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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Mific Plus 100mg Injection is an antibiotic used in treating bacterial infections. This medicine stops the growth of bacteria and thereby helps reduce various bacterial infections of the ear, lungs, skin, nose, urinary tract, and throat. This medicine is not effective for treating viral infections.
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Composition :

MINOCYCLINE-100MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Mific Plus 100mg Injection

Mific Plus 100mg Injection belongs to the class of 'antibiotics', primarily used to treat bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. 

Mific Plus 100mg Injection contains 'Minocycline, a tetracycline antibiotic.' It works by preventing the synthesis of bacterial proteins, the primary cursors for carrying out bacteria's vital functions. This process further inhibits bacterial growth.

Mific Plus 100mg Injection will be administered by a healthcare professional. Common side effects of Mific Plus 100mg Injection include stomach upset, tinnitus/ringing in the ear, nausea, vomiting, diarrhoea, headache, dizziness, light-headedness, pain, redness, and swelling at the injection site. Most of these side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Let your doctor know if you have any kidney or liver diseases and allergic reactions to medicines. It is advised to consult your doctor if you are pregnant or breastfeeding before taking Mific Plus 100mg Injection. This medicine may interfere with your driving ability since it may cause light-headedness/dizziness; in such cases, please do not drive until you are alert. Avoid or limit alcohol consumption. Mific Plus 100mg Injection is not recommended in children below eight years of age.

Uses of Mific Plus 100mg Injection

Treatment of Bacterial infections

Directions for Use

Mific Plus 100mg Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Mific Plus 100mg Injection contains 'Minocycline,' an antibiotic that treats various bacterial infections affecting the eyes, ears, nose, throat, respiratory system (chest infections), skin (acne), prostate, and urinary tract. It works by preventing the synthesis of bacterial proteins, the primary cursors for carrying out bacteria's vital functions. Mific Plus 100mg Injection also effectively treats meningitis, acne, upper respiratory tract infections, Q fever or tick fever (bacterial infection caused by the bite of infected ticks), brucellosis (infection spread from animals), and psittacosis (infections spread from birds). It is also used to treat sexually transmitted diseases like syphilis and gonorrhoea.

How Mific Plus 100mg Injection Works

Mific Plus 100mg Injection contains 'Minocycline, a tetracycline antibiotic.' It works by preventing the synthesis of bacterial proteins, the primary cursors for carrying out bacteria's vital functions. This process further inhibits bacterial growth.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mific Plus 100mg Injection

  • Stomach upset
  • Tinnitus/ringing in the ear
  • Nausea
  • Vomiting
  • Diarrhoea 
  • Light-headedness
  • Dizziness
  • Headache
  • Pain, redness, and swelling at the injection site

What if I have taken an overdose of Mific Plus 100mg Injection

Mific Plus 100mg Injection is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include dizziness, nausea, and vomiting. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Let your doctor know if you have any liver or kidney diseases and allergic reactions to tetracycline antibiotics. Mific Plus 100mg Injection may induce photosensitivity and make your skin more sensitive to the sun; hence apply sunscreen when you step out while being treated with Mific Plus 100mg Injection. Use of Mific Plus 100mg Injection during tooth development (the last half of pregnancy, infancy, and childhood under the age of 8 years) may cause permanent discolouration of the teeth. Please seek medical advice if you are pregnant or breastfeeding before taking Mific Plus 100mg Injection. This medicine may cause dizziness; hence drive or operate machinery only when you are alert. Mific Plus 100mg Injection may cause light-headedness; hence avoid or limit alcohol consumption. Mific Plus 100mg Injection is not recommended in children below eight years of age.

Drug-Drug Interactions

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MinocyclineEtretinate
Critical
MinocyclineAcitretin
Critical

Drug-Drug Interactions

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MinocyclineEtretinate
Critical
How does the drug interact with Mific Plus 100mg Injection:
Co-administration of Etretinate with Mific Plus 100mg Injection may raise the chance of developing pseudotumor cerebri, an uncommon but serious illness brought on by elevated brain pressure.

How to manage the interaction:
Taking Mific Plus 100mg Injection with Etretinate is generally avoided as it can result in an interaction. However, if you experience headache, nausea, vomiting, or visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MinocyclineAcitretin
Critical
How does the drug interact with Mific Plus 100mg Injection:
Co-administration of Acitretin with Mific Plus 100mg Injection may increase the risk of a serious condition called pseudomotor cerebral (false brain tumour).

How to manage the interaction:
There's a possible interaction between Acitretin and Mific Plus 100mg Injection should be used together only if prescribed by a doctor. However, if you develop symptoms such as nausea, vomiting, headache, or visual disturbances during treatment with either medication, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
MinocyclineTretinoin
Critical
How does the drug interact with Mific Plus 100mg Injection:
Co-administration of Tretinoin with Mific Plus 100mg Injection can increase the risk of side effects like pseudotumor cerebri (increased pressure in the brain)

How to manage the interaction:
Taking Tretinoin with Mific Plus 100mg Injection is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MinocyclineMipomersen
Severe
How does the drug interact with Mific Plus 100mg Injection:
Co-administration of mipomersen with Mific Plus 100mg Injection can cause liver damage.

