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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Methergin Tablet is used to prevent and control postpartum haemorrhage. This medicine contains methylergometrine, which increases the uterus's smooth muscle contractions and thereby controls bleeding after delivery. Some of the side effects include seizures and/or headache, nausea, and vomiting.
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Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Methergin Tablet

Methergin Tablet is used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.

Methergin Tablet contains Methylergometrine, which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Take Methergin Tablet exactly as prescribed by the doctor. In some cases, Methergin Tablet may cause high blood pressure associated with seizures and/or headache, nausea, and vomiting. If the side effects persist or worsen, consult your doctor.

Do not take Methergin Tablet if you are pregnant. Consult your doctor if you are breastfeeding. Methergin Tablet is not recommended for children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Methergin Tablet

Treatment of Postpartum haemorrhage

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Methergin Tablet is indicated in the prevention and control of postpartum haemorrhage. It is used following delivery of the placenta for the routine management of uterine atony (soft and weak uterus after childbirth), subinvolution of the uterus, and haemorrhage. Methergin Tablet contains Methylergometrine, a semi-synthetic ergot alkaloid which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

How Methergin Tablet Works

Methergin Tablet contains Methylergometrine, which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Methergin Tablet

  • Hypertension (high blood pressure) associated with seizures and/or headache
  • Nausea
  • Vomiting

What if I have taken an overdose of Methergin Tablet

Avoid taking more than the prescribed dose of Methergin Tablet as it can cause serious side effects. Overdose of Methergin Tablet include severe headache, severe dizziness, seizures, slow/shallow breathing. Seek immediate medical attention if you observe any of these side effects.

Drug Warnings

Do not take Methergin Tablet if you are allergic to any of its components, if you have high blood pressure, toxaemia (a complication of pregnancy characterised by high blood pressure), or if you are pregnant. Inform your doctor if you have coronary artery disease, sepsis, vascular disease, or liver or kidney impairment. Consult your doctor if you are breastfeeding. The safety and effectiveness of Methergin Tablet in children have not been established. Let your doctor know if you are taking prescription/non-prescription medicines, including herbal products and supplements.

Drug-Drug Interactions

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MethylergometrineKetoconazole
Critical
MethylergometrineRitonavir
Critical

Drug-Drug Interactions

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MethylergometrineKetoconazole
Critical
How does the drug interact with Methergin Tablet 10's:
Using Ketoconazole with Methergin Tablet 10's can increase the concentration of Methergin Tablet 10's, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Methergin Tablet 10's is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineRitonavir
Critical
How does the drug interact with Methergin Tablet 10's:
Taking Methergin Tablet 10's with Ritonavir can significantly increase the blood levels and effects of Methergin Tablet 10's.

How to manage the interaction:
Taking Methergin Tablet 10's with Ritonavir is not recommended, but can be taken together if prescribed by a doctor. In case you experience any side effects like severe abdominal discomfort, nausea, vomiting, tingling or numbness, weakness or pain in the muscles, pale skin, blue or purple discoloration on fingers or toes, tightness or pain in the chest, irregular heartbeat, intense headache, breathing difficulties, confusion, or slurred speech, consult a doctor. Do not discontinue any medications without consulting a doctor.
MethylergometrineVoriconazole
Critical
How does the drug interact with Methergin Tablet 10's:
Coadministration of Methergin Tablet 10's with Voriconazole may increase the blood level of Methergin Tablet 10's.

How to manage the interaction:
Although Methergin Tablet 10's with Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineClarithromycin
Critical
How does the drug interact with Methergin Tablet 10's:
When Methergin Tablet 10's is taken with Clarithromycin, the amount of Methergin Tablet 10's in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Clarithromycin with Methergin Tablet 10's is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
MethylergometrineSumatriptan
Critical
How does the drug interact with Methergin Tablet 10's:
Coadministration of Sumatriptan with Methergin Tablet 10's can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Sumatriptan with Methergin Tablet 10's together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MethylergometrineKetoconazole
Critical
How does the drug interact with Methergin Tablet 10's:
Using Ketoconazole with Methergin Tablet 10's can increase the concentration of Methergin Tablet 10's, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Methergin Tablet 10's can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineGlyceryl trinitrate
Critical
How does the drug interact with Methergin Tablet 10's:
Coadministration of Methergin Tablet 10's with Glyceryl trinitrate can increase the levels and side effects of Methergin Tablet 10's.

How to manage the interaction:
Taking Methergin Tablet 10's with Glyceryl trinitrate is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
MethylergometrineItraconazole
Critical
How does the drug interact with Methergin Tablet 10's:
Co-administration of Methergin Tablet 10's and Itraconazole may increase the blood levels of Methergin Tablet 10's.

