side effects and increase urination.
Minirin Melt 120 mcg Tablet 10's(Corona) can cause pre-eclampsia in pregnant women, leading to high blood pressure, oedema (swelling due to the build-up of fluid), and proteinuria (protein in the urine). When used by a breastfeeding mother, Minirin Melt 120 mcg Tablet 10's(Corona) is excreted into the breast milk. So, caution should be exercised. Pregnant and breastfeeding women should not use Minirin Melt 120 mcg Tablet 10's(Corona) unless prescribed by the doctor.
Minirin Melt 120 mcg Tablet 10's(Corona) is contraindicated in patients with moderate to severe renal impairment. So, it is essential to inform your doctor about your condition. Your doctor will prescribe the medication only if the benefits outweigh the risks.
The common side effects of Minirin Melt 120 mcg Tablet 10's(Corona) include headache, nausea, abdominal cramps, and flushing (sense of warmth in the face, ears, neck, and trunk). Although not everyone experiences these side effects, if they occur, seek medical attention.

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