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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Meftal MR Tablet is used to provide relief from abdominal cramps due to the menstrual cycle. It contains Mefenamic acid and Tizanidine which work by blocking the chemical messengers that cause pain, relax the abdominal muscles and prevent muscle contractions. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, indigestion, and weakness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Blue Cross Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Meftal MR Tablet

Meftal MR Tablet belongs to a group of NSAID (Non-Steroidal Anti-Inflammatory Drug) medicines used to provide relief from abdominal cramps caused before and during the menstrual cycle. Abdominal cramps are throbbing pains in the lower abdomen due to the menstrual cycle every month in females. In some females, the pain and discomfort caused due to menstruation are so severe that they have to take some medicine to lower the pain intensity.

Meftal MR Tablet is a combination drug that contains 'mefenamic acid' and 'Tizanidine.' Mefenamic acid works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes, that make another chemical, 'prostaglandins' (PG) which are responsible for causing pain. Tizanidine works on the centres of the spinal cord and brain. This helps relax the intestine or stomach muscles and stops muscle contractions. Collectively, both of them help to relieve pain, bloating, cramps, and discomfort caused.

Take Meftal MR Tablet as prescribed. Depending on your medical condition, you are advised to take Meftal MR Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience common side effects, such as abdominal pain, nausea, vomiting, diarrhoea, indigestion, weakness, dry mouth, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please inform your doctor if you are allergic to Meftal MR Tablet or other medicines. Meftal MR Tablet can increase the risk of fatal heart attack or stroke, gastrointestinal bleeding, ulceration, and perforation of the stomach and intestines. Do not take Meftal MR Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Meftal MR Tablet may cause drowsiness and dizziness, so drive with caution. Meftal MR Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol and Meftal MR Tablet as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Do not take other painkillers with Meftal MR Tablet unless prescribed by the doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Meftal MR Tablet

Treatment of Abdominal cramps caused due to menstrual cycle.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Meftal MR Tablet is a combination drug that contains 'mefenamic acid' and 'Tizanidine.' Mefenamic acid belongs to a group of medicines called NSAID (Non-Steroidal Anti-Inflammatory Drug), used to relieve mild to moderate pain associated with period pain, symptoms of premenstrual syndrome (PMS), and management of excessively heavy periods. Meftal MR Tablet works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical, 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Tizanidine works in the centres of the spinal cord and brain. This helps relax the intestine or stomach muscles and stops muscle contractions. Collectively, both of them help to relieve pain, bloating, cramps, and discomfort caused.

How Meftal MR Tablet Works

Meftal MR Tablet is a combination drug that contains 'mefenamic acid' and 'Tizanidine.' Mefenamic acid works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes, that make another chemical, 'prostaglandins' (PG) which are responsible for causing pain. Tizanidine works on the centres of the spinal cord and brain. This helps relax the intestine or stomach muscles and stops muscle contractions. Collectively, both of them help to relieve pain, bloating, cramps, and discomfort caused.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Meftal MR Tablet

  • Abdominal pain 
  • Nausea 
  • Vomiting 
  • Diarrhoea 
  • Indigestion
  • Heartburn
  • Weakness
  • Dryness in the mouth

What if I have taken an overdose of Meftal MR Tablet

Take Meftal MR Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Please inform your doctor if you are allergic to Meftal MR Tablet or other medicines. Meftal MR Tablet can increase the risk of fatal heart attack or stroke, gastrointestinal bleeding, ulceration, and perforation of the stomach and intestines. Do not take Meftal MR Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Meftal MR Tablet may cause drowsiness and dizziness, so drive with caution. Meftal MR Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol and Meftal MR Tablet as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Do not take other painkillers with Meftal MR Tablet unless prescribed by the doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects. Avoid taking Meftal MR Tablet with fluvoxamine and ciprofloxacin as it may cause adverse effects such as slurred speech, dizziness, weakness, confusion, low blood pressure, or drowsiness. You are advised not to take more than three doses of Meftal MR Tablet in a single day as too much of Meftal MR Tablet may cause liver damage. If you have low blood pressure or liver or kidney diseases, inform your doctor before taking Meftal MR Tablet .

Drug-Drug Interactions

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TizanidineZiprasidone
Critical
TizanidineFluvoxamine
Critical

Drug-Drug Interactions

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TizanidineZiprasidone
Critical
How does the drug interact with Meftal MR Tablet 10's:
Co-administration of Meftal MR Tablet 10's with Ziprasidone can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Meftal MR Tablet 10's with Ziprasidone is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
TizanidineFluvoxamine
Critical
How does the drug interact with Meftal MR Tablet 10's:
Taking Fluvoxamine with Meftal MR Tablet 10's it can increases the risk of side effects.

