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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Mergox 0.125mg Tablet is used to prevent and control postpartum haemorrhage. This medicine contains methylergometrine, which increases the uterus's smooth muscle contractions and thereby controls bleeding after delivery. Some of the side effects include seizures and/or headache, nausea, and vomiting.
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Mergox 0.125mg Tablet

Mergox 0.125mg Tablet is used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.

Mergox 0.125mg Tablet contains Methylergometrine, which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Take Mergox 0.125mg Tablet exactly as prescribed by the doctor. In some cases, Mergox 0.125mg Tablet may cause high blood pressure associated with seizures and/or headache, nausea, and vomiting. If the side effects persist or worsen, consult your doctor.

Do not take Mergox 0.125mg Tablet if you are pregnant. Consult your doctor if you are breastfeeding. Mergox 0.125mg Tablet is not recommended for children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Mergox 0.125mg Tablet

Treatment of Postpartum haemorrhage

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Mergox 0.125mg Tablet is indicated in the prevention and control of postpartum haemorrhage. It is used following delivery of the placenta for the routine management of uterine atony (soft and weak uterus after childbirth), subinvolution of the uterus, and haemorrhage. Mergox 0.125mg Tablet contains Methylergometrine, a semi-synthetic ergot alkaloid which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

How Mergox 0.125mg Tablet Works

Mergox 0.125mg Tablet contains Methylergometrine, which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mergox 0.125mg Tablet

  • Hypertension (high blood pressure) associated with seizures and/or headache
  • Nausea
  • Vomiting

What if I have taken an overdose of Mergox 0.125mg Tablet

Avoid taking more than the prescribed dose of Mergox 0.125mg Tablet as it can cause serious side effects. Overdose of Mergox 0.125mg Tablet include severe headache, severe dizziness, seizures, slow/shallow breathing. Seek immediate medical attention if you observe any of these side effects.

Drug Warnings

Do not take Mergox 0.125mg Tablet if you are allergic to any of its components, if you have high blood pressure, toxaemia (a complication of pregnancy characterised by high blood pressure), or if you are pregnant. Inform your doctor if you have coronary artery disease, sepsis, vascular disease, or liver or kidney impairment. Consult your doctor if you are breastfeeding. The safety and effectiveness of Mergox 0.125mg Tablet in children have not been established. Let your doctor know if you are taking prescription/non-prescription medicines, including herbal products and supplements.

Drug-Drug Interactions

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MethylergometrineVoriconazole
Critical
MethylergometrineKetoconazole
Critical

Drug-Drug Interactions

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MethylergometrineVoriconazole
Critical
How does the drug interact with Mergox 0.125mg Tablet:
Coadministration of Mergox 0.125mg Tablet with Voriconazole may increase the blood level of Mergox 0.125mg Tablet.

How to manage the interaction:
Although Mergox 0.125mg Tablet with Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineKetoconazole
Critical
How does the drug interact with Mergox 0.125mg Tablet:
Using Ketoconazole with Mergox 0.125mg Tablet can increase the concentration of Mergox 0.125mg Tablet, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Mergox 0.125mg Tablet can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineSumatriptan
Critical
How does the drug interact with Mergox 0.125mg Tablet:
Coadministration of Sumatriptan with Mergox 0.125mg Tablet can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Sumatriptan with Mergox 0.125mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MethylergometrineClarithromycin
Critical
How does the drug interact with Mergox 0.125mg Tablet:
When Mergox 0.125mg Tablet is taken with Clarithromycin, the amount of Mergox 0.125mg Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Clarithromycin with Mergox 0.125mg Tablet is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
MethylergometrineItraconazole
Critical
How does the drug interact with Mergox 0.125mg Tablet:
Co-administration of Mergox 0.125mg Tablet and Itraconazole may increase the blood levels of Mergox 0.125mg Tablet.

How to manage the interaction:
Mergox 0.125mg Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
MethylergometrineGlyceryl trinitrate
Critical
How does the drug interact with Mergox 0.125mg Tablet:
Coadministration of Mergox 0.125mg Tablet with Glyceryl trinitrate can increase the levels and side effects of Mergox 0.125mg Tablet.

How to manage the interaction:
Taking Mergox 0.125mg Tablet with Glyceryl trinitrate is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
MethylergometrineKetoconazole
Critical
How does the drug interact with Mergox 0.125mg Tablet:
Using Ketoconazole with Mergox 0.125mg Tablet can increase the concentration of Mergox 0.125mg Tablet, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Mergox 0.125mg Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineRitonavir
Critical
How does the drug interact with Mergox 0.125mg Tablet:
Taking Mergox 0.125mg Tablet with Ritonavir can significantly increase the blood levels and effects of Mergox 0.125mg Tablet.

