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  3. Mendate 5 Tablet 10's

Mendate 5 Tablet 10's, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Mendate 5 Tablet 10's is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

NORETHISTERONE-5MG

Manufacturer/Marketer :

Koye Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Mendate 5 Tablet 10's

Mendate 5 Tablet 10's belongs to the class of medicines called progestogens used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Mendate 5 Tablet 10's may be used in the treatment of breast cancer. Endometriosis is a disorder in which the uterus's tissue lining (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain.

Mendate 5 Tablet 10's contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Take Mendate 5 Tablet 10's as prescribed by your doctor. You are advised to take Mendate 5 Tablet 10's for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhoea, headache, breast pain, and tenderness. Most of these side effects of Mendate 5 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Mendate 5 Tablet 10's or any other medicines, please tell your doctor. Mendate 5 Tablet 10's is not recommended for pregnant women as it may harm the unborn baby. If you are breastfeeding, consult a doctor before taking Mendate 5 Tablet 10's. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Mendate 5 Tablet 10's. You are advised to stop smoking while taking Mendate 5 Tablet 10's as it may increase the risk of adverse effects.

Uses of Mendate 5 Tablet 10's

Mendate 5 Tablet 10's is used to treat endometriosis. The detailed uses of Mendate 5 Tablet 10's are as follows:
•Menstrual Cycle Regulation: Mendate 5 Tablet 10's is commonly used to regulate irregular menstrual cycles or to induce menstruation in women experiencing amenorrhea (absence of periods).
•Management of Endometriosis: Mendate 5 Tablet 10's is also effective in managing endometriosis, a condition where uterine-like tissue grows outside the uterus, leading to pain and irregular bleeding.
•Support in Hormone Replacement Therapy: In postmenopausal women, Mendate 5 Tablet 10's is often combined with estrogen therapy to prevent endometrial hyperplasia (thickening of the uterine lining), which can result from estrogen use alone.
•Relieve Menstrual problems: Mendate 5 Tablet 10's is sometimes prescribed to alleviate symptoms of premenstrual syndrome (PMS) and to provide relief from excessive bleeding or pain during menstruation.

Directions for Use

Take Mendate 5 Tablet 10's with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Mendate 5 Tablet 10's contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps treat menstrual disorders.

How Mendate 5 Tablet 10's Works

Mendate 5 Tablet 10's contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mendate 5 Tablet 10's

  • Unusual vaginal bleeding or spotting
  • Dizziness
  • Dry mouth
  • Constipation
  • Nausea
  • Diarrhea
  • Headache
  • Breast pain and tenderness

What if I have taken an overdose of Mendate 5 Tablet 10's

Take Mendate 5 Tablet 10's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, breast enlargement and vaginal bleeding. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Mendate 5 Tablet 10's or any other medicines, please tell your doctor. Mendate 5 Tablet 10's is not recommended for pregnant women as it may harm an unborn baby. If you are breastfeeding, consult a doctor before taking Mendate 5 Tablet 10's. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Mendate 5 Tablet 10's. You are advised to stop smoking while taking Mendate 5 Tablet 10's as it may increase the risk of adverse effects. If you are about to undergo any surgery, please inform your doctor that you are taking Mendate 5 Tablet 10's as it may increase the effect of certain anesthetics. If you experience sudden shortness of breath, rapid heartbeat, sudden, severe, sharp pain in the chest, or cough up blood, stop taking Mendate 5 Tablet 10's and consult a doctor immediately as these might be signs of a blood clot in the lungs.

Drug-Drug Interactions

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NorethisteroneRifapentine
Severe
NorethisteroneDabrafenib
Severe

Drug-Drug Interactions

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NorethisteroneRifapentine
Severe
How does the drug interact with Mendate 5 Tablet:
Combining Rifapentine and norethindrone reduces the blood levels and effects of norethindrone and increases the risk of bleeding and unintended pregnancy.

How to manage the interaction:
Although there is a possible interaction between Mendate 5 Tablet and Rifapentine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like unexpected bleeding, abnormal bleeding, it's important to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
NorethisteroneDabrafenib
Severe
How does the drug interact with Mendate 5 Tablet:
Coadministration of Mendate 5 Tablet with Dabrafenib can reduce the metabolism and decrease the levels of Mendate 5 Tablet in the body.

