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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Methylgon 0.2mg Injection is used to prevent and stop heavy bleeding after childbirth or after a miscarriage in cesarean section. Besides this, it is also used to improve uterine contraction (antepartum) during postpartum. It contains Methylergometrine, which stimulates uterine muscles and increases the uterus contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), increasing contractions and producing labour. As a result, these increased uterine contractions help in the child's delivery and substantially reduce excessive uterine bleeding. In some cases, it may cause common side effects such as nausea, vomiting, stomach pain, and mild headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components and about all the medications you are taking and pre-existing medical conditions.
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Synonym

METHYLERGOMETRINE MALEATE

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Methylgon 0.2mg Injection

Methylgon 0.2mg Injection belongs to the class of medication called 'ergot alkaloids' or 'uterotonic' primarily used to prevent and stop heavy bleeding (postpartum-third stage of labour bleeding) after childbirth or after a miscarriage in cesarean section. Besides this, it is also used to improve uterine contraction (antepartum) and produce uterine contraction during the third stage of labor (postpartum). Postpartum haemorrhage is heavy bleeding (more than normal) after the birth of the baby.

Methylgon 0.2mg Injection contains a semi-synthetic ergot alkaloid 'Methylergometrine', that stimulates uterine muscles and increases the uterus' contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), increasing contractions and producing labour. As a result, these increased uterine contractions help in the child's delivery and substantially reduce excessive uterine bleeding. 

Methylgon 0.2mg Injection will be administered by a healthcare professional. Do not self-administer. The most common side effects of Methylgon 0.2mg Injection are nausea, vomiting, stomach pain, and mild headache in some cases. Most of these side effects of Methylgon 0.2mg Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you ever had surgery on the uterus, cesarean, or premature labour, please inform your doctor to avoid any complications. If you have been given prostaglandins, then do not take Methylgon 0.2mg Injection; if both medicines are taken together, it can increase the contractions. Methylgon 0.2mg Injection should not be used for a prolonged time if the contractions do not increase or have severe pre-eclamptic toxemia (high blood pressure, protein in the urine, and swelling), blood or heart circulation problem. 

Uses of Methylgon 0.2mg Injection

Treatment of Postpartum haemorrhage.

Medicinal Benefits

Methylgon 0.2mg Injection contains a semi-synthetic ergot alkaloid 'Methylergometrine' primarily used to stop heavy bleeding postpartum, i.e. third stage of labour bleeding after childbirth or after a miscarriage in cesarean section. Additionally, it plays a significant role in birth by increasing uterus contractions and inducing labour in pregnant women. Methylgon 0.2mg Injection works by stimulating uterine muscles and expanding the uterus' contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), increases the contraction,s and hence induces labour. As a result, these increased uterine contractions help deliver the child and substantially reduce excessive uterine bleeding.

Directions for Use

Methylgon 0.2mg Injection will be administered by a healthcare professional under strict medical supervision. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Methylgon 0.2mg Injection

  • Nausea
  • Vomiting
  • Headache
  • Stomach pain

Drug Warnings

Do not take Methylgon 0.2mg Injection if you are allergic to Methylgon 0.2mg Injection or any of its ingredients. Increasing the dose of Methylgon 0.2mg Injection can be harmful if your womb already has too strong contractions, any obstructions in the pathway that might prevent the delivery or if the baby is not receiving a sufficient oxygen supply. Also, the use of Methylgon 0.2mg Injection is not advisable if the baby is wrongly positioned in the birth canal, the baby’s head is too large to fit through the pelvis, the placenta lies near the neck of the womb, the placenta separates from the womb before birth, the womb is over-extended and likely to tear (in case you are carrying more than one baby). If you have been given prostaglandins, do not use Methylgon 0.2mg Injection within 6 hours as both medications, if taken together, can increase the contractions. Methylgon 0.2mg Injection should not be used for a prolonged time if the contractions do not increase or if you have severe pre-eclamptic toxaemia (high blood pressure, protein in the urine, and swelling) or blood or heart circulation problems.

Drug Interactions

Drug-Drug Interaction: Methylgon 0.2mg Injection may interact with anaesthetics (sevoflurane, halothane, cyclopropane, desflurane), other medicines used to start labour (prostaglandins), anti-diuretic hormone (vasopressin), a neurotransmitter (dopamine), anti-sickness medicine (ondansetron), sympathomimetic agents (epinephrine).