How to manage the interaction:
Methergin Tablet 10's and itraconazole may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
MethylergometrineEphedrine
Severe
How does the drug interact with Methergin Tablet 10's:
Taking Ephedrine with Methergin Tablet 10's may lead to an increase in the risk of high blood pressure.

How to manage the interaction:
Although taking Ephedrine with Methergin Tablet 10's may lead to an interaction, it can be taken if prescribed by the doctor. It is advised to maintain your blood pressure. Do not discontinue any medications without a doctor's advice.
MethylergometrinePhenylephrine
Severe
How does the drug interact with Methergin Tablet 10's:
Taking Phenylephrine with Methergin Tablet 10's can led to side effects like increased blood pressure.

How to manage the interaction:
Taking Phenylephrine with Methergin Tablet 10's can lead to an interaction but can be taken if prescribed by the doctor. It is advised to monitor your blood pressure regularly. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of Methergin Tablet 10's with Grapefruit and Grapefruit may lead to an increase in the effectiveness of Methergin Tablet 10's. Avoid or limit grapefruit and grapefruit juice consumption with Methergin Tablet 10's. This can increase the risk or severity of side effects.

Diet & Lifestyle Advise

  • Include high-fibre foods such as fruits and whole grains.
  • Drink plenty of fluids such as water, fruit juices, and milk.
  • Limit processed/packaged foods, high salt/sugary foods and saturated fats.
  • Get plenty of rest.
  • Eat healthy meals and exercise appropriately.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Methergin Tablet Substitute

Substitutes safety advice
  • Ergostat Tablet 10's

    by AYUR

    7.49per tablet
  • Methygin Tablet 10's

    9.00per tablet
  • UTERGIN 0.125MG TABLET

    78.12per tablet
  • Utergin Tablet 10's

    9.00per tablet
  • Ergolin 0.125 Tablet 10's

    7.81per tablet
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Alcohol

Caution

It is not known if alcohol affects Methergin Tablet . Please consult your doctor.

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Pregnancy

Unsafe

Methergin Tablet is not recommended for use during pregnancy.

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Breast Feeding

Caution

Methergin Tablet passes into breastmilk. Avoid breastfeeding during treatment with Methergin Tablet and for 12 hours after the last dose. Please consult your doctor if you have any concerns.

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Driving

Caution

It is not known if Methergin Tablet affects your ability to drive.

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Liver

Caution

Caution should be exercised while using Methergin Tablet in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Caution should be exercised while using Methergin Tablet in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Methergin Tablet is not recommended for children as safety and effectiveness have not been established.

FAQs

Methergin Tablet is used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.
Methergin Tablet works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.
Methergin Tablet is not recommended for use in people with high blood pressure. Consult your doctor if you have hypertension.
Methergin Tablet may cause nausea or vomiting as a side effect. It is not necessary for everyone taking Methergin Tablet to experience this side effect. However, if the condition persists or worsens, consult your doctor.
Methergin Tablet may be indicated in the management of uterine atony. Uterine atony refers to a weak and soft uterus after childbirth.
Yes, Methergin Tablet may cause decreased milk production if taken by lactating mothers after childbirth. It is recommended to avoid breastfeeding while taking Methergin Tablet for at least 12 hours after your last dose. Consult the doctor if you have any concerns.
Methergin Tablet should not be used to stop uterine bleeding after child birth if the patient has high blood pressure as it may worsen hypertension. Consult the doctor if you have any concerns.
No, Methergin Tablet should not be used to stop menstrual bleeding as it is used to manage and prevent excessive bleeding after childbirth (postpartum haemorrhage).
Methergin Tablet should be taken with or without food as advised by the doctor based on your medical condition.
You should not take Methergin Tablet if you are allergic to any of its ingredients. It should not be taken by individuals with high blood pressure (hypertension), or toxaemia (an abnormal condition associated with the presence of toxic substances in the bloodstream) during pregnancy.
No, breastfeeding should be avoided during treatment with Methergin Tablet and for at least 12 hours after the final dose. Consult the doctor if you have any concerns.
Yes, Methergin Tablet may cause an increase in blood pressure as a common side effect. Consult the doctor before taking Methergin Tablet if you have high blood pressure.
Patients with heart disease may have an increased risk of myocardial ischemia and infarction due to methylergonovine-induced vasospasm. Consult the doctor if you have any heart problems.
The side effects of Methergin Tablet include nausea, vomiting, headache, and hypertension (increased blood pressure) associated with seizures. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - MET0067

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