How to manage the interaction:
Taking Mendate 5 Tablet with Dabrafenib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of hot flashes, vaginal dryness, or abnormal bleeding, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneBoceprevir
Severe
How does the drug interact with Mendate 5 Tablet:
Using Boceprevir and Mendate 5 Tablet together can reduce the blood levels and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Boceprevir with Mendate 5 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, abnormal bleeding, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneBosentan
Severe
How does the drug interact with Mendate 5 Tablet:
Co-administration of Mendate 5 Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Mendate 5 Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
NorethisteroneAcitretin
Severe
How does the drug interact with Mendate 5 Tablet:
Coadministration of Acitretin with Mendate 5 Tablet may interfere with the contraceptive effect of Mendate 5 Tablet.

How to manage the interaction:
Acitretin and Mendate 5 Tablet should be used together only if prescribed by your doctor. Use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy.
NorethisteroneCarbamazepine
Severe
How does the drug interact with Mendate 5 Tablet:
Taking carbamazepine and Mendate 5 Tablet may possibly reduce the effects of Mendate 5 Tablet which may result in higher risk of breakthrough bleeding and unexpected pregnancy.

How to manage the interaction:
Although taking carbamazepine and Mendate 5 Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Contact your doctor if you experience hot flashes, vaginal dryness, or uncontrolled bleeding. Do not discontinue any medications without consulting a doctor.
NorethisteroneBexarotene
Severe
How does the drug interact with Mendate 5 Tablet:
Coadministration of Bexarotene and Mendate 5 Tablet together can decrease the effectiveness of norethindrone and increase the risk of unintended pregnancy.

How to manage the interaction:
Combining Bexarotene with Mendate 5 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneFosamprenavir
Severe
How does the drug interact with Mendate 5 Tablet:
Using norethindrone together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Taking Mendate 5 Tablet with Fosamprenavir together can result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing any symptoms, it's important to reach out to a doctor right away. They can recommend other options that won't interfere with your medication. Do not discontinue any medications without consulting a doctor.
NorethisteroneTelaprevir
Severe
How does the drug interact with Mendate 5 Tablet:
Using Telaprevir and Mendate 5 Tablet together can increase risk of unintended pregnancy and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Telaprevir with Mendate 5 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneGriseofulvin
Severe
How does the drug interact with Mendate 5 Tablet:
Taking griseofulvin with Mendate 5 Tablet may reduce blood levels and the effects of Mendate 5 Tablet.

How to manage the interaction:
Although there is a possible interaction between Griseofulvin and Mendate 5 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Mendate 5 Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Mendate 5 Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Mendate 5 Tablet dose.

Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

PROGESTIN

Mendate 5 Tablet 10's Substitute

Substitutes safety advice

  • Primolut-N Tablet 10's

    by Others

    ₹5.40per tablet

  • Regestrone 5 mg Tablet 10's

    by Others

    ₹5.40per tablet

  • Sysron-N Tablet 10's

    by Others

    ₹5.09per tablet

  • Prevent-N Tablet 10's

    by Others

    ₹5.40per tablet

  • DUB 5 mg Tablet 10's

    by AYUR

    ₹5.40per tablet

Product Substitutes

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Alcohol

Caution

The interaction of Mendate 5 Tablet 10's with alcohol is unknown. Please consult a doctor before consuming alcohol while using Mendate 5 Tablet 10's.

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Pregnancy

Unsafe

Mendate 5 Tablet 10's is a category X pregnancy drug and is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Mendate 5 Tablet 10's is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Mendate 5 Tablet 10's usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

Mendate 5 Tablet 10's is not recommended if you have liver disease. However, if you have any concerns regarding this, please consult a doctor.

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Kidney

Caution

Take Mendate 5 Tablet 10's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Mendate 5 Tablet 10's is not recommended for use in children under 18 years.

FAQs

Mendate 5 Tablet 10's is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Mendate 5 Tablet 10's may be used in the treatment of breast cancer.

Mendate 5 Tablet 10's contains Norethisterone, a synthetic hormone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Mendate 5 Tablet 10's may be used to delay periods. Mendate 5 Tablet 10's keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Mendate 5 Tablet 10's.

