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Megmabend Leo 400mg/150mg Tablet
Megmabend Leo 400mg/150mg Tablet is used to treat parasitic worm infections. It contains albendazole and levamisole. Albendazole inhibits tubulin polymerization, causing metabolic disruption and energy depletion in the parasite, leading to immobilization. Levamisole suppresses the worm's muscle's enzyme activity, leading to paralysis and death; this eventually leads to the death of susceptible helminths and thus prevents the growth of parasitic infections.
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Megmabend Leo 400mg/150mg Tablet belongs to the class of medications called 'anthelmintics' used to treat parasitic worm infections. Parasitic worm infections are intestinal worm infections that are caused by the ingestion of contaminated food and water.
Megmabend Leo 400mg/150mg Tablet contains albendazole and levamisole. Albendazole works by inhibiting tubulin polymerization, causing metabolic disruption and energy depletion in the parasite, leading to immobilization. Levamisole works by suppressing the worm's muscle's enzyme activity, leading to paralysis and death. This eventually leads to the death of susceptible helminths and thus prevents the growth of parasitic infections.
Take Megmabend Leo 400mg/150mg Tablet as prescribed by your doctor. The common side-effects of Megmabend Leo 400mg/150mg Tablet are nausea, vomiting, indigestion, diarrhoea, metallic taste, headache, dizziness, and stomach pain. Most of these side effects do not require medical attention and resolve gradually over time. If any of the side effects persist or worsen, please consult your doctor.
Avoid taking Megmabend Leo 400mg/150mg Tablet if you are allergic to 'albendazole', 'levamisole', or any ingredients present in it. It may cause dizziness, so refrain from activities that require you to stay alert. Megmabend Leo 400mg/150mg Tablet is not recommended in pregnancy. Before taking Megmabend Leo 400mg/150mg Tablet, inform your doctor about your complete medical history.
Megmabend Leo 400mg/150mg Tablet contains 'Albendazole' and 'Levamisole', which belong to the class of medications called 'anthelmintics'. It is a broad-spectrum antibiotic used in the treatment of parasitic infections. It can kill the disease-causing worms and stop the spread of infection effectively. Albendazole interrupts the absorption of glucose by the worm, leading to energy depletion. Levamisole works by suppressing the enzyme activity in the worm's muscle; this leads to paralysis and death.
Do not take Megmabend Leo 400mg/150mg Tablet if you are allergic to any component present in it; if you are unsure, check with your healthcare professional. Due to the risk of liver or bone marrow damage during albendazole therapy, blood counts and liver function tests should be performed regularly (at least once every two weeks). Albendazole may cause fetal damage; thus, women of reproductive age should begin medication after a negative pregnancy test. Women of reproductive age should avoid becoming pregnant while taking Megmabend Leo 400mg/150mg Tablet or within one month of completing therapy. Megmabend Leo 400mg/150mg Tablet should be taken with food.
Drug-Drug Interactions: Megmabend Leo 400mg/150mg Tablet may interact with chemotherapy drugs (e.g. cladribine), antipsychotic medication (e.g. clozapine), live vaccinations (e.g. BCG vaccine, dengue vaccine, zoster vaccine)
Drug-Food Interactions: Alcohol consumption should be avoided.
Drug-Disease Interactions: Megmabend Leo 400mg/150mg Tablet should be used with caution in patients with myelosuppression (bone marrow suppression), hepatobiliary dysfunction (liver and biliary disease), neurological disorder (Intracranial Hypertension, Seizures), and renal dysfunction.
Parasitic worm infections: Parasitic worms are also called intestinal worms or helminths. They live in and feed on the hosts, leading to weakness and diseases. Common types of intestinal worms are roundworms and flatworms, such as tapeworms and flukes. Worm infections could occur due to consuming contaminated water, food, or soil, contact with contaminated faeces, poor sanitization, or poor hygiene. Symptoms of worm infections include abdominal pain, diarrhoea, nausea, vomiting, gas, bloating, fatigue, unexplained weight loss, and dysentery (bloody stools).
Alcohol
Caution
Megmabend Leo 400mg/150mg Tablet may interact with alcohol and worsen your condition. So, consumption of alcohol should be avoided.
Pregnancy
Caution
Megmabend Leo 400mg/150mg Tablet should not be used in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Megmabend Leo 400mg/150mg Tablet.
Breast Feeding
Safe if prescribed
Megmabend Leo 400mg/150mg Tablet is considered safe to be used in breastfeeding. However, consult your doctor before taking Megmabend Leo 400mg/150mg Tablet.
Driving
Caution
Megmabend Leo 400mg/150mg Tablet may cause dizziness, so do not drive or operate heavy machinery until you are alert.
Liver
Caution
In patients with hepatic dysfunction, Albendazole has been demonstrated to induce aplastic anaemia, agranulocytosis, and bone marrow suppression. Hence, Megmabend Leo 400mg/150mg Tablet should be used with caution in patients with liver disease. Dose adjustments may be necessary. So, discuss with your doctor before receiving Megmabend Leo 400mg/150mg Tablet if you have a history of liver diseases/conditions.
Kidney
Consult your doctor
Limited data is available. If you have kidney problems, inform your doctor before taking Megmabend Leo 400mg/150mg Tablet.
Children
Safe if prescribed
Megmabend Leo 400mg/150mg Tablet should be used in children only if clinically needed. Please consult your child's doctor for more information.
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