Drug-Food Interaction: Grapefruit juice intake should be avoided with Methylgon 0.2mg Injection as it may interact with Methylgon 0.2mg Injection to produce unpleasant side effects.

Drug-Disease Interaction: Methylgon 0.2mg Injection should not be given to patients with previous cesarean section, hypertension (high blood pressure), heart problem, cervical cancer, herpes infection, kidney problem, if you are more than 40 weeks pregnant or are more than 35 years age, the pelvis is too small for normal delivery.

Drug-Drug Interactions Checker List

  • PROSTAGLANDINS
  • DESFLURANE
  • CYCLOPROPANE
  • DOPAMINE
  • EPINEPHRINE
  • HALOTHANE
  • ONDANSETRON
  • VASOPRESSIN
  • SEVOFLURANE

Habit Forming

No

Diet & Lifestyle Advise

  • Long walks can help to relieve stress, keep your body strong, and help in easy delivery.
  • Please take a little bit of Castrol oil as it is known to stimulate prostaglandin, which ripens the cervix and get labor started.
  • Some food like dates, raspberry tea leaves are known to ripen the cervix and get labor started.
  • Acupressure also stimulates labor and helps in delivery.

Special Advise

  • Methylgon 0.2mg Injection when given for induction of labor, stimulation of labor and prevention of vaginal bleeding after delivery of the baby especially after caesarean surgery. It must be administered only by the intravenous (IV) or intramuscular (IM) route under medical supervision in a hospital setting only. 

Disease/Condition Glossary

Postpartum haemorrhage: It is a serious but rare condition which causes excessive vaginal bleeding within one day after giving birth to the child. It happens mostly in cases of cesarean birth. When a baby is delivered, the uterus of the body contracts and forces out the placenta. After the placenta's delivery, these contractions put pressure on the bleeding vessels at the place where the placenta was attached, resulting in vaginal bleeding. It is normal to lose some amount of blood after delivery, but if a woman is losing more blood than normal, it can be dangerous. 

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Alcohol

Unsafe

It is not known if alcohol affects Methylgon 0.2mg Injection. Consult your doctor.

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Pregnancy

Unsafe

Methylgon 0.2mg Injection is not recommended for use during pregnancy.

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Breast Feeding

Unsafe

It is advised to avoid breastfeeding for at least 12 hours after taking Methylgon 0.2mg Injection as this medicine may pass into breast milk and can harm a nursing baby.

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Driving

Unsafe

Avoid driving and operating machinery.

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Liver

Safe if prescribed

Methylgon 0.2mg Injection is not known to show any interaction in liver disease.

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Kidney

Caution

Methylgon 0.2mg Injection to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose will be adjusted by your doctor.

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Children

Unsafe

Methylgon 0.2mg Injection is not recommended for children below the age of 18 years. The safety and effectiveness of Methylgon 0.2mg Injection have not been established in children.

Country of origin

India
Other Info - ME16119

Author Details

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FAQs

Methylgon 0.2mg Injection is used to prevent and stop heavy bleeding (postpartum-third stage of labour bleeding) after childbirth or after a miscarriage in cesarean section. Besides this, it is also used to improve uterine contraction (antepartum) and produce uterine contraction during the third stage of labor (postpartum).
Methylgon 0.2mg Injection works by stimulating uterine muscles and increasing the uterus' contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), and increases the contraction, thereby inducing labour pain in pregnant women. As a result, these increased uterine contractions help in the child's delivery and substantially reduce excessive uterine bleeding.
If you have a previous premature delivery or a cesarian section, or cervical surgery, please inform your doctor before starting Methylgon 0.2mg Injection. Also, mention a detailed medical history to your doctor to avoid any complications.
The most common side effects of Methylgon 0.2mg Injection include nausea, vomiting, stomach pain, mild headache. You might also feel increased uterine contractions for some time, but these are manageable under medical supervision.
It is suggested to avoid grapefruit and grapefruit juice while taking Methylgon 0.2mg Injection as it can worsen the side effects of Methylgon 0.2mg Injection.
It is advised to tell your doctor if you are using antifungal medicine (Fluconazole) or other medicine, including prescription and over-the-counter medicines, vitamins, and herbal products, as taking Methylgon 0.2mg Injection with some medications may cause serious side effects.

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