How to manage the interaction:
Although Fluvoxamine with Meftal MR Tablet 10's is not recommended, but can be taken together if prescribed by a doctor. However, if you experience drowsiness, dizziness, low blood pressure, slurred speech, confusion, or severe weakness, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
TizanidineCiprofloxacin
Critical
How does the drug interact with Meftal MR Tablet 10's:
Coadministration of Ciprofloxacin and Meftal MR Tablet 10's together can increase the risk of side effects.

How to manage the interaction:
Using Ciprofloxacin and Meftal MR Tablet 10's together is avoided, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, weakness, sweating, or palpitations contact the doctor immediately. Do not discontinue any medications without consulting the doctor.
TizanidineSaquinavir
Critical
How does the drug interact with Meftal MR Tablet 10's:
Combining Meftal MR Tablet 10's with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Meftal MR Tablet 10's with Saquinavir is not recommended, as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TizanidineDronedarone
Critical
How does the drug interact with Meftal MR Tablet 10's:
Coadministration of Meftal MR Tablet 10's with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Meftal MR Tablet 10's with Dronedarone is generally avoided as it can result in an interaction, it can be taken when prescribed by a doctor. If you experience sudden dizziness, shortness of breath, palpitations, or chest pain, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TizanidineCisapride
Critical
How does the drug interact with Meftal MR Tablet 10's:
Coadministration of Meftal MR Tablet 10's with Cisapride can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Meftal MR Tablet 10's with Cisapride is avoided as it can result in an interaction, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience sudden dizziness, shortness of breath, palpitations, or vomiting. Do not discontinue any medications without consulting your doctor.
Mefenamic acidMeloxicam
Critical
How does the drug interact with Meftal MR Tablet 10's:
Co-administration of Meftal MR Tablet 10's with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Meftal MR Tablet 10's with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Meftal MR Tablet 10's:
Coadministration of Meftal MR Tablet 10's with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Meftal MR Tablet 10's with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
TizanidineHydrochlorothiazide
Severe
How does the drug interact with Meftal MR Tablet 10's:
The combined use of Meftal MR Tablet 10's and Hydrochlorothiazide can have additive effects in lowering your blood pressure.

How to manage the interaction:
Taking Meftal MR Tablet 10's and Hydrochlorothiazide together can possibly result in an interaction, but they can be taken if advised by your doctor. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
TizanidineIvabradine
Severe
How does the drug interact with Meftal MR Tablet 10's:
Coadministration of Ivabradine with Meftal MR Tablet 10's can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Ivabradine with Meftal MR Tablet 10's together can result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Massages can also be helpful.
  • Avoid having too spicy and junk food and instead eat home-cooked food as it will help to lower contracting and make the job of the stomach easier.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • Stay hydrated, and drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Meftal MR Tablet Substitute

Substitutes safety advice
  • Mefcan TN 500mg/2mg Tablet

    6.30per tablet
  • Mefedrot MR 500mg/2mg Tablet

    3.96per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Meftal MR Tablet as it may increase the risk of adverse effects.

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Pregnancy

Caution

Meftal MR Tablet belongs to pregnancy category C. Please consult your doctor before taking the Meftal MR Tablet if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Meftal MR Tablet is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding. Meftal MR Tablet is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Meftal MR Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Meftal MR Tablet should not be given to children as safety and effectiveness were not established.

FAQs

Meftal MR Tablet is used to provide relief from abdominal cramps caused by the menstrual cycle.
Meftal MR Tablet is a combination drug that contains 'mefenamic acid' and 'Tizanidine.' Mefenamic acid works by blocking the effect of a chemical messenger in your body, which is responsible for causing pain. Tizanidine works in the centres of the spinal cord and brain. This helps relax the intestine or stomach muscles and stops muscle contractions. Collectively, both of them help to relieve pain, bloating, cramps, and discomfort caused.
Meftal MR Tablet is used to relieve menstrual (period) pain, premenstrual syndrome (PMS) symptoms, and management of excessively heavy periods. Take only as prescribed by the doctor.
You are not recommended to take Meftal MR Tablet with ciprofloxacin as Meftal MR Tablet contains Tizanidine. Co-administrating these two medicines may cause adverse effects such as slurred speech, dizziness, weakness, confusion, low blood pressure, and drowsiness. However, please consult a doctor before taking Meftal MR Tablet with other medicines.
Avoid taking Meftal MR Tablet if you have stomach ulcers as Meftal MR Tablet contains Mefenamine, which might increase the risk of stomach ulcers, perforation of the stomach and intestinal bleeding with higher doses.
Do not take Meftal MR Tablet if you are planning for pregnancy as Meftal MR Tablet might make it more difficult to get pregnant.
Diarrhoea might be a side-effect of Meftal MR Tablet . Drink plenty of fluids and eat food rich in fibre. Consult your doctor if you experience excessive diarrhoea or if you find blood in stools.

Country of origin

India

Manufacturer/Marketer address

Peninsula Chambers, Peninsula Corporate Park, G.K Marg, Lower Parel (West), Mumbai - 400013, Maharashtra, INDIA.
Other Info - MEF0017

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