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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Meriflox 400mg Tablet is used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation) and gonorrhoea (sexually transmitted disease). Additionally, it is used to treat infections of the stomach and intestine like traveller's diarrhoea. It contains Norfloxacin, which kills the bacteria and treats bacterial infections. In some cases, it may cause common side effects such as abdominal cramps, nausea, headache, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

NORFLOXACIN-400MG

Manufacturer/Marketer :

Wockhardt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Meriflox 400mg Tablet

Meriflox 400mg Tablet belongs to the group of quinolones antibiotics used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation) and gonorrhoea (sexually transmitted disease). Additionally, Meriflox 400mg Tablet is used to treat infections of the stomach and intestine like traveller’s diarrhoea. 

Meriflox 400mg Tablet contains Norfloxacin which inhibits the synthesis of an enzyme called DNA gyrase. Thereby kills the bacteria and treats bacterial infections. Meriflox 400mg Tablet has a broad spectrum antibacterial activity against gram-positive and gram-negative aerobic bacteria.

Take Meriflox 400mg Tablet as prescribed. In some cases, Meriflox 400mg Tablet may cause common side-effects such as abdominal cramps, nausea, headache, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side-effects persist or worsen.

Inform your doctor if you experience pain in tendons, swelling, or inflammation as Meriflox 400mg Tablet is associated with an increased risk of tendon rupture and tendonitis; this risk is higher in patients older than 60years, in people taking steroids, or who have had kidney, heart or lung transplant. Meriflox 400mg Tablet may cause dizziness and light-headedness, so drive only if you are alert. Avoid alcohol consumption while taking Meriflox 400mg Tablet as it may cause increased dizziness.

Uses of Meriflox 400mg Tablet

Treatment of Bacterial infections, Traveller's diarrhoea

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush or chew the tablet/capsule. Take it on an empty stomach, i.e., one hour before food or two hours after food. Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup provided by the pack.

Medicinal Benefits

Meriflox 400mg Tablet belongs to the group of medicines called quinolones antibiotics used to treat bacterial infections of the prostate, urinary tract and gonorrhoea (sexually transmitted disease). Additionally, Meriflox 400mg Tablet is also used to treat traveller’s diarrhoea. Meriflox 400mg Tablet is bactericidal in nature. It works by inhibiting the synthesis of bacterial DNA gyrase; this prevents the bacteria from repairing and multiplying. Thereby, kills the bacteria and treats infections. Meriflox 400mg Tablet is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.

How Meriflox 400mg Tablet Works

Meriflox 400mg Tablet contains Norfloxacin which inhibits the synthesis of an enzyme called DNA gyrase. Thereby kills the bacteria and treats bacterial infections. Meriflox 400mg Tablet has a broad spectrum antibacterial activity against gram-positive and gram-negative aerobic bacteria.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Meriflox 400mg Tablet

  • Nausea
  • Heartburn
  • Headache
  • Dizziness
  • Abdominal cramps

What if I have taken an overdose of Meriflox 400mg Tablet

Do not take more than the prescribed dose of Meriflox 400mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Meriflox 400mg Tablet if you are allergic to any of its contents; if you had swelling or tearing of tendons while taking quinolone antibiotics. Meriflox 400mg Tablet is associated with an increased risk of tendon rupture and tendonitis in all age groups; this risk is higher in patients older than 60 years, people taking corticosteroids, who have had kidney, heart or lung transplants. Consult your doctor immediately if you experience tendon pain, swelling or inflammation while taking Meriflox 400mg Tablet. Do not take Meriflox 400mg Tablet if you have myasthenia gravis, as it may cause increased muscle weakness. Talk to your doctor if you have epilepsy, low levels of potassium, nervous or muscle problems, head injury or brain tumour, diabetes,  rheumatoid arthritis, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Meriflox 400mg Tablet as it may cause increased dizziness. Meriflox 400mg Tablet may cause dizziness and vision problems, so be cautious while driving.

Drug-Drug Interactions

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NorfloxacinBepridil
Critical
NorfloxacinMesoridazine
Critical

Drug-Drug Interactions

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NorfloxacinBepridil
Critical
How does the drug interact with Meriflox 400mg Tablet:
Using bepridil together with Meriflox 400mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Meriflox 400mg Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
NorfloxacinMesoridazine
Critical
How does the drug interact with Meriflox 400mg Tablet:
Using Mesoridazine together with Meriflox 400mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Meriflox 400mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
NorfloxacinAmiodarone
Critical
How does the drug interact with Meriflox 400mg Tablet:
The combination of Amiodarone and Meriflox 400mg Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Meriflox 400mg Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
NorfloxacinSotalol
Critical
How does the drug interact with Meriflox 400mg Tablet:
Coadministration of Meriflox 400mg Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Meriflox 400mg Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinDisopyramide
Critical
How does the drug interact with Meriflox 400mg Tablet:
Coadministration of Meriflox 400mg Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Meriflox 400mg Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinCisapride
Critical
How does the drug interact with Meriflox 400mg Tablet:
Coadministration of Meriflox 400mg Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Meriflox 400mg Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinDofetilide
Severe
How does the drug interact with Meriflox 400mg Tablet:
Using Dofetilide together with Meriflox 400mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Meriflox 400mg Tablet with Dofetilide can result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like an irregular heart rhythm, dizziness, fainting, or difficulty breathing, it is important to contact a doctor right away." Do not discontinue any medications without consulting a doctor.
NorfloxacinPrednisolone
Severe
How does the drug interact with Meriflox 400mg Tablet:
Co-administration of Meriflox 400mg Tablet may cause tendinitis (inflammation of a tissue that attaches muscle to bone) and tendon rupture, and the risk may be increased when combined with Prednisolone. People over the age of 60 and people who have had a kidney, heart, or lung transplant may be especially at risk.

