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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 23, 2024 | 4:54 PM IST
Norflox 400 Tablet is used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation) and gonorrhoea (sexually transmitted disease). Additionally, it is used to treat infections of the stomach and intestine like traveller's diarrhoea. It contains Norfloxacin, which kills the bacteria and treats bacterial infections. In some cases, it may cause common side effects such as abdominal cramps, nausea, headache, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Cipla Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Norflox 400 Tablet

Norflox 400 Tablet belongs to the group of quinolones antibiotics used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation) and gonorrhoea (sexually transmitted disease). Additionally, Norflox 400 Tablet is used to treat infections of the stomach and intestine like traveller’s diarrhoea. 

Norflox 400 Tablet contains Norfloxacin which inhibits the synthesis of an enzyme called DNA gyrase. Thereby kills the bacteria and treats bacterial infections. Norflox 400 Tablet has a broad spectrum antibacterial activity against gram-positive and gram-negative aerobic bacteria.

Take Norflox 400 Tablet as prescribed. In some cases, Norflox 400 Tablet may cause common side-effects such as abdominal cramps, nausea, headache, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side-effects persist or worsen.

Inform your doctor if you experience pain in tendons, swelling, or inflammation as Norflox 400 Tablet is associated with an increased risk of tendon rupture and tendonitis; this risk is higher in patients older than 60years, in people taking steroids, or who have had kidney, heart or lung transplant. Norflox 400 Tablet may cause dizziness and light-headedness, so drive only if you are alert. Avoid alcohol consumption while taking Norflox 400 Tablet as it may cause increased dizziness.

Uses of Norflox 400 Tablet

Treatment of Bacterial infections, Traveller's diarrhoea

Medicinal Benefits

Norflox 400 Tablet belongs to the group of medicines called quinolones antibiotics used to treat bacterial infections of the prostate, urinary tract and gonorrhoea (sexually transmitted disease). Additionally, Norflox 400 Tablet is also used to treat traveller’s diarrhoea. Norflox 400 Tablet is bactericidal in nature. It works by inhibiting the synthesis of bacterial DNA gyrase; this prevents the bacteria from repairing and multiplying. Thereby, kills the bacteria and treats infections. Norflox 400 Tablet is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush or chew the tablet/capsule. Take it on an empty stomach, i.e., one hour before food or two hours after food. Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Norflox 400 Tablet

  • Nausea
  • Heartburn
  • Headache
  • Dizziness
  • Abdominal cramps

Drug Warnings

Do not take Norflox 400 Tablet if you are allergic to any of its contents; if you had swelling or tearing of tendons while taking quinolone antibiotics. Norflox 400 Tablet is associated with an increased risk of tendon rupture and tendonitis in all age groups; this risk is higher in patients older than 60 years, people taking corticosteroids, who have had kidney, heart or lung transplants. Consult your doctor immediately if you experience tendon pain, swelling or inflammation while taking Norflox 400 Tablet . Do not take Norflox 400 Tablet if you have myasthenia gravis, as it may cause increased muscle weakness. Talk to your doctor if you have epilepsy, low levels of potassium, nervous or muscle problems, head injury or brain tumour, diabetes,  rheumatoid arthritis, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Norflox 400 Tablet as it may cause increased dizziness. Norflox 400 Tablet may cause dizziness and vision problems, so be cautious while driving.

Drug Interactions

Drug-Drug Interactions: Norflox 400 Tablet may interact with pain killers (aspirin, ibuprofen), anti-coagulant/blood thinner (warfarin), anti-gout (probenecid), antibiotic (azithromycin, sulfamethoxazole, trimethoprim, metronidazole, nitrofurantoin, erythromycin), and calcium supplements (calcium/vitamin D).

