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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
MEM INJECTION 1ML is used to prevent and stop heavy bleeding after childbirth or after a miscarriage in cesarean section. Besides this, it is also used to improve uterine contraction (antepartum) during postpartum. It contains Methylergometrine, which stimulates uterine muscles and increases the uterus contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), increasing contractions and producing labour. As a result, these increased uterine contractions help in the child's delivery and substantially reduce excessive uterine bleeding. In some cases, it may cause common side effects such as nausea, vomiting, stomach pain, and mild headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components and about all the medications you are taking and pre-existing medical conditions.
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Synonym :

METHYLERGOMETRINE MALEATE

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About MEM INJECTION 1ML

MEM INJECTION 1ML belongs to the class of medication called 'ergot alkaloids' or 'uterotonic' primarily used to prevent and stop heavy bleeding (postpartum-third stage of labour bleeding) after childbirth or after a miscarriage in cesarean section. Besides this, it is also used to improve uterine contraction (antepartum) and produce uterine contraction during the third stage of labor (postpartum). Postpartum haemorrhage is heavy bleeding (more than normal) after the birth of the baby.

MEM INJECTION 1ML contains a semi-synthetic ergot alkaloid 'Methylergometrine', that stimulates uterine muscles and increases the uterus' contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), increasing contractions and producing labour. As a result, these increased uterine contractions help in the child's delivery and substantially reduce excessive uterine bleeding. 

MEM INJECTION 1ML will be administered by a healthcare professional. Do not self-administer. The most common side effects of MEM INJECTION 1ML are nausea, vomiting, stomach pain, and mild headache in some cases. Most of these side effects of MEM INJECTION 1ML do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you ever had surgery on the uterus, cesarean, or premature labour, please inform your doctor to avoid any complications. If you have been given prostaglandins, then do not take MEM INJECTION 1ML; if both medicines are taken together, it can increase the contractions. MEM INJECTION 1ML should not be used for a prolonged time if the contractions do not increase or have severe pre-eclamptic toxemia (high blood pressure, protein in the urine, and swelling), blood or heart circulation problem. 

Uses of MEM INJECTION 1ML

Treatment of Postpartum haemorrhage.

Directions for Use

MEM INJECTION 1ML will be administered by a healthcare professional under strict medical supervision. Do not self-administer.

Medicinal Benefits

MEM INJECTION 1ML contains a semi-synthetic ergot alkaloid 'Methylergometrine' primarily used to stop heavy bleeding postpartum, i.e. third stage of labour bleeding after childbirth or after a miscarriage in cesarean section. Additionally, it plays a significant role in birth by increasing uterus contractions and inducing labour in pregnant women. MEM INJECTION 1ML works by stimulating uterine muscles and expanding the uterus' contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), increases the contraction,s and hence induces labour. As a result, these increased uterine contractions help deliver the child and substantially reduce excessive uterine bleeding.

How MEM INJECTION 1ML Works

MEM INJECTION 1ML contains a semi-synthetic ergot alkaloid 'Methylergometrine', that stimulates uterine muscles and increases the uterus' contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), increasing contractions and producing labour. As a result, these increased uterine contractions help in the child's delivery and substantially reduce excessive uterine bleeding.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MEM INJECTION 1ML

  • Nausea
  • Vomiting
  • Headache
  • Stomach pain

What if I have taken an overdose of MEM INJECTION 1ML

The overdose of MEM INJECTION 1ML is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms after receiving MEM INJECTION 1ML, please inform your doctor immediately.

Drug Warnings

Do not take MEM INJECTION 1ML if you are allergic to MEM INJECTION 1ML or any of its ingredients. Increasing the dose of MEM INJECTION 1ML can be harmful if your womb already has too strong contractions, any obstructions in the pathway that might prevent the delivery or if the baby is not receiving a sufficient oxygen supply. Also, the use of MEM INJECTION 1ML is not advisable if the baby is wrongly positioned in the birth canal, the baby’s head is too large to fit through the pelvis, the placenta lies near the neck of the womb, the placenta separates from the womb before birth, the womb is over-extended and likely to tear (in case you are carrying more than one baby). If you have been given prostaglandins, do not use MEM INJECTION 1ML within 6 hours as both medications, if taken together, can increase the contractions. MEM INJECTION 1ML should not be used for a prolonged time if the contractions do not increase or if you have severe pre-eclamptic toxaemia (high blood pressure, protein in the urine, and swelling) or blood or heart circulation problems.

Drug-Drug Interactions

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MethylergometrineKetoconazole
Critical
MethylergometrineRitonavir
Critical

Drug-Drug Interactions

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MethylergometrineKetoconazole
Critical
How does the drug interact with MEM INJECTION 1ML:
Using Ketoconazole with MEM INJECTION 1ML can increase the concentration of MEM INJECTION 1ML, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with MEM INJECTION 1ML is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineRitonavir
Critical
How does the drug interact with MEM INJECTION 1ML:
Taking MEM INJECTION 1ML with Ritonavir can significantly increase the blood levels and effects of MEM INJECTION 1ML.

How to manage the interaction:
Taking MEM INJECTION 1ML with Ritonavir is not recommended, but can be taken together if prescribed by a doctor. In case you experience any side effects like severe abdominal discomfort, nausea, vomiting, tingling or numbness, weakness or pain in the muscles, pale skin, blue or purple discoloration on fingers or toes, tightness or pain in the chest, irregular heartbeat, intense headache, breathing difficulties, confusion, or slurred speech, consult a doctor. Do not discontinue any medications without consulting a doctor.
MethylergometrineVoriconazole
Critical
How does the drug interact with MEM INJECTION 1ML:
Coadministration of MEM INJECTION 1ML with Voriconazole may increase the blood level of MEM INJECTION 1ML.