Mendate 5 Tablet 10's may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoking, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Mendate 5 Tablet 10's.

You are not recommended to take Mendate 5 Tablet 10's with rifampicin as it may decrease the levels of Mendate 5 Tablet 10's in blood and reduce its effectiveness. However, please consult a doctor before taking Mendate 5 Tablet 10's with other medicines.

Periods usually resume within 3 days of discontinuing Mendate 5 Tablet 10's. However, please consult a doctor if you have any concerns regarding this.

Mendate 5 Tablet 10's may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Mendate 5 Tablet 10's and inform your doctor if you have diabetes before taking Mendate 5 Tablet 10's.

No, Mendate 5 Tablet 10's is not a contraceptive on its own.

No, Mendate 5 Tablet 10's is unlikely to cause weight loss.

The recommended dosage can vary greatly depending on the reason for taking the medication. It's crucial to follow your doctor's instructions precisely. Taking an incorrect dosage can lead to ineffective treatment or adverse side effects.

No, Mendate 5 Tablet 10's does not cause miscarriages. However, it is not safe to take Mendate 5 Tablet 10's during pregnancy.

Mendate 5 Tablet 10's can generally be taken either before or after a meal. There is no strict requirement regarding the timing of food intake.

Mendate 5 Tablet 10's contains Norethisterone, a second-generation progestin.

The duration of Mendate 5 Tablet 10's use can vary depending on the specific medical condition being treated.

Yes, Mendate 5 Tablet 10's treats irregular menstrual cycles.

Even after taking Mendate 5 Tablet 10's and having unprotected sex, one can get pregnant. However, Mendate 5 Tablet 10's is a category X pregnancy drug. It is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

Common side effects of Mendate 5 Tablet 10's may cause unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhoea, headache, breast pain, and tenderness. Most of these side effects of Mendate 5 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Yes, Mendate 5 Tablet 10's can lead to weight gain in some persons. However, it's crucial to remember that this isn't a common adverse effect. The potential risk of weight gain varies based on the individual and the dosage. Talk to your doctor or pharmacist if you are concerned about weight gain or have any other questions regarding norethisterone acetate. They can provide personalized information based on your circumstances.

Limited research is available. Seek medical attention from your doctor if you have any questions. Remember that self-medication can be risky. Always consult with a healthcare professional for proper diagnosis and treatment.

Yes, bleeding may occasionally occur while taking Mendate 5 Tablet 10's. If you're experiencing bleeding while on Mendate 5 Tablet 10's and you're concerned, it's important to consult with your healthcare provider. They can determine if the bleeding is normal or if there's another underlying issue.

Mendate 5 Tablet 10's usually stops irregular bleeding within a few days, but this varies from person to person. If bleeding persists or worsens, consult your doctor.

The duration of Mendate 5 Tablet 10's use depends on your specific medical condition and the reason for taking it.

The exact dosage and schedule for Mendate 5 Tablet 10's will vary based on your individual health needs. It is important to follow your doctor's instructions to ensure effective treatment and minimize side effects.

If you forget a dose of Mendate 5 Tablet 10's, take it as soon as possible. If it's been more than 12 hours, skip the missed dose and continue with your regular schedule or as directed by the physician.

Yes, Mendate 5 Tablet 10's can interact with other medications. It's important to avoid taking Mendate 5 Tablet 10's with any medications without consulting your doctor first. They can assess the potential risks and benefits and recommend alternative treatments if necessary.

Store in a cool and dry place away from sunlight. Keep Mendate 5 Tablet 10's out of reach and out of sight to children.

Mendate 5 Tablet 10's can be used to treat long-term disorders like endometriosis. But you should talk to your doctor about the long-term advantages and risks.

Country of origin

India

Manufacturer/Marketer address

A-10, 3rd Floor, Art Guild House, Phoenix Market City Annexe, Lbs Marg, Kurla (West), Mumbai - 400070
Other Info - MEN0331

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Author Details

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Written By

Veda Maddala

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Apr 14, 2025 | 3:19 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.1494.pdf
  2. https://www.drugs.com/mtm/norethindrone.html
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