How to manage the interaction:
Although taking mipomersen and Mific Plus 100mg Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MinocyclineKetoconazole
Severe
How does the drug interact with Mific Plus 100mg Injection:
Co-administration of ketoconazole with Mific Plus 100mg Injection can increase the risk of liver damage.

How to manage the interaction:
Although taking ketoconazole and Mific Plus 100mg Injection together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MinocyclineCholera, live attenuated
Severe
How does the drug interact with Mific Plus 100mg Injection:
Co-administration of cholera live attenuated with Mific Plus 100mg Injection may reduce the activity of cholera live attenuated.

How to manage the interaction:
Although taking cholera live attenuated and Mific Plus 100mg Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. It is advised to take cholera vaccine at least 14 days after stopping Mific Plus 100mg Injection treatment. Do not discontinue any medications without consulting a doctor.
MinocyclineMethoxyflurane
Severe
How does the drug interact with Mific Plus 100mg Injection:
Taking methoxyflurane with Mific Plus 100mg Injection may increase the risk of kidney damage.

How to manage the interaction:
Although taking methoxyflurane and Mific Plus 100mg Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as swelling, weight gain, feeling short of breath, drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting, pain in your lower back, and urinating, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MinocyclineTeriflunomide
Severe
How does the drug interact with Mific Plus 100mg Injection:
Co-administration of teriflunomide with Mific Plus 100mg Injection can increase the risk or severity of liver damage.

How to manage the interaction:
Although taking teriflunomide and Mific Plus 100mg Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MinocyclineCholera, live attenuated
Severe
How does the drug interact with Mific Plus 100mg Injection:
Co-administration of cholera live attenuated with Mific Plus 100mg Injection may reduce the activity of cholera live attenuated.

How to manage the interaction:
Although taking cholera live attenuated and Mific Plus 100mg Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. It is advised to take cholera vaccine at least 14 days after stopping Mific Plus 100mg Injection treatment. Do not discontinue any medications without consulting a doctor.
MinocyclineRetinol (vit a)
Severe
How does the drug interact with Mific Plus 100mg Injection:
Taking retinol (vitamin A) with Mific Plus 100mg Injection may increase the risk of pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking retinol (vitamin A) and Mific Plus 100mg Injection together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult a doctor immediately if you experience headaches, nausea, vomiting, and visual disturbances. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands often to maintain cleanliness.
  • Avoid sharing personal items like shaving razors.
  • Include whole-grain foods like multigrain bread and brown rice in your diet. 
  • Taking probiotics after an antibiotic treatment reduces the risk of antibiotic-associated diarrhoea. Try taking yoghurt, cheese, sauerkraut, and kimchi that help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet that is easily digested by gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics. 
  • Avoid intake of alcoholic beverages as it can make you dehydrated and affect your sleep. 
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep. 

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Mific Plus 100mg Injection Substitute

Substitutes safety advice
  • Minoz OD 100 Capsule 10's

    48.15per tablet
  • Minoz 100 Tablet 10's

    42.75per tablet
  • Cynomycin 100mg Capsule 4's

    72.00per tablet
  • CNN 100 MR Tablet 10's

    46.49per tablet
  • Minolox 100 Tablet 10's

    45.36per tablet
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Alcohol

Caution

Alcohol consumption may worsen the side effects of Mific Plus 100mg Injection like dizziness. It is better to avoid alcohol while you are being treated with Mific Plus 100mg Injection.

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Pregnancy

Unsafe

Mific Plus 100mg Injection is not recommended during pregnancy since it affects tooth and bone development in the unborn baby. Please consult your doctor before taking Mific Plus 100mg Injection if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Mific Plus 100mg Injection is excreted into breast milk and may affect the infant. Please consult your doctor before taking Mific Plus 100mg Injection if you are breastfeeding.

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Driving

Caution

Mific Plus 100mg Injection may cause side effects like dizziness that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.

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Liver

Caution

Please take Mific Plus 100mg Injection only with the doctor's advice if you have a history of liver diseases/conditions.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases or impairment before taking Mific Plus 100mg Injection.

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Children

Caution

Mific Plus 100mg Injection is not recommended in children younger than eight years. Please consult a doctor for more information.

FAQs

Mific Plus 100mg Injection belongs to the class of 'antibiotics', primarily used to treat bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly.
Mific Plus 100mg Injection belongs to the class of antibiotics, primarily used to treat bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and cause illness. It can infect any part of the body and multiply very quicklyMific Plus 100mg Injection is an antibiotic that treats bacterial infections.
It works by inhibiting bacterial protein synthesis, which further retards bacterial growth.
Mific Plus 100mg Injection can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor before you start Mific Plus 100mg Injection if you are undergoing any vaccinations.
Mific Plus 100mg Injection can make your skin more sensitive to the harmful effects of sunlight. Hence, applying sunscreen and wearing protective clothing while using Mific Plus 100mg Injection is advised. It is also recommended to avoid tanning booths and sunlamps.
Iron supplements and antacids (containing calcium, magnesium and aluminium) may lower the absorption and efficiency of Mific Plus 100mg Injection. Hence maintain at least 2 hours gap between Mific Plus 100mg Injection and other medications.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - MIF0034

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