How to manage the interaction:
Although MEM INJECTION 1ML with Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineClarithromycin
Critical
How does the drug interact with MEM INJECTION 1ML:
When MEM INJECTION 1ML is taken with Clarithromycin, the amount of MEM INJECTION 1ML in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Clarithromycin with MEM INJECTION 1ML is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
MethylergometrineSumatriptan
Critical
How does the drug interact with MEM INJECTION 1ML:
Coadministration of Sumatriptan with MEM INJECTION 1ML can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Sumatriptan with MEM INJECTION 1ML together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MethylergometrineKetoconazole
Critical
How does the drug interact with MEM INJECTION 1ML:
Using Ketoconazole with MEM INJECTION 1ML can increase the concentration of MEM INJECTION 1ML, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with MEM INJECTION 1ML can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineGlyceryl trinitrate
Critical
How does the drug interact with MEM INJECTION 1ML:
Coadministration of MEM INJECTION 1ML with Glyceryl trinitrate can increase the levels and side effects of MEM INJECTION 1ML.

How to manage the interaction:
Taking MEM INJECTION 1ML with Glyceryl trinitrate is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
MethylergometrineItraconazole
Critical
How does the drug interact with MEM INJECTION 1ML:
Co-administration of MEM INJECTION 1ML and Itraconazole may increase the blood levels of MEM INJECTION 1ML.

How to manage the interaction:
MEM INJECTION 1ML and itraconazole may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
MethylergometrineEphedrine
Severe
How does the drug interact with MEM INJECTION 1ML:
Taking Ephedrine with MEM INJECTION 1ML may lead to an increase in the risk of high blood pressure.

How to manage the interaction:
Although taking Ephedrine with MEM INJECTION 1ML may lead to an interaction, it can be taken if prescribed by the doctor. It is advised to maintain your blood pressure. Do not discontinue any medications without a doctor's advice.
MethylergometrinePhenylephrine
Severe
How does the drug interact with MEM INJECTION 1ML:
Taking Phenylephrine with MEM INJECTION 1ML can led to side effects like increased blood pressure.

How to manage the interaction:
Taking Phenylephrine with MEM INJECTION 1ML can lead to an interaction but can be taken if prescribed by the doctor. It is advised to monitor your blood pressure regularly. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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METHYLERGOMETRINE-0.2MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLERGOMETRINE-0.2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of MEM INJECTION 1ML with Grapefruit and Grapefruit may lead to an increase in the effectiveness of MEM INJECTION 1ML. Avoid or limit grapefruit and grapefruit juice consumption with MEM INJECTION 1ML. This can increase the risk or severity of side effects.

Diet & Lifestyle Advise

  • Long walks can help to relieve stress, keep your body strong, and help in easy delivery.
  • Please take a little bit of Castrol oil as it is known to stimulate prostaglandin, which ripens the cervix and get labor started.
  • Some food like dates, raspberry tea leaves are known to ripen the cervix and get labor started.
  • Acupressure also stimulates labor and helps in delivery.

Habit Forming

No

Therapeutic Class

OXYTOCIC, UTEROTONIC, ECBOLIC

MEM INJECTION 1ML Substitute

Substitutes safety advice
  • Methergin Injection 1's

    14.50per tablet
  • Methygin Injection 1ml

    15.75per tablet
  • Utergin 0.2 Injection 1's

    13.05per tablet
  • Methyler Injection 1 ml

    10.80per tablet
  • Wergomet 0.2mg Injection

    4.38per tablet
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Alcohol

Unsafe

It is not known if alcohol affects MEM INJECTION 1ML. Consult your doctor.

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Pregnancy

Unsafe

MEM INJECTION 1ML is not recommended for use during pregnancy.

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Breast Feeding

Unsafe

It is advised to avoid breastfeeding for at least 12 hours after taking MEM INJECTION 1ML as this medicine may pass into breast milk and can harm a nursing baby.

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Driving

Unsafe

Avoid driving and operating machinery.

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Liver

Safe if prescribed

MEM INJECTION 1ML is not known to show any interaction in liver disease.

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Kidney

Caution

MEM INJECTION 1ML to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose will be adjusted by your doctor.

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Children

Unsafe

MEM INJECTION 1ML is not recommended for children below the age of 18 years. The safety and effectiveness of MEM INJECTION 1ML have not been established in children.

FAQs

MEM INJECTION 1ML is used to prevent and stop heavy bleeding (postpartum-third stage of labour bleeding) after childbirth or after a miscarriage in cesarean section. Besides this, it is also used to improve uterine contraction (antepartum) and produce uterine contraction during the third stage of labor (postpartum).
MEM INJECTION 1ML works by stimulating uterine muscles and increasing the uterus' contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), and increases the contraction, thereby inducing labour pain in pregnant women. As a result, these increased uterine contractions help in the child's delivery and substantially reduce excessive uterine bleeding.
If you have a previous premature delivery or a cesarian section, or cervical surgery, please inform your doctor before starting MEM INJECTION 1ML. Also, mention a detailed medical history to your doctor to avoid any complications.
The most common side effects of MEM INJECTION 1ML include nausea, vomiting, stomach pain, mild headache. You might also feel increased uterine contractions for some time, but these are manageable under medical supervision.
It is suggested to avoid grapefruit and grapefruit juice while taking MEM INJECTION 1ML as it can worsen the side effects of MEM INJECTION 1ML.
It is advised to tell your doctor if you are using antifungal medicine (Fluconazole) or other medicine, including prescription and over-the-counter medicines, vitamins, and herbal products, as taking MEM INJECTION 1ML with some medications may cause serious side effects.

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - MEM0012

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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