How to manage the interaction:
Although there is an interaction, Prednisolone can be taken with Meriflox 400mg Tablet if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb, stop taking Meriflox 400mg Tablet and consult a doctor. Do not discontinue any medications without consulting a doctor.
NorfloxacinGlimepiride
Severe
How does the drug interact with Meriflox 400mg Tablet:
Co-administration of Meriflox 400mg Tablet with Glimepiride may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Glimepiride can be taken with Meriflox 400mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
NorfloxacinIloperidone
Severe
How does the drug interact with Meriflox 400mg Tablet:
Coadministration of Meriflox 400mg Tablet with Iloperidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Meriflox 400mg Tablet with Iloperidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu, Orange Juice

How to manage the interaction:
Consuming dairy products, cereal, or orange juice with Meriflox 400mg Tablet can interfere with its absorption and reduce its levels in the blood and urinary tract. Using caffeine together with Meriflox 400mg Tablet may increase the effects of caffeine. Meriflox 400mg Tablet dose should be taken at least one hour before or two hours after consuming dairy products, cereal, or orange juice. Avoid taking caffeine with Meriflox 400mg Tablet. Contact a doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate.

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

  • Avoid foods rich in calcium, grapefruit and grapefruit juice, as they might hinder the absorption of antibiotics.

  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Meriflox 400mg Tablet Substitute

Substitutes safety advice
  • Norflox 400 Tablet 10's

    7.70per tablet
  • Norflokem 400Mg Tablet

    by AYUR

    7.56per tablet
  • Norcin 400 mg Tablet 10's

    4.23per tablet
  • NORFLOXACIN 400MG TABLET

    4.23per tablet
  • N-Flox Tablet 10's

    6.93per tablet
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Alcohol

Unsafe

Avoid consuming alcohol while taking Meriflox 400mg Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Meriflox 400mg Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant, your doctor will prescribe Meriflox 400mg Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown if Meriflox 400mg Tablet passes into breastmilk. Consult your doctor if you are breastfeeding.

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Driving

Caution

Meriflox 400mg Tablet may cause dizziness and light-headedness. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Unsafe

Meriflox 400mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.

FAQs

Meriflox 400mg Tablet is used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation) and gonorrhoea (sexually transmitted disease). Additionally, Meriflox 400mg Tablet is used to treat infections of the stomach and intestine like traveller’s diarrhoea.
Meriflox 400mg Tablet works by inhibiting the synthesis of bacterial DNA gyrase; this prevents the bacteria from repairing and multiplying. Thereby, helps in treating the infections.
Meriflox 400mg Tablet may cause photosensitivity (sensitivity to sunlight) and can make you sunburn easily. Avoid prolonged exposure to sunlight or tanning beds. Always wear protective clothing and sunscreen with SPF 30 or higher before going out.
It is recommended to complete the course of Meriflox 400mg Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection. To treat your condition effectually, continue taking Meriflox 400mg Tablet for as long as your doctor has prescribed it.
Avoid consuming dairy products such as milk and yoghurt along with Meriflox 400mg Tablet as they may decrease the effectiveness of Meriflox 400mg Tablet.
Do not take Meriflox 400mg Tablet on your own, as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.
Maintain a minimum gap of two hours between Meriflox 400mg Tablet and antacid, anti-ulcer (sucralfate), anti-HIV (didanosine), vitamin and mineral medicines. However, consult your doctor before taking other medicines with Meriflox 400mg Tablet.
Consult your doctor before taking Meriflox 400mg Tablet if you have diabetes, as Meriflox 400mg Tablet may cause hypoglycaemia (low blood sugar levels). Regularly monitor blood sugar levels while taking Meriflox 400mg Tablet to avoid hypoglycaemic events.
Meriflox 400mg Tablet may cause changes in liver function tests and prothrombin time (time taken for blood clotting). Inform the person doing the tests that you are taking Meriflox 400mg Tablet.
If you're feeling better, don't stop taking the medicine! Instead, report your progress to your doctor and follow their advice. Remember, finishing the entire course of therapy is crucial to ensuring the infection is fully gone and doesn't come back. Your doctor will guide you on what to do next, so check in with them.
Common side-effects of Meriflox 400mg Tablet may include abdominal cramps, nausea, headache, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side-effects persist or worsen.
I am a pregnant woman. Is it safe to use Meriflox 400mg Tablet?

Country of origin

India
Other Info - ME37346

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