Drug-Food Interactions: Avoid dairy products such as milk and yoghurt while taking Norflox 400 Tablet as they might decrease the effectiveness of Norflox 400 Tablet . Avoid consuming caffeine products along with Norflox 400 Tablet as it might increase the effects of caffeine.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), tendonitis (inflammation in tendons), CNS disorders, myasthenia gravis (neuromuscular disease), peripheral neuropathy (nerve pain), crystalluria (cloudy urine), diabetes, kidney, liver or heart problems.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • WARFARIN
  • PROBENECID
  • AZITHROMYCIN
  • TRIMETHOPRIM+SULFAMETHOXAZOLE
  • METRONIDAZOLE
  • NITROFURANTOIN
  • ERYTHROMYCIN
  • CALCIUM CARBONATE+CHOLECALCIFEROL

Habit Forming

No

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

  • Avoid foods rich in calcium, grapefruit and grapefruit juice, as they might hinder the absorption of antibiotics.

  • Avoid consumption of alcohol and usage of tobacco.

Special Advise

Norflox 400 Tablet may cause changes in liver function tests and prothrombin time (time taken for blood clotting). Inform the person doing the tests that you are taking Norflox 400 Tablet .

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. Symptoms include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicines are more prone to bacterial infection.

Traveller’s diarrhoea: It is a digestive tract disorder that commonly occurs due to the consumption of contaminated food and water that the body is not familiar with. Symptoms include gas, bloating, abdominal cramps, nausea, vomiting, and loose stools.

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Alcohol

Unsafe

Avoid consuming alcohol while taking Norflox 400 Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Norflox 400 Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant, your doctor will prescribe Norflox 400 Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown if Norflox 400 Tablet passes into breastmilk. Consult your doctor if you are breastfeeding.

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Driving

Caution

Norflox 400 Tablet may cause dizziness and light-headedness. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Unsafe

Norflox 400 Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - NOR0008

Author Details

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FAQs

Norflox 400 Tablet is used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation) and gonorrhoea (sexually transmitted disease). Additionally, Norflox 400 Tablet is used to treat infections of the stomach and intestine like traveller’s diarrhoea.
Norflox 400 Tablet works by inhibiting the synthesis of bacterial DNA gyrase; this prevents the bacteria from repairing and multiplying. Thereby, helps in treating the infections.
Norflox 400 Tablet may cause photosensitivity (sensitivity to sunlight) and can make you sunburn easily. Avoid prolonged exposure to sunlight or tanning beds. Always wear protective clothing and sunscreen with SPF 30 or higher before going out.
It is recommended to complete the course of Norflox 400 Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection. To treat your condition effectually, continue taking Norflox 400 Tablet for as long as your doctor has prescribed it.
Avoid consuming dairy products such as milk and yoghurt along with Norflox 400 Tablet as they may decrease the effectiveness of Norflox 400 Tablet .
Do not take Norflox 400 Tablet on your own, as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.
Maintain a minimum gap of two hours between Norflox 400 Tablet and antacid, anti-ulcer (sucralfate), anti-HIV (didanosine), vitamin and mineral medicines. However, consult your doctor before taking other medicines with Norflox 400 Tablet .
Consult your doctor before taking Norflox 400 Tablet if you have diabetes, as Norflox 400 Tablet may cause hypoglycaemia (low blood sugar levels). Regularly monitor blood sugar levels while taking Norflox 400 Tablet to avoid hypoglycaemic events.
Norflox 400 Tablet may cause changes in liver function tests and prothrombin time (time taken for blood clotting). Inform the person doing the tests that you are taking Norflox 400 Tablet .
If you're feeling better, don't stop taking the medicine! Instead, report your progress to your doctor and follow their advice. Remember, finishing the entire course of therapy is crucial to ensuring the infection is fully gone and doesn't come back. Your doctor will guide you on what to do next, so check in with them.
Common side-effects of Norflox 400 Tablet may include abdominal cramps, nausea, headache, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side-effects persist or worsen.
I am a pregnant woman. Is it safe to use Norflox 400 Tablet ?

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