How to manage the interaction:
Taking Mergox 0.125mg Tablet with Ritonavir is not recommended, but can be taken together if prescribed by a doctor. In case you experience any side effects like severe abdominal discomfort, nausea, vomiting, tingling or numbness, weakness or pain in the muscles, pale skin, blue or purple discoloration on fingers or toes, tightness or pain in the chest, irregular heartbeat, intense headache, breathing difficulties, confusion, or slurred speech, consult a doctor. Do not discontinue any medications without consulting a doctor.
MethylergometrineEphedrine
Severe
How does the drug interact with Mergox 0.125mg Tablet:
Taking Ephedrine with Mergox 0.125mg Tablet may lead to an increase in the risk of high blood pressure.

How to manage the interaction:
Although taking Ephedrine with Mergox 0.125mg Tablet may lead to an interaction, it can be taken if prescribed by the doctor. It is advised to maintain your blood pressure. Do not discontinue any medications without a doctor's advice.
MethylergometrinePhenylephrine
Severe
How does the drug interact with Mergox 0.125mg Tablet:
Taking Phenylephrine with Mergox 0.125mg Tablet can led to side effects like increased blood pressure.

How to manage the interaction:
Taking Phenylephrine with Mergox 0.125mg Tablet can lead to an interaction but can be taken if prescribed by the doctor. It is advised to monitor your blood pressure regularly. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of Mergox 0.125mg Tablet with Grapefruit and Grapefruit may lead to an increase in the effectiveness of Mergox 0.125mg Tablet. Avoid or limit grapefruit and grapefruit juice consumption with Mergox 0.125mg Tablet. This can increase the risk or severity of side effects.

Diet & Lifestyle Advise

  • Include high-fibre foods such as fruits and whole grains.
  • Drink plenty of fluids such as water, fruit juices, and milk.
  • Limit processed/packaged foods, high salt/sugary foods and saturated fats.
  • Get plenty of rest.
  • Eat healthy meals and exercise appropriately.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Mergox 0.125mg Tablet Substitute

Substitutes safety advice
  • Methergin Tablet 10's

    8.80per tablet
  • Ergostat Tablet 10's

    by AYUR

    7.49per tablet
  • Methygin Tablet 10's

    9.00per tablet
  • UTERGIN 0.125MG TABLET

    78.12per tablet
  • Utergin Tablet 10's

    9.00per tablet
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Alcohol

Caution

It is not known if alcohol affects Mergox 0.125mg Tablet. Please consult your doctor.

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Pregnancy

Unsafe

Mergox 0.125mg Tablet is not recommended for use during pregnancy.

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Breast Feeding

Caution

Mergox 0.125mg Tablet passes into breastmilk. Avoid breastfeeding during treatment with Mergox 0.125mg Tablet and for 12 hours after the last dose. Please consult your doctor if you have any concerns.

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Driving

Caution

It is not known if Mergox 0.125mg Tablet affects your ability to drive.

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Liver

Caution

Caution should be exercised while using Mergox 0.125mg Tablet in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Caution should be exercised while using Mergox 0.125mg Tablet in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Mergox 0.125mg Tablet is not recommended for children as safety and effectiveness have not been established.

FAQs

Mergox 0.125mg Tablet is used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.
Mergox 0.125mg Tablet works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.
Mergox 0.125mg Tablet is not recommended for use in people with high blood pressure. Consult your doctor if you have hypertension.
Mergox 0.125mg Tablet may cause nausea or vomiting as a side effect. It is not necessary for everyone taking Mergox 0.125mg Tablet to experience this side effect. However, if the condition persists or worsens, consult your doctor.
Mergox 0.125mg Tablet may be indicated in the management of uterine atony. Uterine atony refers to a weak and soft uterus after childbirth.
Yes, Mergox 0.125mg Tablet may cause decreased milk production if taken by lactating mothers after childbirth. It is recommended to avoid breastfeeding while taking Mergox 0.125mg Tablet for at least 12 hours after your last dose. Consult the doctor if you have any concerns.
Mergox 0.125mg Tablet should not be used to stop uterine bleeding after child birth if the patient has high blood pressure as it may worsen hypertension. Consult the doctor if you have any concerns.
No, Mergox 0.125mg Tablet should not be used to stop menstrual bleeding as it is used to manage and prevent excessive bleeding after childbirth (postpartum haemorrhage).
Mergox 0.125mg Tablet should be taken with or without food as advised by the doctor based on your medical condition.
You should not take Mergox 0.125mg Tablet if you are allergic to any of its ingredients. It should not be taken by individuals with high blood pressure (hypertension), or toxaemia (an abnormal condition associated with the presence of toxic substances in the bloodstream) during pregnancy.
No, breastfeeding should be avoided during treatment with Mergox 0.125mg Tablet and for at least 12 hours after the final dose. Consult the doctor if you have any concerns.
Yes, Mergox 0.125mg Tablet may cause an increase in blood pressure as a common side effect. Consult the doctor before taking Mergox 0.125mg Tablet if you have high blood pressure.
Patients with heart disease may have an increased risk of myocardial ischemia and infarction due to methylergonovine-induced vasospasm. Consult the doctor if you have any heart problems.
The side effects of Mergox 0.125mg Tablet include nausea, vomiting, headache, and hypertension (increased blood pressure) associated with seizures. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India
Other Info - ME51231

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